Jan Astermark

Professor, consultant
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  1. 2021
  2. Real-world prophylactic usage of recombinant factor VIII Fc in Sweden: A report from the Swedish national registry for bleeding disorders

    Margareta Holmström, Elsa Olsson, Jan Astermark, Malin Axelsson, Anna Olsson, Linda Myrin Westesson, Aletta Falk, Johan Szamosi & Karin Sennfält, 2021 May 13, In: Haemophilia.

    Research output: Contribution to journalLetter

  3. Comparison of single subject and population-based pharmacokinetics for optimizing prophylaxis with simoctocog alfa in patients with haemophilia A

    Jan Astermark, Anna Olsson, Pierre Chelle, Kinga Täckström, Maria Walger, Maria Magnusson & Alfonso Iorio, 2021 May 9, In: Haemophilia.

    Research output: Contribution to journalArticle

  4. Droplet digital PCR and mile-post analysis for the detection of F8 int1h inversions

    Eric Manderstedt, Christina Lind-Halldén, Rolf Ljung, Jan Astermark & Christer Halldén, 2021, In: Journal of Thrombosis and Haemostasis. 19, 3, p. 732-737

    Research output: Contribution to journalArticle

  5. Haemophilia early arthropathy detection with ultrasound and haemophilia joint health score in the moderate haemophilia (MoHem) study

    Ragnhild J. Måseide, Erik Berntorp, Jan Astermark, Jessica Hansen, Anna Olsson, Maria Bruzelius, Tony Frisk, Magnus Aspdahl, Vuokko Nummi, Geir E. Tjønnfjord & P. Holme, 2021, In: Haemophilia. 27, 2

    Research output: Contribution to journalArticle

  6. Recombinant FVIIa in elective non-orthopaedic surgery of adults with haemophilia and inhibitors: A systematic literature review

    Gerard Dolan, Jan Astermark & Cedric Hermans, 2021, In: Haemophilia.

    Research output: Contribution to journalReview article

  7. The B-Natural study—The outcome of immune tolerance induction therapy in patients with severe haemophilia B

    Jan Astermark, Katharina Holstein, Yasmina L. Abajas, Susan Kearney, Stacy E. Croteau, Riana Liesner, Eva Funding, Christine L. Kempton, Suchitra Acharya, Stefan Lethagen, Petra LeBeau, Joel Bowen, Erik Berntorp & Amy D. Shapiro, 2021, In: Haemophilia.

    Research output: Contribution to journalArticle

  8. Treatment outcomes in persons with severe haemophilia B in the Nordic region: The B-NORD study

    Kristina Kihlberg, Fariba Baghaei, Maria Bruzelius, Eva Funding, Pål Andre Holme, Riitta Lassila, Vuokko Nummi, Susanna Ranta, Mehdi Osooli, Erik Berntorp & Jan Astermark, 2021, In: Haemophilia.

    Research output: Contribution to journalArticle

  9. Validation of factor VIII activity for monitoring standard and extended half-life products and correlation to thrombin generation assays

    Cecilia Augustsson, Eva Norström, Vivian Lind, Myriam Martin, Jan Astermark & Karin Strandberg, 2021, In: Haemophilia.

    Research output: Contribution to journalArticle

  10. 2020
  11. Detection of mosaics in hemophilia A by deep Ion Torrent sequencing and droplet digital PCR

    Eric Manderstedt, Rosanna Nilsson, Rolf Ljung, Christina Lind-Halldén, Jan Astermark & Christer Halldén, 2020 Oct, In: Research and practice in thrombosis and haemostasis. 4, 7, p. 1121-1130 10 p.

    Research output: Contribution to journalArticle

  12. Joint health and treatment modalities in Nordic patients with moderate haemophilia A and B – The MoHem study

    Ragnhild J. Måseide, Erik Berntorp, Jan Astermark, Anna Olsson, Maria Bruzelius, Tony Frisk, Vuokko Nummi, Riitta Lassila, Geir E. Tjønnfjord & Pål A. Holme, 2020 Sep, In: Haemophilia. 26, 5, p. 891-897 7 p.

    Research output: Contribution to journalArticle

  13. Detection of F8 int22h inversions using digital droplet PCR and mile-post assays

    Eric Manderstedt, Christina Lind-Halldén, Rolf Ljung, Jan Astermark & Christer Halldén, 2020 May, In: Journal of Thrombosis and Haemostasis. 18, 5, p. 1039-1049 11 p.

