Jan Astermark

Professor, consultant
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  1. 2019
  2. Targeted re-sequencing of F8, F9 and VWF: Characterization of Ion Torrent data and clinical implications for mutation screening

    Manderstedt, E., Nilsson, R., Lind-Halldén, C., Rolf Ljung, Jan Astermark & Halldén, C., 2019 Apr 26, In : PLoS ONE. 14, 4, e0216179.

    Research output: Contribution to journalArticle

  3. Sports participation and physical activity in adult Dutch and Swedish patients with severe haemophilia: A comparison between intermediate- and high-dose prophylaxis

    Versloot, O., Erik Berntorp, Petrini, P., Rolf Ljung, Jan Astermark, Holmström, M., de Kleijn, P. & Fischer, K., 2019, In : Haemophilia. 25, 2, p. 244-251

    Research output: Contribution to journalArticle

  4. 2018
  5. The role of the laboratory in diagnosis and management of inhibitory antibodies in haemophilia

    Strandberg, K. & J. Astermark, 2018 May 1, In : Haemophilia. 24, p. 9-14 6 p.

    Research output: Contribution to journalArticle

  6. 2017
  7. Intensity of factor VIII treatment and the development of inhibitors in non-severe hemophilia A patients: Results of the INSIGHT case-control study

    van Velzen, A. S., Eckhardt, C. L., Peters, M., Leebeek, F. W. G., Escuriola-Ettingshausen, C., Hermans, C., Keenan, R. D., J. Astermark, Male, C., Peerlinck, K., le Cessie, S., Van der Bom, J. G. & Fijnvandraat, K., 2017 Jul 3, In : Journal of Thrombosis and Haemostasis. 15, 7, p. 1422-1429

    Research output: Contribution to journalArticle

  8. Comparative burden of arthropathy in mild haemophilia: a register-based study in Sweden

    M Osooli, Lövdahl, S., K Steen Carlsson, Knobe, K., Baghaei, F., Holmström, M., J Astermark & E Berntorp, 2017 Mar, In : Haemophilia. 23, 2, p. e79-e86

    Research output: Contribution to journalArticle

  9. Anti-factor VIII antibodies in brothers with haemophilia A share similar characteristics

    Kahle, J., Orlowski, A., Stichel, D., Healey, J. F., Parker, E. T., Donfield, S. M., J. Astermark, E. Berntorp, Lollar, P., Schwabe, D. & Königs, C., 2017, In : Haemophilia. 23, 2, p. 292-299

    Research output: Contribution to journalArticle

  10. Discrepancies between the one-stage clotting assay and the chromogenic assay in haemophilia B

    K. Kihlberg, Strandberg, K., Rosén, S., R. Ljung & J. Astermark, 2017, In : Haemophilia. 23, 4, p. 620-627

    Research output: Contribution to journalArticle

  11. The association between health utility and joint status among people with severe haemophilia A: findings from the KAPPA register

    M Osooli, K Steen Carlsson, Baghaei, F., Holmström, M., Rauchensteiner, S., Holme, P. A., Hvitfeldt, L., J Astermark & E Berntorp, 2017, In : Haemophilia. 23, 3, p. e180-e187

    Research output: Contribution to journalArticle

  12. The importance of genetic factors for the development of arthropathy: A longitudinal study of children and adolescents with haemophilia A

    Gomperts, E. D., Schwarz, J., Donfield, S. M., Lail, A. E., Jan Astermark, Keith Hoots, W., Winkler, C. A. & Erik Berntorp, 2017, In : Thrombosis and Haemostasis. 117, 2, p. 277-285 9 p.

    Research output: Contribution to journalArticle

  13. 2016
  14. Current view and outcome of ITI therapy: A change over time?

