Kazi Uddin

Associate Researcher, Docent, PhDKnown as name: Julhash U. Kazi
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  1. 2019
  2. The role of SRC family kinases in FLT3 signaling

    Julhash U. Kazi & Lars Rönnstrand, 2019 Feb 1, In : International Journal of Biochemistry and Cell Biology. 107, p. 32-37 6 p.

    Research output: Contribution to journalReview article

  3. FMS-like Tyrosine Kinase 3/FLT3: From Basic Science to Clinical Implications

    Julhash U. Kazi & Lars Rönnstrand, 2019, In : Physiological Reviews. 99, 3, p. 1433-1466 34 p.

    Research output: Contribution to journalArticle

  4. 2018
  5. De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia

    Hyrenius-Wittsten, A., Pilheden, M., Sturesson, H., Hansson, J., Walsh, M. P., Song, G., Kazi, J. U., Liu, J., Ramakrishan, R., Garcia-Ruiz, C., Nance, S., Gupta, P., Zhang, J., Rönnstrand, L., Hultquist, A., Downing, J. R., Lindkvist-Petersson, K., Paulsson, K., Järås, M., Gruber, T. A. & 2 othersMa, J. & Anna K. Hagström-Andersson, 2018 Dec 1, In : Nature Communications. 9, 1, 1770.

    Research output: Contribution to journalArticle

  6. Bruton’s tyrosine kinase potentiates ALK signaling and serves as a potential therapeutic target of neuroblastoma

    Li, T., Deng, Y., Shi, Y., Tian, R., Chen, Y., Zou, L., Julhash U. Kazi, Lars Rönnstrand, Feng, B., Chan, S. O., Chan, W. Y., Jianmin Sun & Zhao, H., 2018 Nov, In : Oncogene. 37, 47, p. 6180-6194

    Research output: Contribution to journalArticle

  7. 2017
  8. The Src family kinase LCK cooperates with oncogenic FLT3/ITD in cellular transformation

    Marhäll, A., Julhash U. Kazi & Lars Rönnstrand, 2017 Dec 1, In : Scientific Reports. 7, 1, 13734.

    Research output: Contribution to journalArticle

  9. Efficacy of the CDK inhibitor dinaciclib in vitro and in vivo in T-cell acute lymphoblastic leukemia

    Sausan A. Moharram, Kinjal Shah, Khanum, F., Marhäll, A., Mohiuddin, G. & Julhash U. Kazi, 2017 Oct 1, In : Cancer Letters. 405, p. 73-78 6 p.

    Research output: Contribution to journalArticle

  10. KITD816V induces SRC-mediated tyrosine phosphorylation of MITF and altered transcription program in melanoma

    Bengt Phung, Julhash U. Kazi, Lundby, A., Bergsteinsdottir, K., Jianmin Sun, Goding, C. R., Jonsson, G., Olsen, J. V., Steingrímsson, E. & Lars Ronnstrand, 2017 Sep 1, In : Molecular Cancer Research. 15, 9, p. 1265-1274 10 p.

    Research output: Contribution to journalArticle

  11. The dual specificity PI3K/mTOR inhibitor PKI-587 displays efficacy against T-cell acute lymphoblastic leukemia (T-ALL)

    Mohiuddin, G., Sausan A. Moharram, Marhäll, A. & Julhash U. Kazi, 2017 Apr 28, In : Cancer Letters. 392, p. 9-16 8 p.

    Research output: Contribution to journalArticle

  12. BEX3

    Julhash U. Kazi, Kabir, N. N. & Lars Rönnstrand, 2017 Feb 11, Encyclopedia of Signaling Molecules. Choi, S. (ed.). Springer New York, p. 1-4 4 p.