    Research output: Contribution to journalArticle

  14. 2019
  15. Targeted re-sequencing of F8, F9 and VWF: Characterization of Ion Torrent data and clinical implications for mutation screening

    Eric Manderstedt, Rosanna Nilsson, Christina Lind-Halldén, Rolf Ljung, Jan Astermark & Christer Halldén, 2019 Apr 26, In: PLoS ONE. 14, 4, e0216179.

    Research output: Contribution to journalArticle

  16. Hypertension and cardiovascular diseases in Swedish persons with haemophilia — A longitudinal registry study

    Susanna Lövdahl, Karin M. Henriksson, Fariba Baghaei, Margareta Holmström, Erik Berntorp & Jan Astermark, 2019, In: Thrombosis Research. 181, Sept., p. 106-111

    Research output: Contribution to journalArticle

  17. Joint comorbidities among Swedish carriers of haemophilia: A register-based cohort study over 22 years

    Mehdi Osooli, Sharyne M. Donfield, Katarina Steen Carlsson, Fariba Baghaei, Margareta Holmström, Erik Berntorp & Jan Astermark, 2019, In: Haemophilia. 25, 5, p. 845-850

    Research output: Contribution to journalArticle

  18. Sports participation and physical activity in adult Dutch and Swedish patients with severe haemophilia: A comparison between intermediate- and high-dose prophylaxis

    Olav Versloot, Erik Berntorp, Pia Petrini, Rolf Ljung, Jan Astermark, Margareta Holmström, Piet de Kleijn & Kathelijn Fischer, 2019, In: Haemophilia. 25, 2, p. 244-251

    Research output: Contribution to journalArticle

  19. 2018
  20. The role of the laboratory in diagnosis and management of inhibitory antibodies in haemophilia

    K. Strandberg & J. Astermark, 2018 May 1, In: Haemophilia. 24, p. 9-14 6 p.

    Research output: Contribution to journalArticle

  21. 2017
  22. Intensity of factor VIII treatment and the development of inhibitors in non-severe hemophilia A patients: Results of the INSIGHT case-control study

    Alice S. van Velzen, C. L. Eckhardt, M. Peters, F. W. G. Leebeek, C. Escuriola-Ettingshausen, C Hermans, Russell D. Keenan, J. Astermark, Christoph Male, K Peerlinck, Saskia le Cessie, J. G. Van der Bom & K. Fijnvandraat, 2017 Jul 3, In: Journal of Thrombosis and Haemostasis. 15, 7, p. 1422-1429

    Research output: Contribution to journalArticle

  23. Comparative burden of arthropathy in mild haemophilia: a register-based study in Sweden

    M Osooli, S Lövdahl, K Steen Carlsson, K Knobe, F. Baghaei, M Holmström, J Astermark & E Berntorp, 2017 Mar, In: Haemophilia. 23, 2, p. e79-e86

    Research output: Contribution to journalArticle

  24. Anti-factor VIII antibodies in brothers with haemophilia A share similar characteristics

    J. Kahle, A. Orlowski, D. Stichel, J. F. Healey, E. T. Parker, S. M. Donfield, J. Astermark, E. Berntorp, P. Lollar, D. Schwabe & C. Königs, 2017, In: Haemophilia. 23, 2, p. 292-299

    Research output: Contribution to journalArticle

  25. Discrepancies between the one-stage clotting assay and the chromogenic assay in haemophilia B

    K. Kihlberg, K. Strandberg, S. Rosén, R. Ljung & J. Astermark, 2017, In: Haemophilia. 23, 4, p. 620-627

    Research output: Contribution to journalArticle

  26. The association between health utility and joint status among people with severe haemophilia A: findings from the KAPPA register

    M Osooli, K Steen Carlsson, F Baghaei, M Holmström, S. Rauchensteiner, P A Holme, L Hvitfeldt, J Astermark & E Berntorp, 2017, In: Haemophilia. 23, 3, p. e180-e187

    Research output: Contribution to journalArticle

  27. The importance of genetic factors for the development of arthropathy: A longitudinal study of children and adolescents with haemophilia A

    Edward D Gomperts, John Schwarz, Sharyne M. Donfield, Alice E. Lail, Jan Astermark, W. Keith Hoots, Cheryl A. Winkler & Erik Berntorp, 2017, In: Thrombosis and Haemostasis. 117, 2, p. 277-285 9 p.