    Holstein, K., Batorova, A., Carvalho, M., Fijnvandraat, K., Holme, P., Kavakli, K., Lambert, T., Rocino, A., Jiménez-Yuste, V. & J. Astermark, 2016 Dec, In : Thrombosis Research. 148, p. 38-44

    Research output: Contribution to journalArticle

  15. Malignancies in Swedish persons with haemophilia: a longitudinal registry study

    Lövdahl, S., Henriksson, K. M., Baghaei, F., Holmström, M., Erik Berntorp & Jan Astermark, 2016 Sep, In : Blood Coagulation and Fibrinolysis. 27, 6, p. 631–636

    Research output: Contribution to journalArticle

  16. Partnering to change the world for people with haemophilia: 6th Haemophilia Global Summit, Prague, Czech Republic, 24–26th September 2015

    Jan Astermark, Hart, D., Lobet, S., Blatný, J., d'Oiron, R., Kenet, G., Dolan, G., Libotte, V. & Hermans, C., 2016 Jul 1, In : European Journal of Haematology. 97, p. 3-23 21 p.

    Research output: Contribution to journalPublished meeting abstract

  17. 2015
  18. FVIII inhibitors: pathogenesis and avoidance.

    Jan Astermark, 2015, In : Blood. 125, 13, p. 2045-2051

    Research output: Contribution to journalReview article

  19. Genetic risk factors for inhibitors in haemophilia A

    Bardi, E. & Jan Astermark, 2015, In : European Journal of Haematology. 94, p. 7-10

    Research output: Contribution to journalReview article

  20. Non-genetic risk factors and their influence on the management of patients in the clinic

    Alvarez, T., Soto, I. & Jan Astermark, 2015, In : European Journal of Haematology. 94, p. 2-6

    Research output: Contribution to journalReview article

  21. Strategies for reducing inhibitor formation in severe haemophilia

    Tunstall, O. & Jan Astermark, 2015, In : European Journal of Haematology. 94, p. 45-50

    Research output: Contribution to journalReview article

  22. 2014
  23. A longitudinal study of family structure in Swedish persons with haemophilia.

    Lövdahl, S., Henriksson, K. M., Baghaei, F., Holmström, M., Erik Berntorp & Jan Astermark, 2014, In : Haemophilia. 20, 4, p. 493-499

    Research output: Contribution to journalArticle

  24. Immunosuppressive agents in the treatment of inhibitors in congenital haemophilia A and B - a systematic literature review

    Laros-van Gorkom, B. A. P., Falaise, C. & Jan Astermark, 2014, In : European Journal of Haematology. 93, p. 26-38

    Research output: Contribution to journalReview article

  25. Managing Haemophilia for Life: 4th Haemophilia Global Summit

    Jan Astermark, Dolan, G., Hilberg, T., Jimenez-Yuste, V., Laffan, M., Lassila, R., Lobet, S., Martinoli, C. & Perno, C. -F., 2014, In : Haemophilia. 20, p. 1-20

    Research output: Contribution to journalReview article

  26. Switching clotting factor concentrates: considerations in estimating the risk of immunogenicity

    Matino, D., Lillicrap, D., Jan Astermark, Dolan, G., Kessler, C., Lambert, T., Makris, M., O'Donnell, J., Pipe, S., Santagostino, E., Saint-Remy, J. -M., Schramm, W. & Iorio, A., 2014, In : Haemophilia. 20, 2, p. 200-206

    Research output: Contribution to journalArticle

  27. The Fc gamma receptor IIa R131H polymorphism is associated with inhibitor development in severe hemophilia A

    Eckhardt, C. L., Jan Astermark, Nagelkerke, S. Q., Geissler, J., Tanck, M. W. T., Peters, M., Fijnvandraat, K. & Kuijpers, T. W., 2014, In : Journal of Thrombosis and Haemostasis. 12, 8, p. 1294-1301

    Research output: Contribution to journalArticle

  28. 2013
  29. F8 haplotype and inhibitor risk: results from the Hemophilia Inhibitor Genetics Study (HIGS) Combined Cohort

