Kajsa Paulsson

Senior Lecturer, Associate Professor

Research areas and keywords

UKÄ subject classification

  • Cancer and Oncology

Keywords

  • aneuploidy, hyperdiploidy

Research

Aneuploidy in malignancies

An aberrant number of chromosomes – i.e. aneuploidy – is one of the most common characteristics of malignant cells. The overall aim of my research is to understand how aneuploidy arises in somatic cells, how it affects tumorigenesis, and how it correlates with prognosis and treatment response. In particular, my studies are focused on high hyperdiploid and hypodiploid childhood acute lymphoblastic leukemia. Ultimately, the goal is to use the new knowledge that we gain from these studies of the basis of tumorigenesis to improve the survival of cancer patients.

Professional work

Dr Paulsson is Associate Professor of Experimental Clinical Genetics and runs the Aneuploidy in Cancer research group at the Division of Clinical Genetics. She is an expert in cancer genomics and is experienced in classic genetic techniques such as chromosome analysis and fluorescence in situ hybridization as well as state-of-the-art SNP array analysis and next generation sequencing (NGS).

Highlighted research outputs

Minjun Yang, Vesterlund, M., Siavelis, I., Moura-Castro, L. H., Anders Castor, Thoas Fioretos, Jafari, R., Henrik Lilljebjörn, Odom, D. T., Linda Olsson, Naveen Ravi, Eleanor L. Woodward, Harewood, L., Lehtiö, J. & Kajsa Paulsson, 2019 Apr 3, In : Nature Communications. 10, 1, 1519.

Research output: Contribution to journalArticle

Naveen Ravi, Minjun Yang, Sigurdur Gretarsson, Jansson, C., Mylona, N., Sydow, S. R., Eleanor L. Woodward, Lars Ekblad, Johan Wennerberg & Kajsa Paulsson, 2019 Mar 22, In : Cancers. 11, 3, 402.

Research output: Contribution to journalArticle

Studd, J. B., Vijayakrishnan, J., Minjun Yang, Migliorini, G., Kajsa Paulsson & Houlston, R. S., 2017 Mar 3, In : Nature Communications. 8, 14616.

Research output: Contribution to journalArticle

Kajsa Paulsson, Henrik Lilljebjörn, Biloglav, A., Linda Olsson, Rissler, M., Anders Castor, Barbany, G., Fogelstrand, L., Nordgren, A., Sjögren, H., Thoas Fioretos & Bertil Johansson, 2015, In : Nature Genetics. 47, 6, p. 672-676

Research output: Contribution to journalArticle

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