    Research output: Contribution to journalArticle

  28. 2016
  29. Current view and outcome of ITI therapy: A change over time?

    K. Holstein, A. Batorova, M. Carvalho, K. Fijnvandraat, P. Holme, K. Kavakli, T. Lambert, A. Rocino, V. Jiménez-Yuste & J. Astermark, 2016 Dec, In: Thrombosis Research. 148, p. 38-44

    Research output: Contribution to journalArticle

  30. Malignancies in Swedish persons with haemophilia: a longitudinal registry study

    Susanna Lövdahl, K M Henriksson, Fariba Baghaei, Margareta Holmström, Erik Berntorp & Jan Astermark, 2016 Sep, In: Blood Coagulation and Fibrinolysis. 27, 6, p. 631–636

    Research output: Contribution to journalArticle

  31. Partnering to change the world for people with haemophilia: 6th Haemophilia Global Summit, Prague, Czech Republic, 24–26th September 2015

    Jan Astermark, Dan Hart, Sébastien Lobet, Jan Blatný, Roseline d'Oiron, Gili Kenet, Gerry Dolan, Valérie Libotte & Cedric Hermans, 2016 Jul 1, In: European Journal of Haematology. 97, p. 3-23 21 p.

    Research output: Contribution to journalPublished meeting abstract

  32. 2015
  33. FVIII inhibitors: pathogenesis and avoidance.

    Jan Astermark, 2015, In: Blood. 125, 13, p. 2045-2051

    Research output: Contribution to journalReview article

  34. Genetic risk factors for inhibitors in haemophilia A

    Edit Bardi & Jan Astermark, 2015, In: European Journal of Haematology. 94, p. 7-10

    Research output: Contribution to journalReview article

  35. Non-genetic risk factors and their influence on the management of patients in the clinic

    Teresa Alvarez, Immaculada Soto & Jan Astermark, 2015, In: European Journal of Haematology. 94, p. 2-6

    Research output: Contribution to journalReview article

  36. Strategies for reducing inhibitor formation in severe haemophilia

    Oliver Tunstall & Jan Astermark, 2015, In: European Journal of Haematology. 94, p. 45-50

    Research output: Contribution to journalReview article

  37. 2014
  38. A longitudinal study of family structure in Swedish persons with haemophilia.

    Susanna Lövdahl, K M Henriksson, F Baghaei, M Holmström, Erik Berntorp & Jan Astermark, 2014, In: Haemophilia. 20, 4, p. 493-499

    Research output: Contribution to journalArticle

  39. Immunosuppressive agents in the treatment of inhibitors in congenital haemophilia A and B - a systematic literature review

    Britta Antonia Petra Laros-van Gorkom, Celine Falaise & Jan Astermark, 2014, In: European Journal of Haematology. 93, p. 26-38

    Research output: Contribution to journalReview article

  40. Managing Haemophilia for Life: 4th Haemophilia Global Summit

    Jan Astermark, G. Dolan, T. Hilberg, V. Jimenez-Yuste, M. Laffan, R. Lassila, S. Lobet, C. Martinoli & C. -F. Perno, 2014, In: Haemophilia. 20, p. 1-20

    Research output: Contribution to journalReview article

  41. Switching clotting factor concentrates: considerations in estimating the risk of immunogenicity

    D. Matino, D. Lillicrap, Jan Astermark, G. Dolan, C. Kessler, T. Lambert, M. Makris, J. O'Donnell, S. Pipe, E. Santagostino, J. -M. Saint-Remy, W. Schramm & A. Iorio, 2014, In: Haemophilia. 20, 2, p. 200-206

    Research output: Contribution to journalArticle

  42. The Fc gamma receptor IIa R131H polymorphism is associated with inhibitor development in severe hemophilia A

    C. L. Eckhardt, Jan Astermark, S. Q. Nagelkerke, J. Geissler, M. W. T. Tanck, M. Peters, K. Fijnvandraat & T. W. Kuijpers, 2014, In: Journal of Thrombosis and Haemostasis. 12, 8, p. 1294-1301

    Research output: Contribution to journalArticle

  43. 2013
  44. F8 haplotype and inhibitor risk: results from the Hemophilia Inhibitor Genetics Study (HIGS) Combined Cohort

