Lena Eliasson

Professor
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  1. 2019
  2. Defective exocytosis and processing of insulin in a cystic fibrosis mouse model

    Anna Edlund, Mohammad Barghouth, Huhn, M., Abels, M., Jonathan Esguerra, Ines Mollet, Svedin, E., Anna Wendt, Erik Renström, Enming Zhang, Nils Wierup, Scholte, B. J., Flodström-Tullberg, M. & Lena Eliasson, 2019, In : Journal of Endocrinology. 241, 1, p. 45-57

    Research output: Contribution to journalArticle

  3. In Vivo Silencing of MicroRNA-132 Reduces Blood Glucose and Improves Insulin Secretion

    Bijkerk, R., Jonathan L S Esguerra, Ellenbroek, J. H., Au, Y. W., Hanegraaf, M. A. J., de Koning, E. J., Lena Eliasson & van Zonneveld, A. J., 2019, In : Nucleic acid therapeutics. 29, 2, p. 67-72

    Research output: Contribution to journalArticle

  4. 2018
  5. Islet microRNAs in health and type-2 diabetes

    Anna Wendt, Jonathan LS Esguerra & Lena Eliasson, 2018 Dec 1, In : Current Opinion in Pharmacology. 43, p. 46-52 7 p.

    Research output: Contribution to journalReview article

  6. N1-methylnicotinamide is a signalling molecule produced in skeletal muscle coordinating energy metabolism

    Ström, K., Morales-Alamo, D., Ottosson, F., Edlund, A., Hjort, L., Jörgensen, S. W., Almgren, P., Zhou, Y., Martin-Rincon, M., Ekman, C., Pérez-López, A., Ekström, O., Perez-Suarez, I., Mattiasson, M., De Pablos-Velasco, P., Oskolkov, N., Ahlqvist, E., Wierup, N., Eliasson, L., Vaag, A. & 6 othersLeif Groop, Karin G. Stenkula, Céline Fernandez, Calbet, J. A. L., Holmberg, H. C. & Ola Hansson, 2018 Dec 1, In : Scientific Reports. 8, 1, 3016.

    Research output: Contribution to journalArticle

  7. MicroRNAs in islet hormone secretion

    Jonathan L.S. Esguerra, Mototsugu Nagao, Jones K. Ofori, Anna Wendt & Lena Eliasson, 2018 Sep 1, In : Diabetes, Obesity and Metabolism. 20, Suppl 2, p. 11-19

    Research output: Contribution to journalReview article

  8. She is in science to stay!

    Birnir, B. & L. Eliasson, 2018, In : Acta Physiologica. 223, 1, p. e13048

    Research output: Contribution to journalDebate/Note/Editorial

  9. 2017
  10. MiR-335 overexpression impairs insulin secretion through defective priming of insulin vesicles

    Salunkhe, V. A., Jones K. Ofori, Gandasi, N. R., Salö, S. A., Hansson, S., Markus E. Andersson, Anna Wendt, Barg, S., Jonathan L.S. Esguerra & Lena Eliasson, 2017 Nov 1, In : Physiological Reports. 5, 21, e13493.

    Research output: Contribution to journalArticle

  11. Glucotoxicity-induced upregulation of lincRNA GAS5 in the pancreatic islets of type 2 diabetes donors and in Goto-Kakizaki rats

    J. L. S. Esguerra, J. Ofori, M. Nagao, Fadista, J., L. Groop & L. Eliasson, 2017 Sep 1, In : Diabetologia. 60, 1 Suppl 1, p. S22-S23

    Research output: Contribution to journalPublished meeting abstract

  12. Reduced insulin secretion in a diet-induced glucose intolerance susceptible mouse model is coupled with increased CD36 and triglycerides in the beta cells

    A. Asai, M. Nagao, Tsuduki, T., Miyazawa, T., J. L. S. Esguerra, L. Eliasson, Sugihara, H. & Oikawa, S., 2017 Sep 1, p. S61.

    Research output: Contribution to conferenceAbstract

  13. An 'alpha-beta' of pancreatic islet microribonucleotides

    Dalgaard, L. T. & Lena Eliasson, 2017 Jul, In : International Journal of Biochemistry and Cell Biology. 88, p. 208-219

    Research output: Contribution to journalArticle

  14. Mitochondrial transcription factor B2 is essential for mitochondrial and cellular function in pancreatic β-cells

    Nicholas, L. M., Valtat, B., Benavente, A. M., Andersson, L., Abels, M., Ines Mollet, Jain, D., Lena Eliasson, Nils Wierup, Malin Fex & Hindrik Mulder, 2017 Jul, In : Molecular Metabolism. 6, 7, p. 651-663 13 p.