    Research output: Chapter in Book/Report/Conference proceedingEntry for encyclopedia/dictionary

  13. ABL2 suppresses FLT3-ITD-induced cell proliferation through negative regulation of AKT signaling

    Julhash U Kazi, Rupar, K., Marhäll, A., Sausan A Moharram, Khanum, F., Kinjal Shah, Mohiuddin, G., Mysore Nagaraj, S. R., Jianmin Sun, Chougule, R. A. & Lars Rönnstrand, 2017, In : Oncotarget. 8, 7, p. 12194-12202

    Research output: Contribution to journalArticle

  14. Tyrosine 842 in the activation loop is required for full transformation by the oncogenic mutant FLT3-ITD

    Julhash U. Kazi, Chougule, R. A., Li, T., Su, X., Sausan A. Moharram, Rupar, K., Marhäll, A., Mohiuddin, G., Jianmin Sun, Zhao, H. & Lars Rönnstrand, 2017, In : Cellular and Molecular Life Sciences. 74, 14, p. 2679-2688

    Research output: Contribution to journalArticle

  15. 2016
  16. Src-Like Adapter Protein 2 (SLAP2)

    Sausan A. Moharram, Lars Rönnstrand & Julhash U. Kazi, 2016 Dec 24, Encyclopedia of Signaling Molecules. Choi, S. (ed.). Springer New York, Vol. 2. p. 1-4

    Research output: Chapter in Book/Report/Conference proceedingEntry for encyclopedia/dictionary

  17. Src-Like Adapter Protein (SLAP)

    Sausan A. Moharram, Lars Rönnstrand & Julhash U. Kazi, 2016 Dec 24, Encyclopedia of Signaling Molecules. Choi, S. (ed.). Springer New York, p. 1-4 4 p.

    Research output: Chapter in Book/Report/Conference proceedingEntry for encyclopedia/dictionary

  18. FMS-Like Tyrosine Kinase-3

    Julhash U. Kazi, Sausan A. Moharram & Lars Rönnstrand, 2016 Dec 20, Encyclopedia of Signaling Molecules. Choi, S. (ed.). 2nd ed. Springer New York, p. 1-4

    Research output: Chapter in Book/Report/Conference proceedingEntry for encyclopedia/dictionary

  19. GRB10

    Kabir, N. N., Lars Rönnstrand & Julhash U. Kazi, 2016 Dec 20, Encyclopedia of Signaling Molecules. Choi, S. (ed.). 2nd ed. Springer New York, p. 1-4

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

  20. Kit

    Rupar, K., Julhash U. Kazi & Lars Rönnstrand, 2016 Nov 29, Encyclopedia of Signaling Molecules. Choi, S. (ed.). 2nd ed. Springer New York, p. 1-5

    Research output: Chapter in Book/Report/Conference proceedingEntry for encyclopedia/dictionary

  21. Germline mutations of KIT in gastrointestinal stromal tumor (GIST) and mastocytosis

    Ke, H., Julhash U. Kazi, Zhao, H. & Jianmin Sun, 2016 Oct 18, In : Cell and Bioscience. 6, 1, 55.

    Research output: Contribution to journalReview article

  22. Aberrant activation of the PI3K/mTOR pathway promotes resistance to sorafenib in AML

    O Lindblad, Cordero, E., Puissant, A., Macaulay, L., Ramos, A., Kabir, N. N., J Sun, J Vallon-Christersson, Haraldsson, K., Hemann, M. T., Åke Borg, F Levander, Stegmaier, K., K Pietras, L Rönnstrand & J U Kazi, 2016 Sep 29, In : Oncogene. 35, 39, p. 5119-5131 13 p.

    Research output: Contribution to journalArticle

  23. Src-like adaptor protein 2 (SLAP2) binds to and inhibits FLT3 signaling

    Sausan A Moharram, Chougule, R. A., Su, X., Li, T., Jianmin Sun, Zhao, H., Lars Rönnstrand & Julhash U Kazi, 2016 Jul 21, In : Oncotarget. p. 1-13 13 p.

