Markus Ringnér

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  1. 2019
  2. Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation

    Brinkman, A. B., Nik-Zainal, S., Simmer, F., Rodríguez-González, F. G., Smid, M., Alexandrov, L. B., Butler, A., Martin, S., Davies, H., Glodzik, D., Zou, X., Ramakrishna, M., Staaf, J., Ringnér, M., Sieuwerts, A., Ferrari, A., Morganella, S., Fleischer, T., Kristensen, V., Gut, M. & 9 othersvan de Vijver, M. J., Børresen-Dale, A. L., Richardson, A. L., Thomas, G., Gut, I. G., Martens, J. W. M., Foekens, J. A., Stratton, M. R. & Stunnenberg, H. G., 2019 Apr 15, In : Nature Communications. 10, 1, 1749.

    Research output: Contribution to journalArticle

  3. 2018
  4. A comprehensive map coupling histone modifications with gene regulation in adult dopaminergic and serotonergic neurons

    Södersten, E., Toskas, K., Rraklli, V., Tiklova, K., Björklund, Å. K., Markus Ringnér, Perlmann, T. & Holmberg, J., 2018 Mar 26, In : Nature Communications. 9, 1, 1226.

    Research output: Contribution to journalArticle

  5. 2017
  6. 2016
  7. Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration

    Smid, M., Rodríguez-González, F. G., Sieuwerts, A. M., Salgado, R., Prager-Van der Smissen, W. J. C., Vlugt-Daane, M. V. D., van Galen, A., Nik-Zainal, S., Staaf, J., Brinkman, A. B., van de Vijver, M. J., Richardson, A. L., Fatima, A., Berentsen, K., Butler, A., Martin, S., Davies, H. R., Debets, R., Gelder, M. E. M-V., van Deurzen, C. H. M. & 27 othersMacGrogan, G., Van den Eynden, G. G. G. M., Purdie, C., Thompson, A. M., Caldas, C., Span, P. N., Simpson, P. T., Lakhani, S. R., Van Laere, S., Desmedt, C., Markus Ringnér, Tommasi, S., Eyford, J., Broeks, A., Vincent-Salomon, A., Futreal, P. A., Knappskog, S., King, T., Thomas, G., Viari, A., Langerød, A., Børresen-Dale, A-L., Birney, E., Stunnenberg, H. G., Stratton, M., Foekens, J. A. & Martens, J. W. M., 2016 Sep 27, In : Nature Communications. 7, 12910.

    Research output: Contribution to journalArticle

  8. Consensus of gene expression phenotypes and prognostic risk predictors in primary lung adenocarcinoma

    Markus Ringnér & Johan Staaf, 2016 Jul 16, In : Oncotarget. 7, 33, p. 52957-52973 17 p.

    Research output: Contribution to journalArticle

  9. Landscape of somatic mutations in 560 breast cancer whole-genome sequences

    Nik-Zainal, S., Davies, H., Staaf, J., Ramakrishna, M., Glodzik, D., Zou, X., Martincorena, I., Alexandrov, L. B., Martin, S., Wedge, D. C., Van Loo, P., Ju, Y. S., Smid, M., Brinkman, A. B., Morganella, S., Aure, M. R., Lingjærde, O. C., Langerød, A., Ringnér, M., Ahn, S-M. & 68 othersBoyault, S., Brock, J. E., Broeks, A., Butler, A., Desmedt, C., Dirix, L., Dronov, S., Fatima, A., Foekens, J. A., Gerstung, M., Hooijer, G. K. J., Jang, S. J., Jones, D. R., Kim, H-Y., King, T. A., Krishnamurthy, S., Lee, H. J., Lee, J-Y., Li, Y., McLaren, S., Menzies, A., Mustonen, V., O'Meara, S., Pauporté, I., Pivot, X., Purdie, C. A., Raine, K., Ramakrishnan, K., Rodríguez-González, F. G., Romieu, G., Sieuwerts, A. M., Simpson, P. T., Shepherd, R., Stebbings, L., Stefansson, O. A., Teague, J., Tommasi, S., Treilleux, I., Van den Eynden, G. G., Vermeulen, P., Vincent-Salomon, A., Yates, L., Caldas, C., van't Veer, L., Tutt, A., Knappskog, S., Tan, B. K. T., Jonkers, J., Åke Borg, Ueno, N. T., Sotiriou, C., Viari, A., Futreal, P. A., Campbell, P. J., Span, P. N., Van Laere, S., Lakhani, S. R., Eyfjord, J. E., Thompson, A. M., Birney, E., Stunnenberg, H. G., van de Vijver, M. J., Martens, J. W. M., Børresen-Dale, A-L., Richardson, A. L., Kong, G., Thomas, G. & Stratton, M. R., 2016 Jun 2, In : Nature. 534, 7605, p. 47-54 8 p.

    Research output: Contribution to journalArticle

  10. 2015
  11. DNA methylation and histone modifications regulate SOX11 expression in lymphoid and solid cancer cells.

