Lotta Gustafsson

Medical doctor and scientist, M.D, Ph.D, M.Sc, affiliated with the university, Specialist M.D in dermatology and venereology, Medical Doctor M.D, Doctor of Philosophy, Master in Science M.Sc
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  1. 2007
  2. Ceramide as a TLR4 agonist; a putative signalling intermediate between sphingolipid receptors for microbial ligands and TLR4.

    Hans Fischer, Patrik Ellström, Kristina Ekström-Holka, Lotta Gustafsson, Mattias Gustafsson & Catharina Svanborg, 2007, In: Cellular Microbiology. 9, 5, p. 1239-1251

    Research output: Contribution to journalArticle

  3. HAMLET, protein folding, and tumor cell death

    K. Hun Mok, Jenny Pettersson, Sten Orrenius, Catharina Svanborg & Lotta Gustafsson, 2007, In: Biochemical and Biophysical Research Communications. 354, 1, p. 1-7

    Research output: Contribution to journalReview article

  4. Histone deacetylase inhibitors promote the tumoricidal effect of HAMLET.

    Patrick Brest, Mattias Gustafsson, Anki Mossberg, Lotta Gustafsson, Caroline Düringer, Ali Hamiche & Catharina Svanborg, 2007, In: Cancer Research. 67, 23, p. 11327-11334

    Research output: Contribution to journalArticle

  5. 2006
  6. HAMLET triggers apoptosis but tumor cell death is independent of caspases, Bcl-2 and p53.

    Oskar Hallgren, Lotta Gustafsson, Heikki Irjala, G Selivanova, S Orrenius & Catharina Svanborg, 2006, In: Apoptosis. 11, 2, p. 221-233

    Research output: Contribution to journalArticle

  7. Sternal stability at different negative pressures during vacuum-assisted closure therapy

    Arash Mokhtari, Rainer Petzina, Lotta Gustafsson, Johan Sjögren, Malin Malmsjö & Richard Ingemansson, 2006, In: Annals of Thoracic Surgery. 82, 3, p. 1063-1067

    Research output: Contribution to journalArticle

  8. Unfolded Protein Overload, Proteasome Activation and Death in HAMLET-Treated Tumor Cells

    Lotta Gustafsson, Oskar Hallgren, Barbara Spolaore, Carol Robinsson & Catharina Svanborg, 2006, In: IDrugs. 9, 3, p. B29

    Research output: Contribution to journalPublished meeting abstract

  9. 2005
  10. HAMLET; a novel tool to identify apoptotic pathways in tumor cells.

    Caroline Düringer, Oskar Hallgren, Lotta Gustafsson, Jenny Pettersson, Anki Mossberg, Taras Manolov & Catharina Svanborg, 2005, Application of apoptosis to cancer treatment.. Mels, S. (ed.). Springer, p. 223-245

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

  11. HAMLET - In vivo effects and mechanisms of tumor-cell death

    Lotta Gustafsson, 2005, Department of Laboratory Medicine, Lund University. 95 p.

    Research output: ThesisDoctoral Thesis (compilation)

  12. HAMLET kills tumor cells by apoptosis: Structure, cellular mechanisms, and therapy

    Lotta Gustafsson, Oskar Hallgren, Anki Mossberg, Jenny Pettersson, W Fischer, Annika Aronsson & Catharina Svanborg, 2005, In: Journal of Nutrition. 135, 5, p. 1299-1303

    Research output: Contribution to journalArticle

  13. 2004
  14. Human alpha-lactalbumin made lethal to tumor cells (HAMLET) kills human glioblastoma cells in brain xenografts by an apoptosis-like mechanism and prolongs survival.

    Walter Fischer, Lotta Gustafsson, Anki Mossberg, Janne Gronli, Sverre Mork, Rolf Bjerkvig & Catharina Svanborg, 2004, In: Cancer Research. 64, 6, p. 2105-2112 8 p.

    Research output: Contribution to journalArticle

  15. Treatment of skin papillomas with topical alpha-lactalbumin-oleic acid

    Lotta Gustafsson, Irene Leijonhufvud, Annika Aronsson, Anki Mossberg & Catharina Svanborg, 2004, In: New England Journal of Medicine. 350, 26, p. 2663-2672

    Research output: Contribution to journalArticle

  16. 2003
  17. alpha-Lactalbumin unfolding is not sufficient to cause apoptosis, but is required for the conversion to HAMLET (human alpha-lactalbumin made lethal to tumor cells).

    Malin Svensson, Jonas Fast, Anki Mossberg, Caroline Düringer, Lotta Gustafsson, Oskar Hallgren, Charles L. Brooks, Lawrence Berliner, Sara Linse & Catharina Svanborg, 2003, In: Protein Science. 12, 12, p. 2794-2804

    Research output: Contribution to journalArticle

  18. HAMLET interacts with histones and chromatin in tumor cell nuclei.

    Caroline Düringer, Ali Hamiche, Lotta Gustafsson, Hiroshi Kimura & Catharina Svanborg, 2003, In: Journal of Biological Chemistry. 278, 43, p. 42131-42135

    Research output: Contribution to journalArticle

  19. HAMLET kills tumor cells by an apoptosis-like mechanism--cellular, molecular, and therapeutic aspects.

    Catharina Svanborg, Helena Ågerstam, Annika Aronson, Rolf Bjerkvig, Caroline Düringer, Walter Fischer, Lotta Gustafsson, Oskar Hallgren, Irene Leijonhuvud, Sara Linse, Anki Mossberg, Hanna Nilsson, Jenny Pettersson & Malin Svensson, 2003, In: Advances in Cancer Research. 88, p. 1-29

    Research output: Contribution to journalReview article

  20. 2002
  21. HAMLET - a protein lipid complex from human milk that kills tumor cells

    Lotta Gustafsson, 2002 Oct 6.

    Research output: Contribution to conferenceAbstract

  22. HAMLET induced tumor cell apoptosis - molecular, cellular and therapeutic aspects

    Lotta Gustafsson, 2002 May 31.

    Research output: Contribution to conferenceAbstract

  23. Uptake and intracellular transportation of a bacterial surface protein in lymphoid cells.

    Inga-Maria Frick, Karol Axcrona, Ylva Härdig, Hans Tapper, Lotta Gustafsson, Roland Kellner, Tomas Leanderson & Lars Björck, 2002, In: Molecular Microbiology. 44, 4, p. 917-934

    Research output: Contribution to journalArticle

  24. 2001
  25. Protective effects of breast milk

    Lotta Gustafsson, 2001 Oct.

    Research output: Contribution to conferenceAbstract

  26. Photodynamic therapy and diagnostic measurements of basal cell carcinomas using esterified and non-esterified delta-aminolevulinic acid

    Marcelo Soto Thompson, Lotta Gustafsson, Sara Pålsson, Niels Bendsöe, Maria Stenberg, Claes af Klinteberg, Stefan Andersson-Engels & Katarina Svanberg, 2001, In: Journal of Porphyrins and Phthalocyanines. 5, 2, p. 147

    Research output: Contribution to journalArticle

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