    Research output: Contribution to journalArticle

  24. HIF2α contributes to antiestrogen resistance via positive bilateral crosstalk with EGFR in breast cancer cells.

    Alam, M. W., Persson, C., Reinbothe, S., Julhash U. Kazi, Lars Rönnstrand, Wigerup, C., Ditzel, H. J., Lykkesfeldt, A. E., Sven Påhlman & Annika Jögi, 2016 Mar, In : Oncotarget. 7, 10, p. 11238-50

    Research output: Contribution to journalArticle

  25. Expression of GADS enhances FLT3-induced mitogenic signaling.

    Chougule, R. A., Cordero, E., Sausan A. Moharram, Kristian Pietras, Lars Rönnstrand & Julhash U. Kazi, 2016, In : Oncotarget. 7, 12, p. 14112-14124

    Research output: Contribution to journalArticle

  26. FYN expression potentiates FLT3-ITD induced STAT5 signaling in acute myeloid leukemia.

    Chougule, R. A., Julhash U. Kazi & Lars Rönnstrand, 2016, In : Oncotarget. 7, 9, p. 9964-9974

    Research output: Contribution to journalArticle

  27. 2015
  28. Bone Marrow Transplants

    Oscar Lindblad, Julhash U. Kazi & Lars Rönnstrand, 2015 Sep 22, The SAGE Encyclopedia of Stem Cell Research. Bouhassira, E. E. (ed.). Thousand Oaks: SAGE Publications Inc., p. 129-132 7 p.

    Research output: Chapter in Book/Report/Conference proceedingEntry for encyclopedia/dictionary

  29. Drug Testing and Drug Development in Cell Culture

    Julhash U. Kazi, Kabir, N. N. & Lars Rönnstrand, 2015 Sep 22, The SAGE Encyclopedia of Stem Cell Research. Bouhassira, E. E. (ed.). SAGE Publications Inc., p. 363-366

    Research output: Chapter in Book/Report/Conference proceedingEntry for encyclopedia/dictionary

  30. Fluorescence-Activated Cell Sorting

    Julhash U. Kazi, Jianmin Sun & Lars Rönnstrand, 2015 Sep 22, The SAGE Encyclopedia of Stem Cell Research. Bouhassira, E. E. (ed.). SAGE Publications Inc., p. 418-420

    Research output: Chapter in Book/Report/Conference proceedingEntry for encyclopedia/dictionary

  31. BEX1 acts as a tumor suppressor in acute myeloid leukemia.

    Oscar Lindblad, Li, T., Su, X., Jianmin Sun, Kabir, N. N., Fredrik Levander, Zhao, H., Lu, G., Lars Rönnstrand & Julhash U. Kazi, 2015, In : Oncotarget. 6, 25, p. 21395-21405

    Research output: Contribution to journalArticle

  32. Brain-Expressed X-linked (BEX) proteins in human cancers.

    Julhash U. Kazi, Kabir, N. N. & Lars Rönnstrand, 2015, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1856, 2, p. 226-233

    Research output: Contribution to journalReview article

  33. Role of SRC-like adaptor protein (SLAP) in immune and malignant cell signaling.

    Julhash U. Kazi, Kabir, N. N. & Lars Rönnstrand, 2015, In : Cellular and Molecular Life Sciences. 72, 13, p. 2535-2544

    Research output: Contribution to journalReview article

  34. SOCS6 (suppressor of cytokine signaling 6)

    Julhash U. Kazi, Flores-Morales, A. & Lars Rönnstrand, 2015, In : Atlas of Genetics and Cytogenetics in Oncology and Haematology. 19, 1, p. 50-52

    Research output: Contribution to journalReview article

  35. The Phosphatases STS1 and STS2 Regulate Hematopoietic Stem and Progenitor Cell Fitness.

    Zhang, J., Vakhrusheva, O., Bandi, S. R., Demirel, Ö., Julhash U. Kazi, Fernandes, R. G., Jakobi, K., Eichler, A., Lars Rönnstrand, Rieger, M. A., Carpino, N., Serve, H. & Brandts, C. H., 2015, In : Stem Cell Reports. 5, 4, p. 633-646

