Kazi Uddin

Associate Researcher, Docent, PhDKnown as name: Julhash U. Kazi
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  1. Article
  2. FMS-like Tyrosine Kinase 3/FLT3: From Basic Science to Clinical Implications

    Julhash U. Kazi & Lars Rönnstrand, 2019, In : Physiological Reviews. 99, 3, p. 1433-1466 34 p.

    Research output: Contribution to journalArticle

  3. De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia

    Hyrenius-Wittsten, A., Pilheden, M., Sturesson, H., Hansson, J., Walsh, M. P., Song, G., Kazi, J. U., Liu, J., Ramakrishan, R., Garcia-Ruiz, C., Nance, S., Gupta, P., Zhang, J., Rönnstrand, L., Hultquist, A., Downing, J. R., Lindkvist-Petersson, K., Paulsson, K., Järås, M., Gruber, T. A. & 2 othersMa, J. & Anna K. Hagström-Andersson, 2018 Dec 1, In : Nature Communications. 9, 1, 1770.

    Research output: Contribution to journalArticle

  4. Bruton’s tyrosine kinase potentiates ALK signaling and serves as a potential therapeutic target of neuroblastoma

    Li, T., Deng, Y., Shi, Y., Tian, R., Chen, Y., Zou, L., Julhash U. Kazi, Lars Rönnstrand, Feng, B., Chan, S. O., Chan, W. Y., Jianmin Sun & Zhao, H., 2018 Nov, In : Oncogene. 37, 47, p. 6180-6194

    Research output: Contribution to journalArticle

  5. The Src family kinase LCK cooperates with oncogenic FLT3/ITD in cellular transformation

    Marhäll, A., Julhash U. Kazi & Lars Rönnstrand, 2017 Dec 1, In : Scientific Reports. 7, 1, 13734.

    Research output: Contribution to journalArticle

  6. Efficacy of the CDK inhibitor dinaciclib in vitro and in vivo in T-cell acute lymphoblastic leukemia

    Sausan A. Moharram, Kinjal Shah, Khanum, F., Marhäll, A., Mohiuddin, G. & Julhash U. Kazi, 2017 Oct 1, In : Cancer Letters. 405, p. 73-78 6 p.

    Research output: Contribution to journalArticle

  7. KITD816V induces SRC-mediated tyrosine phosphorylation of MITF and altered transcription program in melanoma

    Bengt Phung, Julhash U. Kazi, Lundby, A., Bergsteinsdottir, K., Jianmin Sun, Goding, C. R., Jonsson, G., Olsen, J. V., Steingrímsson, E. & Lars Ronnstrand, 2017 Sep 1, In : Molecular Cancer Research. 15, 9, p. 1265-1274 10 p.

    Research output: Contribution to journalArticle

  8. The dual specificity PI3K/mTOR inhibitor PKI-587 displays efficacy against T-cell acute lymphoblastic leukemia (T-ALL)

    Mohiuddin, G., Sausan A. Moharram, Marhäll, A. & Julhash U. Kazi, 2017 Apr 28, In : Cancer Letters. 392, p. 9-16 8 p.

    Research output: Contribution to journalArticle

  9. ABL2 suppresses FLT3-ITD-induced cell proliferation through negative regulation of AKT signaling

    Julhash U Kazi, Rupar, K., Marhäll, A., Sausan A Moharram, Khanum, F., Kinjal Shah, Mohiuddin, G., Mysore Nagaraj, S. R., Jianmin Sun, Chougule, R. A. & Lars Rönnstrand, 2017, In : Oncotarget. 8, 7, p. 12194-12202

    Research output: Contribution to journalArticle

  10. Tyrosine 842 in the activation loop is required for full transformation by the oncogenic mutant FLT3-ITD

    Julhash U. Kazi, Chougule, R. A., Li, T., Su, X., Sausan A. Moharram, Rupar, K., Marhäll, A., Mohiuddin, G., Jianmin Sun, Zhao, H. & Lars Rönnstrand, 2017, In : Cellular and Molecular Life Sciences. 74, 14, p. 2679-2688

    Research output: Contribution to journalArticle

  11. Aberrant activation of the PI3K/mTOR pathway promotes resistance to sorafenib in AML

    O Lindblad, Cordero, E., Puissant, A., Macaulay, L., Ramos, A., Kabir, N. N., J Sun, J Vallon-Christersson, Haraldsson, K., Hemann, M. T., Åke Borg, F Levander, Stegmaier, K., K Pietras, L Rönnstrand & J U Kazi, 2016 Sep 29, In : Oncogene. 35, 39, p. 5119-5131 13 p.