    J. Schwarz, Jan Astermark, E. D. Menius, M. Carrington, S. M. Donfield, E. D. Gomperts, G. W. Nelson, J. Oldenburg, A. Pavlova, A. D. Shapiro, C. A. Winkler & Erik Berntorp, 2013, In: Haemophilia. 19, 1, p. 113-118

    Research output: Contribution to journalArticle

  45. Factor VIII gene (F8) mutation and risk of inhibitor development in nonsevere hemophilia A

    Corien L. Eckhardt, Alice S. van Velzen, Marjolein Peters, Jan Astermark, Paul P. Brons, Giancarlo Castaman, Marjon H. Cnossen, Natasja Dors, Carmen Escuriola-Ettingshausen, Karly Hamulyak, Daniel P. Hart, Charles R. M. Hay, Saturnino Haya, Waander L. van Heerde, Cedric Hermans, Margareta Holmstrom, Victor Jimenez-Yuste, Russell D. Keenan, Robert Klamroth, Britta A. P. Laros-van Gorkom & 25 others, Frank W. G. Leebeek, Ri Liesner, Anne Makipernaa, Christoph Male, Evelien Mauser-Bunschoten, Maria G. Mazzucconi, Simon Mcrae, Karina Meijer, Michael Mitchell, Massimo Morfini, Marten Nijziel, Johannes Oldenburg, Kathelijne Peerlinck, Pia Petrini, Helena Platokouki, Sylvia E. Reitter-Pfoertner, Elena Santagostino, Piercarla Schinco, Frans J. Smiers, Berthold Siegmund, Annarita Tagliaferri, Thynn T. Yee, Pieter Willem Kamphuisen, Johanna G. van der Bom & Karin Fijnvandraat, 2013, In: Blood. 122, 11, p. 1954-1962

    Research output: Contribution to journalArticle

  46. Incidence, mortality rates and causes of deaths in haemophilia patients in Sweden.

    Susanna Lövdahl, Marie Henriksson, F Baghaei, Eva M Holmström, J-Å Nilsson, Erik Berntorp & Jan Astermark, 2013, In: Haemophilia. 19, 3, p. 362-369

    Research output: Contribution to journalArticle

  47. The polygenic nature of inhibitors in hemophilia A: results from the Hemophilia Inhibitor Genetics Study (HIGS) Combined Cohort.

    Jan Astermark, Sharyne M Donfield, Edward D Gomperts, John Schwarz, Erika D Menius, Anna Pavlova, Johannes Oldenburg, Bailey Kessing, Donna M Dimichele, Amy D Shapiro, Cheryl A Winkler & Erik Berntorp, 2013, In: Blood. 121, 8, p. 1446-1454

    Research output: Contribution to journalArticle

  48. 2012
  49. Daily dosing prophylaxis for haemophilia: a randomized crossover pilot study evaluating feasibility and efficacy.

    Karin Lindvall, Jan Astermark, S Björkman, R Ljung, K S Carlsson, S Persson & Erik Berntorp, 2012, In: Haemophilia. 18, 6, p. 855-859

    Research output: Contribution to journalArticle

  50. Exposure to factor VIII and prediction of inhibitor development: exposure days vs. danger days, or both?

    C. Hermans, Jan Astermark & P. De Moerloos, 2012, In: Journal of Thrombosis and Haemostasis. 10, 10, p. 2194-2196

    Research output: Contribution to journalLetter

  51. F8 gene mutation type and inhibitor development in patients with severe hemophilia A: systematic review and meta-analysis

    Samantha C. Gouw, H. Marijke van den Berg, Johannes Oldenburg, Jan Astermark, Philip G. de Groot, Maurizio Margaglione, Arthur R. Thompson, Waander van Heerde, Jorien Boekhorst, Connie H. Miller, Saskia le Cessie & Johanna G. van der Bom, 2012, In: Blood. 119, 12, p. 2922-2934

    Research output: Contribution to journalReview article

  52. Malignant disease in the haemophilic population: moving towards a management consensus?

    Jan Astermark, M Makris, E Mauser-Bunschoten, L Nemes, R D'oiron, J Oldenburg & J Ingerslev, 2012, In: Haemophilia. 18, 5, p. 664-671

    Research output: Contribution to journalArticle

  53. Prevention and prediction of inhibitor risk.

    Jan Astermark, 2012, In: Haemophilia. 18 Suppl 4, p. 38-42

    Research output: Contribution to journalArticle

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