    Research output: Contribution to journalArticle

  36. The role of HOXB2 and HOXB3 in acute myeloid leukemia.

    Oscar Lindblad, Chougule, R. A., Sausan A. Moharram, Kabir, N. N., Jianmin Sun, Julhash U. Kazi & Lars Rönnstrand, 2015, In : Biochemical and Biophysical Research Communications. 467, 4, p. 742-747

    Research output: Contribution to journalArticle

  37. 2014
  38. Grb10 is a dual regulator of receptor tyrosine kinase signaling

    Kabir, N. N. & Julhash U. Kazi, 2014, In : Molecular Biology Reports. 41, 4, p. 1985-1992

    Research output: Contribution to journalReview article

  39. Keratin 19 expression correlates with poor prognosis in breast cancer

    Kabir, N. N., Lars Rönnstrand & Julhash U. Kazi, 2014, In : Molecular Biology Reports. 41, 12, p. 7729-7735

    Research output: Contribution to journalArticle

  40. SOCS6 is a selective suppressor of receptor tyrosine kinase signaling

    Kabir, N. N., Jianmin Sun, Lars Rönnstrand & Julhash U. Kazi, 2014, In : Tumor Biology. 35, 11, p. 10581-10589

    Research output: Contribution to journalReview article

  41. SOCS proteins in regulation of receptor tyrosine kinase signaling.

    Julhash U. Kazi, Kabir, N. N., Flores-Morales, A. & Lars Rönnstrand, 2014, In : Cellular and Molecular Life Sciences. 71, 17, p. 3297-3310

    Research output: Contribution to journalReview article

  42. Src-Like Adaptor Protein (SLAP) differentially regulates normal and oncogenic c-Kit signaling

    Julhash U. Kazi, Agarwal, S., Jianmin Sun, Baracco, E. & Lars Rönnstrand, 2014, In : Journal of Cell Science. 127, 3, p. 653-662

    Research output: Contribution to journalArticle

  43. SYK Is a Critical Regulator of FLT3 in Acute Myeloid Leukemia.

    Puissant, A., Fenouille, N., Alexe, G., Pikman, Y., Bassil, C. F., Mehta, S., Du, J., Julhash U. Kazi, Luciano, F., Lars Rönnstrand, Kung, A. L., Aster, J. C., Galinsky, I., Stone, R. M., Deangelo, D. J., Hemann, M. T. & Stegmaier, K., 2014, In : Cancer Cell. 25, 2, p. 226-242

    Research output: Contribution to journalArticle

  44. 2013
  45. Deregulation of protein phosphatase expression in acute myeloid leukemia

    Kabir, N. N., Lars Rönnstrand & Julhash U. Kazi, 2013, In : Medical Oncology. 30, 2

    Research output: Contribution to journalArticle

  46. FLT3 mutations in patients with childhood acute lymphoblastic leukemia (ALL)

    Kabir, N. N., Lars Rönnstrand & Julhash U. Kazi, 2013, In : Medical Oncology. 30, 1, p. 462-462

    Research output: Contribution to journalLetter

  47. Protein kinase C expression is deregulated in chronic lymphocytic leukemia

    Kabir, N. N., Lars Rönnstrand & Julhash U. Kazi, 2013, In : Leukemia & Lymphoma. 54, 10, p. 2288-2290

    Research output: Contribution to journalLetter

  48. Protein kinase C (PKC) as a drug target in chronic lymphocytic leukemia.

    Julhash U. Kazi, Kabir, N. N. & Lars Rönnstrand, 2013, In : Medical Oncology. 30, 4, p. 757