    Research output: Contribution to journalArticle

  12. Src-like adaptor protein 2 (SLAP2) binds to and inhibits FLT3 signaling

    Sausan A Moharram, Chougule, R. A., Su, X., Li, T., Jianmin Sun, Zhao, H., Lars Rönnstrand & Julhash U Kazi, 2016 Jul 21, In : Oncotarget. p. 1-13 13 p.

    Research output: Contribution to journalArticle

  13. HIF2α contributes to antiestrogen resistance via positive bilateral crosstalk with EGFR in breast cancer cells.

    Alam, M. W., Persson, C., Reinbothe, S., Julhash U. Kazi, Lars Rönnstrand, Wigerup, C., Ditzel, H. J., Lykkesfeldt, A. E., Sven Påhlman & Annika Jögi, 2016 Mar, In : Oncotarget. 7, 10, p. 11238-50

    Research output: Contribution to journalArticle

  14. FYN expression potentiates FLT3-ITD induced STAT5 signaling in acute myeloid leukemia.

    Chougule, R. A., Julhash U. Kazi & Lars Rönnstrand, 2016, In : Oncotarget. 7, 9, p. 9964-9974

    Research output: Contribution to journalArticle

  15. Expression of GADS enhances FLT3-induced mitogenic signaling.

    Chougule, R. A., Cordero, E., Sausan A. Moharram, Kristian Pietras, Lars Rönnstrand & Julhash U. Kazi, 2016, In : Oncotarget. 7, 12, p. 14112-14124

    Research output: Contribution to journalArticle

  16. The role of HOXB2 and HOXB3 in acute myeloid leukemia.

    Oscar Lindblad, Chougule, R. A., Sausan A. Moharram, Kabir, N. N., Jianmin Sun, Julhash U. Kazi & Lars Rönnstrand, 2015, In : Biochemical and Biophysical Research Communications. 467, 4, p. 742-747

    Research output: Contribution to journalArticle

  17. BEX1 acts as a tumor suppressor in acute myeloid leukemia.

    Oscar Lindblad, Li, T., Su, X., Jianmin Sun, Kabir, N. N., Fredrik Levander, Zhao, H., Lu, G., Lars Rönnstrand & Julhash U. Kazi, 2015, In : Oncotarget. 6, 25, p. 21395-21405

    Research output: Contribution to journalArticle

  18. The Phosphatases STS1 and STS2 Regulate Hematopoietic Stem and Progenitor Cell Fitness.

    Zhang, J., Vakhrusheva, O., Bandi, S. R., Demirel, Ö., Julhash U. Kazi, Fernandes, R. G., Jakobi, K., Eichler, A., Lars Rönnstrand, Rieger, M. A., Carpino, N., Serve, H. & Brandts, C. H., 2015, In : Stem Cell Reports. 5, 4, p. 633-646

    Research output: Contribution to journalArticle

  19. Src-Like Adaptor Protein (SLAP) differentially regulates normal and oncogenic c-Kit signaling

    Julhash U. Kazi, Agarwal, S., Jianmin Sun, Baracco, E. & Lars Rönnstrand, 2014, In : Journal of Cell Science. 127, 3, p. 653-662

    Research output: Contribution to journalArticle

  20. SYK Is a Critical Regulator of FLT3 in Acute Myeloid Leukemia.

    Puissant, A., Fenouille, N., Alexe, G., Pikman, Y., Bassil, C. F., Mehta, S., Du, J., Julhash U. Kazi, Luciano, F., Lars Rönnstrand, Kung, A. L., Aster, J. C., Galinsky, I., Stone, R. M., Deangelo, D. J., Hemann, M. T. & Stegmaier, K., 2014, In : Cancer Cell. 25, 2, p. 226-242

    Research output: Contribution to journalArticle

  21. Keratin 19 expression correlates with poor prognosis in breast cancer

    Kabir, N. N., Lars Rönnstrand & Julhash U. Kazi, 2014, In : Molecular Biology Reports. 41, 12, p. 7729-7735