    Research output: Contribution to journalArticle

  15. Sox5 regulates beta-cell phenotype and is reduced in type 2 diabetes

    Axelsson, A., Mahdi, T., Nenonen, H. A., Singh, T., Hänzelmann, S., Wendt, A., Bagge, A., Reinbothe, T. M., Millstein, J., Yang, X., Zhang, B., Gusmao, E. G., Shu, L., Szabat, M., Tang, Y., Wang, J., Salö, S., Eliasson, L., Artner, I., Fex, M. & 9 othersJ D Johnson, C B Wollheim, Derry, J. M. J., Mecham, B., P Spégel, H Mulder, Costa, I. G., E Zhang & Rosengren, A. H., 2017 Jun 6, In : Nature Communications. 8, p. 15652

    Research output: Contribution to journalArticle

  16. Reduced blood glucose through thyroid hormone degradation product

    L. Eliasson, 2017 Jun 1, In : Acta Physiologica. 220, 2, p. 184-185 2 p.

    Research output: Contribution to journalArticle

  17. CFTR is involved in the regulation of glucagon secretion in human and rodent alpha cells

    Anna Edlund, Pedersen, M. G., Andreas Lindqvist, Nils Wierup, Flodström-Tullberg, M. & Lena Eliasson, 2017 Mar 7, In : Scientific Reports. 7, p. 1-12 90.

    Research output: Contribution to journalArticle

  18. Erythropoietin and TRPV1 together in new formation

    L. Eliasson, 2017 Feb 1, In : Acta Physiologica. 219, 2, p. 341-342 2 p.

    Research output: Contribution to journalDebate/Note/Editorial

  19. HDAC7 is overexpressed in human diabetic islets and impairs insulin secretion in rat islets and clonal beta cells

    Daneshpajooh, M., Karl Bacos, Bysani, M., Bagge, A., Ottosson Laakso, E., Petter Vikman, Lena Eliasson, Hindrik Mulder & Charlotte Ling, 2017 Jan, In : Diabetologia. 60, 1, p. 116–125

    Research output: Contribution to journalArticle

  20. Endogenous beta-cell CART regulates insulin secretion and transcription of beta-cell genes

    L Shcherbina, A Edlund, J L S Esguerra, Abels, M., Zhou, Y., Ottosson-Laakso, E., C B Wollheim, O Hansson, L Eliasson & N Wierup, 2017, In : Molecular and Cellular Endocrinology. 447, p. 52-60

    Research output: Contribution to journalArticle

  21. Identification of islet-enriched long non-coding RNAs contributing to β-cell failure in type 2 diabetes

    Motterle, A., Gattesco, S., Peyot, M. L., Jonathan Lou S. Esguerra, Ruiz-Gomez, A., Laybutt, D. R., Gilon, P., Burdet, F., Ibberson, M., Lena Eliasson, Prentki, M. & Regazzi, R., 2017, In : Molecular Metabolism. 6, 11, p. 1407-1418

    Research output: Contribution to journalArticle

  22. Neuron-enriched RNA-binding Proteins Regulate Pancreatic Beta Cell Function and Survival

    Juan-Mateu, J. A., Rech, T. H., Villate, O., Lizarraga-Mollinedo, E., Anna Wendt, Turatsinze, J-V., Brondani, L. A., Nardelli, T. R., Nogueira, T. C., Jonathan Esguerra, Alvelos, M. I. E., Marchetti, P., Lena Eliasson & Eizirik, D. E. L., 2017, In : Journal of Biological Chemistry. 292, 8, p. 3466-3480

    Research output: Contribution to journalArticle

  23. PIWI-interacting RNAs as novel regulators of pancreatic beta cell function

    Henaoui, I. S., Jacovetti, C., Ines Mollet, Guay, C., Sobel, J., Lena Eliasson & Regazzi, R., 2017, In : Diabetologia. 60, 10, p. 1977-1986

    Research output: Contribution to journalArticle

  24. 2016
  25. Dual Effect of Rosuvastatin on Glucose Homeostasis Through Improved Insulin Sensitivity and Reduced Insulin Secretion

    Salunkhe, V. A., Ines Mollet, Jones K. Ofori, Malm, H. A., Jonathan L S Esguerra, Reinbothe, T., Karin G. Stenkula, Anna Wendt, Lena Eliasson & Vikman, J., 2016 Aug, In : EBioMedicine. 10, p. 185-194

    Research output: Contribution to journalArticle

  26. Diabetes: Partners for life

    Lena Eliasson & Anna Wendt, 2016 May 18, In : eLife. 5, p. 1-2 e16798.

    Research output: Contribution to journalArticle

  27. Rosuvastatin treatment affects both basal and glucose-induced insulin secretion in INS-1 832/13 cells

    Salunkhe, V. A., Olof Elvstam, Lena Eliasson & Anna Wendt, 2016 Mar 1, In : PLoS ONE. 11, 3, e0151592.