    Research output: Contribution to journalReview article

  49. The basic helix-loop-helix (bHLH) proteins in breast cancer progression

    Kabir, N. N., Lars Rönnstrand & Julhash U. Kazi, 2013, In : Medical Oncology. 30, 3

    Research output: Contribution to journalLetter

  50. 2012
  51. Adaptor protein Lnk binds to and inhibits normal and leukemic FLT3

    Lin, D-C., Yin, T., Koren-Michowitz, M., Ding, L-W., Gueller, S., Gery, S., Tabayashi, T., Bergholz, U., Julhash U. Kazi, Lars Rönnstrand, Stocking, C. & Koeffler, H. P., 2012, In : Blood. 120, 16, p. 3310-3317

    Research output: Contribution to journalArticle

  52. 2011
  53. Comparative Studies on Human and Rat Basic Helix-loop-helix Proteins

    Kabir, N. N., Hossain, M. I. & Julhash U. Kazi, 2011, In : Asian Journal of Biological Sciences. p. 601-608

    Research output: Contribution to journalArticle

  54. Maximum likelihood analysis of mammalian p53 indicates the presence of positively selected sites and higher tumorigenic mutations in purifying sites

    Khan, M. M. G., Ryden, A. M., Chowdhury, M. S., Hasan, M. A. & Julhash U. Kazi, 2011, In : Gene. 483, 1-2, p. 29-35

    Research output: Contribution to journalArticle

  55. The mechanism of protein kinase C regulation

    Julhash U. Kazi, 2011, In : Frontiers in Biology. 6, 4, p. 328-336

    Research output: Contribution to journalReview article

  56. 2010
  57. Visualization of the melanosome transfer-inhibition in a mouse epidermal cell co-culture model.

    Kim, H. J., Julhash U. Kazi, Lee, Y. R., Nguyen, D. H., Lee, H. B., Shin, J. H., Soh, J. W. & Kim, E. K., 2010 Feb 1, In : International Journal of Molecular Medicine. 25, 2, p. 249-253

    Research output: Contribution to journalArticle

  58. 2009
  59. Subcellular Localization of Diacylglycerol-responsive Protein Kinase C Isoforms in HeLa Cells

    Julhash U. Kazi, Kim, C. R. & Soh, J. W., 2009 Jan 31, In : Bulletin of the Korean Chemical Society. 30, 9, p. 1981-1984

    Research output: Contribution to journalArticle

  60. 2008
  61. Role of Regulatory Domain Mutants of PKC Isoforms in c-fos Induction

    Julhash U. Kazi & Soh, J. W., 2008 Dec 31, In : Bulletin of the Korean Chemical Society. 29, 1, p. 252-254

    Research output: Contribution to journalArticle

  62. Induction of the nuclear proto-oncogene c-fos by the phorbol ester TPA and v-H-Ras.

    Julhash U. Kazi & Soh, J. W., 2008 Nov 30, In : Molecules and Cells. 26, 5, p. 462-467

    Research output: Contribution to journalArticle

  63. Celecoxib-induced growth inhibition in SW480 colon cancer cells is associated with activation of protein kinase G

    Soh, J. W., Julhash U. Kazi, Li, H., Thompson, W. J. & Weinstein, I. B., 2008 Jul 1, In : Molecular Carcinogenesis. 47, 7, p. 519-525

    Research output: Contribution to journalArticle

  64. Bioinformatic prediction and analysis of eukaryotic protein kinases in the rat genome.

    Julhash U. Kazi, Kabir, N. N. & Soh, J. W., 2008, In : Gene. 410(1), Feb,29, p. 147-153

    Research output: Contribution to journalArticle

  65. 2007
  66. Isoform-specific translocation of PKC isoforms in NIH3T3 cells by TPA.

    Julhash U. Kazi & Soh, J. W., 2007 Dec 14, In : Biochemical and Biophysical Research Communications. 364, 2, p. 231-237

    Research output: Contribution to journalArticle