Kajsa Paulsson

Professor

Research areas and keywords

UKÄ subject classification

  • Cancer and Oncology

Keywords

  • aneuploidy, hyperdiploidy

Research

Aneuploidy in malignancies

Aberrant chromosome numbers – i.e. aneuploidy – is one of the most common characteristics of malignant cells. The overall aim of my research is to understand how aneuploidy arises in somatic cells, how it affects tumorigenesis, and how it correlates with prognosis and treatment response. In particular, my studies are focused on high hyperdiploid and hypodiploid childhood acute lymphoblastic leukemia. Ultimately, the goal is to use the new knowledge that we gain from these studies of the basis of tumorigenesis to improve the survival of cancer patients.

Professional work

Dr Paulsson is Professor of Medical Genetics and runs the Aneuploidy in Cancer research group at the Division of Clinical Genetics. She is an expert in cancer genomics and is experienced in classic genetic techniques such as chromosome analysis and fluorescence in situ hybridization as well as state-of-the-art SNP array analysis and next generation sequencing (NGS).

Highlighted research outputs

Minjun Yang, Setareh Safavi, Eleanor L Woodward, Nicolas Duployez, Linda Olsson-arvidsson, Jonas Ungerbäck, Mikael Sigvardsson, Marketa Zaliova, Jan Zuna, Thoas Fioretos, Bertil Johansson, Karolin H Nord & Kajsa Paulsson, 2020 Aug 20, In: Blood. 136, 8, p. 946-956 11 p.

Research output: Contribution to journalArticle

Minjun Yang, Mattias Vesterlund, Ioannis Siavelis, Larissa H. Moura-Castro, Anders Castor, Thoas Fioretos, Rozbeh Jafari, Henrik Lilljebjörn, Duncan T. Odom, Linda Olsson, Naveen Ravi, Eleanor L. Woodward, Louise Harewood, Janne Lehtiö & Kajsa Paulsson, 2019 Apr 3, In: Nature Communications. 10, 1, 1519.

Research output: Contribution to journalArticle

Kajsa Paulsson & Ponte di Legno Childhood ALL Working Group Ponte di Legno Childhood ALL Working Group, 2019 Apr 1, In: Journal of Clinical Oncology. 37, 10, p. 770-779 10 p.

Research output: Contribution to journalArticle

Kajsa Paulsson, Henrik Lilljebjörn, Andrea Biloglav, Linda Olsson, Marianne Rissler, Anders Castor, Gisela Barbany, Linda Fogelstrand, Ann Nordgren, Helene Sjögren, Thoas Fioretos & Bertil Johansson, 2015, In: Nature Genetics. 47, 6, p. 672-676

Research output: Contribution to journalArticle

Naveen Ravi, Minjun Yang, Sigurdur Gretarsson, Caroline Jansson, Nektaria Mylona, Saskia R. Sydow, Eleanor L. Woodward, Lars Ekblad, Johan Wennerberg & Kajsa Paulsson, 2019 Mar 22, In: Cancers. 11, 3, 402.

Research output: Contribution to journalArticle

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