    Research output: Contribution to journalArticle

  28. Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes

    Karl Bacos, Gillberg, L., Petr Volkov, Olsson, A. H., Hansen, T., Pedersen, O., Gjesing, A. P., Eiberg, H., Tuomi, T., Almgren, P., Leif Groop, Lena Eliasson, Allan Vaag, Dayeh, T. & Charlotte Ling, 2016, In : Nature Communications. 7, 11089.

    Research output: Contribution to journalArticle

  29. Serotonin (5-HT) receptor 2b activation augments glucose-stimulated insulin secretion in human and mouse islets of Langerhans.

    Bennet, H., Ines Mollet, Balhuizen, A., Medina Benavente, A., Nagorny, C., Bagge, A., Fadista, J., Ottosson Laakso, E., Petter Vikman, Dekker Nitert, M., Lena Eliasson, Nils Wierup, Isabella Artner & Malin Fex, 2016, In : Diabetologia. 59, 4, p. 744-754

    Research output: Contribution to journalArticle

  30. 2015
  31. MiR-335 regulates exocytotic proteins and affects glucose-stimulated insulin secretion through decreased Ca2+-dependent exocytosis in beta cells

    Salunkhe, V. A., J. Ofori, Gandasi, N. R., Salö, S. A., A. Wendt, Barg, S., J.L.S. Esguerra & L. Eliasson, 2015 Sep 1, In : Diabetologia. 58, Suppl. 1, p. S128 1 p.

    Research output: Contribution to journalPublished meeting abstract

  32. Bone morphogenetic protein 4 inhibits insulin secretion from rodent beta cells through regulation of calbindin1 expression and reduced voltage-dependent calcium currents

    Christensen, G. L., Jacobsen, M. L. B., Anna Wendt, Ines Mollet, Friberg, J., Frederiksen, K. S., Meyer, M., Bruun, C., Lena Eliasson & Billestrup, N., 2015, In : Diabetologia. 58, 6, p. 1282-1290

    Research output: Contribution to journalArticle

  33. MiR-184 regulates pancreatic β-cell function according to glucose metabolism.

    Tattikota, S. G., Rathjen, T., Hausser, J., Khedkar, A., Kabra, U. D., Pandey, V. K., Sury, M., Wessels, H-H., Ines Mollet, Lena Eliasson, Selbach, M., Zinzen, R. P., Zavolan, M., Kadener, S., Tschöp, M., Jastroch, M., Friedländer, M. R. & Poy, M. N., 2015, In : Journal of Biological Chemistry. 290, 33, p. 20284-20294

    Research output: Contribution to journalArticle

  34. 2014
  35. Argonaute2 Mediates Compensatory Expansion of the Pancreatic β Cell.

    Tattikota, S. G., Rathjen, T., McAnulty, S. J., Wessels, H-H., Akerman, I., van de Bunt, M., Hausser, J., Esguerra, J., Musahl, A., Pandey, A. K., You, X., Chen, W., Herrera, P. L., Johnson, P. R., O'Carroll, D., Eliasson, L., Zavolan, M., Gloyn, A. L., Ferrer, J., Shalom-Feuerstein, R. & 2 othersAberdam, D. & Poy, M. N., 2014, In : Cell Metabolism. 19, 1, p. 122-134

    Research output: Contribution to journalArticle

  36. Calcium Current Inactivation Rather than Pool Depletion Explains Reduced Exocytotic Rate with Prolonged Stimulation in Insulin-Secreting INS-1 832/13 Cells.

    Pedersen, M. G., Salunkhe, V. A., Svedin, E., Anna Edlund & Lena Eliasson, 2014, In : PLoS ONE. 9, 8, e103874.

    Research output: Contribution to journalArticle

  37. Dynamic Magnetic Fields Remote-Control Apoptosis via Nanoparticle Rotation.

    Enming Zhang, Kircher, M. F., Koch, M., Lena Eliasson, Goldberg, S. N. & Erik Renström, 2014, In : ACS Nano. 8, 4, p. 3192-3201

    Research output: Contribution to journalArticle

  38. Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism.

    Fadista, J., Vikman, P., Ottosson Laakso, E., Mollet, I., Esguerra, J., Taneera, J., Storm, P., Osmark, P., Ladenvall, C., Prasad, R., Hansson, K. B., Finotello, F., Uvebrant, K., Ofori, J., Di Camillo, B., Krus, U., Cilio, C., Hansson, O., Eliasson, L., Rosengren, A. & 3 othersErik Renström, Claes Wollheim & Leif Groop, 2014, In : Proceedings of the National Academy of Sciences. 111, 38, p. 13924-13929

    Research output: Contribution to journalArticle

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