    Schwarz, J., Jan Astermark, Menius, E. D., Carrington, M., Donfield, S. M., Gomperts, E. D., Nelson, G. W., Oldenburg, J., Pavlova, A., Shapiro, A. D., Winkler, C. A. & Erik Berntorp, 2013, In : Haemophilia. 19, 1, p. 113-118

    Research output: Contribution to journalArticle

  30. Factor VIII gene (F8) mutation and risk of inhibitor development in nonsevere hemophilia A

    Eckhardt, C. L., van Velzen, A. S., Peters, M., Astermark, J., Brons, P. P., Castaman, G., Cnossen, M. H., Dors, N., Escuriola-Ettingshausen, C., Hamulyak, K., Hart, D. P., Hay, C. R. M., Haya, S., van Heerde, W. L., Hermans, C., Holmstrom, M., Jimenez-Yuste, V., Keenan, R. D., Klamroth, R., Laros-van Gorkom, B. A. P. & 25 othersLeebeek, F. W. G., Liesner, R., Makipernaa, A., Male, C., Mauser-Bunschoten, E., Mazzucconi, M. G., Mcrae, S., Meijer, K., Mitchell, M., Morfini, M., Nijziel, M., Oldenburg, J., Peerlinck, K., Petrini, P., Platokouki, H., Reitter-Pfoertner, S. E., Santagostino, E., Schinco, P., Smiers, F. J., Siegmund, B., Tagliaferri, A., Yee, T. T., Kamphuisen, P. W., van der Bom, J. G. & Fijnvandraat, K., 2013, In : Blood. 122, 11, p. 1954-1962

    Research output: Contribution to journalArticle

  31. Incidence, mortality rates and causes of deaths in haemophilia patients in Sweden.

    Lövdahl, S., Henriksson, M., Baghaei, F., Holmström, E. M., Nilsson, J-Å., Erik Berntorp & Jan Astermark, 2013, In : Haemophilia. 19, 3, p. 362-369

    Research output: Contribution to journalArticle

  32. The polygenic nature of inhibitors in hemophilia A: results from the Hemophilia Inhibitor Genetics Study (HIGS) Combined Cohort.

    Jan Astermark, Donfield, S. M., Gomperts, E. D., Schwarz, J., Menius, E. D., Pavlova, A., Oldenburg, J., Kessing, B., Dimichele, D. M., Shapiro, A. D., Winkler, C. A. & Erik Berntorp, 2013, In : Blood. 121, 8, p. 1446-1454

    Research output: Contribution to journalArticle

  33. 2012
  34. Daily dosing prophylaxis for haemophilia: a randomized crossover pilot study evaluating feasibility and efficacy.

    Lindvall, K., Jan Astermark, Björkman, S., Ljung, R., Carlsson, K. S., Persson, S. & Erik Berntorp, 2012, In : Haemophilia. 18, 6, p. 855-859

    Research output: Contribution to journalArticle

  35. Exposure to factor VIII and prediction of inhibitor development: exposure days vs. danger days, or both?

    Hermans, C., Jan Astermark & De Moerloos, P., 2012, In : Journal of Thrombosis and Haemostasis. 10, 10, p. 2194-2196

    Research output: Contribution to journalLetter

  36. F8 gene mutation type and inhibitor development in patients with severe hemophilia A: systematic review and meta-analysis

    Gouw, S. C., van den Berg, H. M., Oldenburg, J., Jan Astermark, de Groot, P. G., Margaglione, M., Thompson, A. R., van Heerde, W., Boekhorst, J., Miller, C. H., le Cessie, S. & van der Bom, J. G., 2012, In : Blood. 119, 12, p. 2922-2934

    Research output: Contribution to journalReview article

  37. Malignant disease in the haemophilic population: moving towards a management consensus?

    Jan Astermark, Makris, M., Mauser-Bunschoten, E., Nemes, L., D'oiron, R., Oldenburg, J. & Ingerslev, J., 2012, In : Haemophilia. 18, 5, p. 664-671