    Nordström, L., Andersson, E., Kuci, V., Gustavsson, E., Karolina Holm, Markus Ringnér, Guldberg, P. & Ek, S., 2015, In : BMC Cancer. 15, 1, 273.

    Research output: Contribution to journalArticle

  12. Making breast cancer molecular subtypes robust?

    Johan Staaf & Markus Ringnér, 2015, In : Journal of the National Cancer Institute. 107, 1, p. dju386

    Research output: Contribution to journalDebate/Note/Editorial

  13. MicroRNA-200c-141 and ∆Np63 are required for breast epithelial differentiation and branching morphogenesis.

    Hilmarsdóttir, B., Briem, E., Valgardur Sigurdsson, Franzdóttir, S. R., Markus Ringnér, Arason, A. J., Bergthorsson, J. T., Magnusson, M. K. & Gudjonsson, T., 2015, In : Developmental Biology. 403, 2, p. 150-161

    Research output: Contribution to journalArticle

  14. 2014
  15. Genomic and transcriptional alterations in lung adenocarcinoma in relation to smoking history.

    Karlsson, A. K., Markus Ringnér, Martin Lauss, Botling, J., Micke, P., Maria Planck & Johan Staaf, 2014, In : Clinical Cancer Research. 20, 18, p. 4912-4924

    Research output: Contribution to journalArticle

  16. Primary Melanoma Tumors from CDKN2A Mutation Carriers do not Belong to a Distinct Molecular Subclass.

    Johan Staaf, Katja Harbst, Martin Lauss, Markus Ringnér, Måsbäck, A., Jillian Howlin, Karin Jirström, Harland, M., Zebary, A., Palmer, J. M., Christian Ingvar, Håkan Olsson, Newton-Bishop, J., Hansson, J., Hayward, N., Gruis, N. & Göran B Jönsson, 2014, In : Journal of Investigative Dermatology. 134, 12, p. 3000-3003

    Research output: Contribution to journalArticle

  17. 2013
  18. Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development.

    Kucharzewska, P., Christianson, H., Welch, J., Svensson, K., Fredlund, E., Markus Ringnér, Mörgelin, M., Bourseau-Guilmain, E., Johan Bengzon & Mattias Belting, 2013, In : Proceedings of the National Academy of Sciences. 110, 18, p. 7312-7317

    Research output: Contribution to journalArticle

  19. High expression of ZNF703 independent of amplification indicates worse prognosis in patients with luminal B breast cancer

    Reynisdottir, I., Arason, A., Einarsdottir, B., Gunnarsson, H., Johan Staaf, Johan Vallon-Christersson, Göran B Jönsson, Markus Ringnér, Agnarsson, B., Olafsdottir, K., Fagerholm, R., Einarsdottir, T., Johannesdottir, G., Johannsson, O. T., Nevanlinna, H., Åke Borg & Barkardottir, R., 2013, In : Cancer Medicine. 2, 4, p. 437-446

    Research output: Contribution to journalArticle

  20. Monitoring of technical variation in quantitative high-throughput datasets.

    Martin Lauss, Visne, I., Kriegner, A., Markus Ringnér, Göran B Jönsson & Mattias Höglund, 2013, In : Cancer Informatics. 12, Sep 23, p. 193-201

    Research output: Contribution to journalArticle

  21. Nonfamilial breast cancer subtypes.

    Markus Ringnér, Johan Staaf & Göran B Jönsson, 2013, In : Methods in Molecular Biology. 973, p. 279-295

    Research output: Contribution to journalArticle

  22. The Landscape of Candidate Driver Genes Differs between Male and Female Breast Cancer.

    Johansson, I., Markus Ringnér & Ingrid Hedenfalk, 2013, In : PLoS ONE. 8, 10, e78299.

    Research output: Contribution to journalArticle

  23. 2012
  24. A Molecular Taxonomy for Urothelial Carcinoma.

    Gottfrid Sjödahl, Martin Lauss, Lövgren, K., Chebil, G., Gudjonsson, S., Veerla, S., Oliver Hultman Patschan, Mattias Aine, Mårten Fernö, Markus Ringnér, Wiking Månsson, Fredrik Liedberg, David Lindgren & Mattias Höglund, 2012, In : Clinical Cancer Research. 18, 12, p. 3377-3386

    Research output: Contribution to journalArticle

  25. Gene expression profiling of primary male breast cancers reveals two unique subgroups and identifies N-acetyltransferase-1 (NAT1) as a novel prognostic biomarker

    Johansson, I., Nilsson, C., Berglund, P., Martin Lauss, Markus Ringnér, Håkan Olsson, Luts, L., Sim, E., Thorstensson, S., Fjallskog, M-L. & Ingrid Hedenfalk, 2012, In : Breast Cancer Research. 14, 1, R31.

    Research output: Contribution to journalArticle

  26. Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes.