    Research output: Contribution to journalArticle

  22. Deregulation of protein phosphatase expression in acute myeloid leukemia

    Kabir, N. N., Lars Rönnstrand & Julhash U. Kazi, 2013, In : Medical Oncology. 30, 2

    Research output: Contribution to journalArticle

  23. Adaptor protein Lnk binds to and inhibits normal and leukemic FLT3

    Lin, D-C., Yin, T., Koren-Michowitz, M., Ding, L-W., Gueller, S., Gery, S., Tabayashi, T., Bergholz, U., Julhash U. Kazi, Lars Rönnstrand, Stocking, C. & Koeffler, H. P., 2012, In : Blood. 120, 16, p. 3310-3317

    Research output: Contribution to journalArticle

  24. Maximum likelihood analysis of mammalian p53 indicates the presence of positively selected sites and higher tumorigenic mutations in purifying sites

    Khan, M. M. G., Ryden, A. M., Chowdhury, M. S., Hasan, M. A. & Julhash U. Kazi, 2011, In : Gene. 483, 1-2, p. 29-35

    Research output: Contribution to journalArticle

  25. Comparative Studies on Human and Rat Basic Helix-loop-helix Proteins

    Kabir, N. N., Hossain, M. I. & Julhash U. Kazi, 2011, In : Asian Journal of Biological Sciences. p. 601-608

    Research output: Contribution to journalArticle

  26. Visualization of the melanosome transfer-inhibition in a mouse epidermal cell co-culture model.

    Kim, H. J., Julhash U. Kazi, Lee, Y. R., Nguyen, D. H., Lee, H. B., Shin, J. H., Soh, J. W. & Kim, E. K., 2010 Feb 1, In : International Journal of Molecular Medicine. 25, 2, p. 249-253

    Research output: Contribution to journalArticle

  27. Subcellular Localization of Diacylglycerol-responsive Protein Kinase C Isoforms in HeLa Cells

    Julhash U. Kazi, Kim, C. R. & Soh, J. W., 2009 Jan 31, In : Bulletin of the Korean Chemical Society. 30, 9, p. 1981-1984

    Research output: Contribution to journalArticle

  28. Role of Regulatory Domain Mutants of PKC Isoforms in c-fos Induction

    Julhash U. Kazi & Soh, J. W., 2008 Dec 31, In : Bulletin of the Korean Chemical Society. 29, 1, p. 252-254

    Research output: Contribution to journalArticle

  29. Induction of the nuclear proto-oncogene c-fos by the phorbol ester TPA and v-H-Ras.

    Julhash U. Kazi & Soh, J. W., 2008 Nov 30, In : Molecules and Cells. 26, 5, p. 462-467

    Research output: Contribution to journalArticle

  30. Celecoxib-induced growth inhibition in SW480 colon cancer cells is associated with activation of protein kinase G

    Soh, J. W., Julhash U. Kazi, Li, H., Thompson, W. J. & Weinstein, I. B., 2008 Jul 1, In : Molecular Carcinogenesis. 47, 7, p. 519-525

    Research output: Contribution to journalArticle

  31. Bioinformatic prediction and analysis of eukaryotic protein kinases in the rat genome.

    Julhash U. Kazi, Kabir, N. N. & Soh, J. W., 2008, In : Gene. 410(1), Feb,29, p. 147-153

    Research output: Contribution to journalArticle

  32. Isoform-specific translocation of PKC isoforms in NIH3T3 cells by TPA.

    Julhash U. Kazi & Soh, J. W., 2007 Dec 14, In : Biochemical and Biophysical Research Communications. 364, 2, p. 231-237

    Research output: Contribution to journalArticle

  33. Letter
  34. The basic helix-loop-helix (bHLH) proteins in breast cancer progression

    Kabir, N. N., Lars Rönnstrand & Julhash U. Kazi, 2013, In : Medical Oncology. 30, 3

    Research output: Contribution to journalLetter

  35. FLT3 mutations in patients with childhood acute lymphoblastic leukemia (ALL)

    Kabir, N. N., Lars Rönnstrand & Julhash U. Kazi, 2013, In : Medical Oncology. 30, 1, p. 462-462

    Research output: Contribution to journalLetter

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