    Research output: Contribution to journalArticle

  38. Prevention and prediction of inhibitor risk.

    Jan Astermark, 2012, In : Haemophilia. 18 Suppl 4, p. 38-42

    Research output: Contribution to journalArticle

  39. The Arosenius Fund.

    Jan Astermark, 2012, In : Haemophilia. 18, p. 41462

    Research output: Contribution to journalArticle

  40. The international factor IX treatment network survey.

    Erik Berntorp, Shapiro, A. D., Waters, J. & Jan Astermark, 2012, In : Haemophilia. 18, 3, p. e60-e62

    Research output: Contribution to journalLetter

  41. Treatment of haemophilia A and B and von Willebrand's disease: summary and conclusions of a systematic review as part of a Swedish health-technology assessment.

    Erik Berntorp, Jan Astermark, Baghaei, F., Bergqvist, D., Holmström, M., Bengt Ljungberg, Norlund, A., Palmblad, J., Petrini, A., Stigendal, L. & Säwe, J., 2012, In : Haemophilia. 18, 2, p. 158-165

    Research output: Contribution to journalArticle

  42. 2011
  43. Bone density and health-related quality of life in adult patients with severe haemophilia.

    Khawaji, M., Jan Astermark, VON Mackensen, S., Kristina Åkesson & Erik Berntorp, 2011, In : Haemophilia. 17, 2, p. 304-311

    Research output: Contribution to journalArticle

  44. Clinical effect of increasing doses of lenalidomide in high-risk myelodysplastic syndrome and acute myeloid leukemia with chromosome 5 abnormalities

    Mollgard, L., Saft, L., Treppendahl, M. B., Dybedal, I., Norgaard, J. M., Jan Astermark, Ejerblad, E., Garelius, H., Dufva, I. H., Jansson, M., Jadersten, M., Kjeldsen, L., Linder, O., Nilsson, L., Vestergaard, H., Porwit, A., Gronbaek, K. & Lindberg, E. H., 2011, In : Haematologica. 96, 7, p. 963-971

    Research output: Contribution to journalArticle

  45. Immune tolerance induction in patients with hemophilia A

    Jan Astermark, 2011, In : Thrombosis Research. 127, p. S6-S9

    Research output: Contribution to journalArticle

  46. Quality of life, physical function and MRI T2*in elderly low-risk MDS patients treated to a haemoglobin level of >= 120 g/L with darbepoetin alfa +/- filgrastim or erythrocyte transfusions

    Nilsson-Ehle, H., Birgegård, G., Samuelsson Johannesson, J., Antunovic, P., Jan Astermark, Garelius, H., Engström, L., Kjeldsen, L., Nilsson, L., Olsson, A., Skov-Holm, M., Wallvik, J., Gulbrandsen, N. & Hellström-Lindberg, E., 2011, In : European Journal of Haematology. 87, 3, p. 244-252

    Research output: Contribution to journalArticle

  47. Recommendations for assessment, monitoring and follow-up of patients with haemophilia.

    DE Moerloose, P., Fischerström, K., Lambert, T., Windyga, J., Batorova, A., Lavigne-Lissalde, G., Rocino, A., Jan Astermark & Hermans, C., 2011, In : Haemophilia.

    Research output: Contribution to journalArticle

  48. The international factor IX treatment network survey

    Erik Berntorp, Waters, J., Jan Astermark, Donfield, S. M. & Shapiro, D., 2011, In : Haemophilia. 17, 2, p. 31

    Research output: Contribution to journalPublished meeting abstract

  49. 2010
  50. Assessment of health-related quality of life in patients with severe haemophilia with reduced bone density

    Khawaji, M., Jan Astermark & Erik Berntorp, 2010, In : Haemophilia. 16, p. 135-136

    Research output: Contribution to journalPublished meeting abstract

  51. Clinical issues in inhibitors

    Jan Astermark, Santagostino, E. & Hoots, W. K., 2010, In : Haemophilia. 16, p. 54-60

    Research output: Contribution to journalReview article

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