    Karolina Holm, Grabau, D., Lövgren, K., Aradottir, S., Sofia Gruvberger, Jillian Howlin, Lao Saal, Ethier, S. P., Pär-Ola Bendahl, Stål, O., Per Malmström, Mårten Fernö, Lisa Rydén, Cecilia Hegardt, Åke Borg & Markus Ringnér, 2012, In : Molecular Oncology. 6, 5, p. 494-506

    Research output: Contribution to journalArticle

  27. The gene expression landscape of breast cancer is shaped by tumor protein p53 status and epithelial-mesenchymal transition

    Fredlund, E., Johan Staaf, Rantala, J. K., Kallioniemi, O., Åke Borg & Markus Ringnér, 2012, In : Breast Cancer Research. 14, 4, R113.

    Research output: Contribution to journalArticle

  28. The retinoblastoma gene undergoes rearrangements in BRCA1-deficient basal-like breast cancer.

    Jönsson, G. B., Staaf, J., Vallon-Christersson, J., Ringnér, M., Gruvberger, S., Saal, L., Holm, K., Hegardt, C., Arason, A., Fagerholm, R., Olsson, C., Grabau, D., Johnsson, E., Lövgren, K., Magnusson, L., Heikkilä, P., Agnarsson, B. A., Johannsson, O. T., Malmström, P., Fernö, M. & 5 othersHåkan Olsson, Niklas Loman, Nevanlinna, H., Barkardottir, R. B. & Åke Borg, 2012, In : Cancer Research. 72, 16, p. 4028-4036

    Research output: Contribution to journalArticle

  29. 2011
  30. Endothelial Induced EMT in Breast Epithelial Cells with Stem Cell Properties

    Sigurdsson, V., Hilmarsdottir, B., Sigmundsdottir, H., Fridriksdottir, A. J. R., Markus Ringnér, Villadsen, R., Åke Borg, Agnarsson, B. A., Petersen, O. W., Magnusson, M. K. & Gudjonsson, T., 2011, In : PLoS ONE. 6, 9, e23833.

    Research output: Contribution to journalArticle

  31. GOBO: Gene Expression-Based Outcome for Breast Cancer Online.

    Markus Ringnér, Fredlund, E., Jari Häkkinen, Åke Borg & Johan Staaf, 2011, In : PLoS ONE. 6, 3, e17911.

    Research output: Contribution to journalArticle

  32. High-resolution genomic profiling of male breast cancer reveals differences hidden behind the similarities with female breast cancer

    Johansson, I., Nilsson, C., Berglund, P., Carina Forsare, Göran B Jönsson, Johan Staaf, Markus Ringnér, Nevanlinna, H., Barkardottir, R. B., Åke Borg, Håkan Olsson, Luts, L., Fjallskog, M-L. & Ingrid Hedenfalk, 2011, In : Breast Cancer Research and Treatment. 129, 3, p. 747-760

    Research output: Contribution to journalArticle

  33. 2010
  34. An integrative genomics screen uncovers ncRNA T-UCR functions in neuroblastoma tumours

    Mestdagh, P., Fredlund, E., Pattyn, F., Rihani, A., Van Maerken, T., Vermeulen, J., Kumps, C., Menten, B., De Preter, K., Schramm, A., Schulte, J., Noguera, R., Schleiermacher, G., Janoueix-Lerosey, I., Laureys, G., Powel, R., Nittner, D., Marine, J-C., Ringnér, M., Speleman, F. & 1 othersVandesompele, J., 2010, In : Oncogene. 29, 24, p. 3583-3592

    Research output: Contribution to journalArticle

  35. Gene Expression Profiling-Based Identification of Molecular Subtypes in Stage IV Melanomas with Different Clinical Outcome.

    Göran B Jönsson, Busch, C., Knappskog, S., Geisler, J., Miletic, H., Markus Ringnér, Lillehaug, J. R., Åke Borg & Lonning, P. E., 2010, In : Clinical Cancer Research. 16, 13, p. 3356-3367

    Research output: Contribution to journalArticle

  36. Genomic subtypes of breast cancer identified by array-comparative genomic hybridization display distinct molecular and clinical characteristics

    Jönsson, G. B., Staaf, J., Vallon-Christersson, J., Ringnér, M., Holm, K., Hegardt, C., Gunnarsson, H., Fagerholm, R., Forsare, C., Agnarsson, B. A., Kilpivaara, O., Luts, L., Heikkila, P., Aittomaki, K., Blomqvist, C., Loman, N., Malmström, P., Olsson, H., Johannsson, O. T., Arason, A. & 3 othersNevanlinna, H., Barkardottir, R. B. & Åke Borg, 2010, In : Breast Cancer Research. 12, 3, R42.

    Research output: Contribution to journalArticle

  37. High-resolution genomic and expression analyses of copy number alterations in HER2-amplified breast cancer

    Johan Staaf, Göran B Jönsson, Markus Ringnér, Johan Vallon-Christersson, Grabau, D., Arason, A., Gunnarsson, H., Agnarsson, B. A., Per Malmström, Johannsson, O. T., Niklas Loman, Barkardottir, R. B. & Åke Borg, 2010, In : Breast Cancer Research. 12, 3, R25.

    Research output: Contribution to journalArticle

  38. 2008
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