Lotta Gustafsson

Medical doctor and scientist, M.D, Ph.D, M.Sc, affiliated with the university, Specialist M.D in dermatology and venereology, Medical Doctor M.D, Doctor of Philosophy, Master in Science M.Sc
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  1. alpha-Lactalbumin unfolding is not sufficient to cause apoptosis, but is required for the conversion to HAMLET (human alpha-lactalbumin made lethal to tumor cells).

    Malin Svensson, Jonas Fast, Anki Mossberg, Caroline Düringer, Lotta Gustafsson, Oskar Hallgren, Charles L. Brooks, Lawrence Berliner, Sara Linse & Catharina Svanborg, 2003, In: Protein Science. 12, 12, p. 2794-2804

    Research output: Contribution to journalArticle

  2. Bladder cancers respond to intravesical instillation of HAMLET (human alpha-lactalbumin made lethal to tumor cells).

    Anki Mossberg, Björn Wullt, Lotta Gustafsson, Wiking Månsson, Eva Ljunggren & Catharina Svanborg, 2007, In: International Journal of Cancer. 121, 6, p. 1352-1359

    Research output: Contribution to journalArticle

  3. Bröstmjölk mot cancerceller

    Lotta Gustafsson, 2007, Illustrerad Vetenskap.

    Research output: Contribution to specialist publication or newspaperNewspaper article

  4. Can misfolded proteins be beneficial? The HAMLET case.

    Jenny Pettersson, Sonja Aits, Lotta Gustafsson, Anki Mossberg, Petter Storm, Maria Trulsson, Filip Persson, K Hun Mok & Catharina Svanborg, 2009, In: Annals of Medicine. 41, p. 162-176

    Research output: Contribution to journalReview article

  5. Ceramide as a TLR4 agonist; a putative signalling intermediate between sphingolipid receptors for microbial ligands and TLR4.

    Hans Fischer, Patrik Ellström, Kristina Ekström-Holka, Lotta Gustafsson, Mattias Gustafsson & Catharina Svanborg, 2007, In: Cellular Microbiology. 9, 5, p. 1239-1251

    Research output: Contribution to journalArticle

  6. Endothelin receptor-mediated vasodilatation: Effects of organ culture.

    David Nilsson, Angelica Wackenfors, Lotta Gustafsson, Martin Ugander, Per Paulsson, Richard Ingemansson, Lars Edvinsson & Malin Malmsjö, 2008, In: European Journal of Pharmacology. 579, 1-3, p. 233-240

    Research output: Contribution to journalArticle

  7. Enhancement of anti-tumor effects of checkpoint inhibitors by selenium in melanoma.

    Lotta Gustafsson, 2010 Mar 7.

    Research output: Contribution to conferenceAbstract

  8. HAMLET; a novel tool to identify apoptotic pathways in tumor cells.

    Caroline Düringer, Oskar Hallgren, Lotta Gustafsson, Jenny Pettersson, Anki Mossberg, Taras Manolov & Catharina Svanborg, 2005, Application of apoptosis to cancer treatment.. Mels, S. (ed.). Springer, p. 223-245

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

  9. HAMLET - a protein lipid complex from human milk that kills tumor cells

    Lotta Gustafsson, 2002 Oct 6.

    Research output: Contribution to conferenceAbstract

  10. HAMLET, a tumoricidal molecular complex from human milk

    C Svanborg, S Aits, P Brest, L Gustafsson, K Mok, C Moreillhon, A Mossberg, J Pettersson, P Storm & M Trulsson, 2009 Jul 24, In: BMC Proceedings. 3, Suppl 5, p. S11

    Research output: Contribution to journalPublished meeting abstract

  11. HAMLET (human alpha-lactalbumin made lethal to tumor cells) triggers autophagic tumor cell death.

    Sonja Aits, Lotta Gustafsson, Oskar Hallgren, Patrick Brest, Mattias Gustafsson, Maria Trulsson, Anki Mossberg, Hans-Uwe Simon, Baharia Mograbi & Catharina Svanborg, 2009, In: International Journal of Cancer. 124, 5, p. 1008-1019

    Research output: Contribution to journalArticle

  12. HAMLET induced tumor cell apoptosis - molecular, cellular and therapeutic aspects

    Lotta Gustafsson, 2002 May 31.

    Research output: Contribution to conferenceAbstract

  13. HAMLET interacts with histones and chromatin in tumor cell nuclei.

    Caroline Düringer, Ali Hamiche, Lotta Gustafsson, Hiroshi Kimura & Catharina Svanborg, 2003, In: Journal of Biological Chemistry. 278, 43, p. 42131-42135

    Research output: Contribution to journalArticle

  14. HAMLET - In vivo effects and mechanisms of tumor-cell death

    Lotta Gustafsson, 2005, Department of Laboratory Medicine, Lund University. 95 p.

    Research output: ThesisDoctoral Thesis (compilation)

  15. HAMLET kills tumor cells by an apoptosis-like mechanism--cellular, molecular, and therapeutic aspects.

    Catharina Svanborg, Helena Ågerstam, Annika Aronson, Rolf Bjerkvig, Caroline Düringer, Walter Fischer, Lotta Gustafsson, Oskar Hallgren, Irene Leijonhuvud, Sara Linse, Anki Mossberg, Hanna Nilsson, Jenny Pettersson & Malin Svensson, 2003, In: Advances in Cancer Research. 88, p. 1-29

    Research output: Contribution to journalReview article

  16. HAMLET kills tumor cells by apoptosis: Structure, cellular mechanisms, and therapy

    Lotta Gustafsson, Oskar Hallgren, Anki Mossberg, Jenny Pettersson, W Fischer, Annika Aronsson & Catharina Svanborg, 2005, In: Journal of Nutrition. 135, 5, p. 1299-1303

    Research output: Contribution to journalArticle

  17. HAMLET, protein folding, and tumor cell death

    K. Hun Mok, Jenny Pettersson, Sten Orrenius, Catharina Svanborg & Lotta Gustafsson, 2007, In: Biochemical and Biophysical Research Communications. 354, 1, p. 1-7

    Research output: Contribution to journalReview article

  18. HAMLET triggers apoptosis but tumor cell death is independent of caspases, Bcl-2 and p53.

    Oskar Hallgren, Lotta Gustafsson, Heikki Irjala, G Selivanova, S Orrenius & Catharina Svanborg, 2006, In: Apoptosis. 11, 2, p. 221-233

    Research output: Contribution to journalArticle

  19. Histone deacetylase inhibitors promote the tumoricidal effect of HAMLET.

    Patrick Brest, Mattias Gustafsson, Anki Mossberg, Lotta Gustafsson, Caroline Düringer, Ali Hamiche & Catharina Svanborg, 2007, In: Cancer Research. 67, 23, p. 11327-11334

    Research output: Contribution to journalArticle

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