Malin Wennström

Researcher, Associate professor, PhD, Master of science

Research areas and keywords

UKÄ subject classification

  • Medical and Health Sciences
  • Neurosciences

Keywords

  • Alzheimers disease, pericytes, neuroinflammation, a stress, amyloid peptides, amyloid beta, amylin, glycogen, Amylase

Research

Our goal is to identify new early mechanisms and biomarkers associated with Alzheimer’s disease (AD), and thereby improve development of new treatments and diagnostic tools. To do so we have over the years, together with national and international colleagues and collaborators, investigated the impact of AD risk factors (such as stress, inflammation, metabolic changes and amyloidogenesis) on different types of brain cells. Our scientific approach is to use translational studies primarily conducted on human samples (brain, retina, CSF and cells isolated from postmortem adult and fetal brain). By the use of such studies, we have revealed several new mechanisms and biomarkers associated with AD, including alteration of glycogen metabolism, toxicity/specificity of varios amyloid peptides and secretion of various pathology-specific molecules.  

Recent research outputs

Boza-Serrano, A., Ruiz, R., Sanchez-Varo, R., García-Revilla, J., Yang, Y., Jimenez-Ferrer, I., Paulus, A., Wennström, M., Vilalta, A., Allendorf, D., Davila, J. C., Stegmayr, J., Jiménez, S., Roca-Ceballos, M. A., Navarro-Garrido, V., Swanberg, M., Hsieh, C. L., Real, L. M., Englund, E., Linse, S. & 7 othersHakon Leffler, Ulf J. Nilsson, Brown, G. C., Gutierrez, A., Vitorica, J., Venero, J. L. & Tomas Deierborg, 2019, In : Acta Neuropathologica. 138, 2, p. 251-273

Research output: Contribution to journalArticle

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