Nikolay Oskolkov

Bioinformatician
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  1. 2018
  2. 2017
  3. Glucose-induced Changes in Gene Expression in Human Pancreatic Islets - Causes or Consequences of Chronic Hyperglycemia

    Ottosson-Laakso, E., Krus, U., Storm, P., Rashmi B Prasad, Nikolay Oskolkov, Emma Ahlqvist, Fadista, J., Ola Hansson, Leif Groop & Petter Vikman, 2017, In : Diabetes. 66, 12, p. 3013-3028

    Research output: Contribution to journalArticle

  4. LoFtool: a gene intolerance score based on loss-of-function variants in 60 706 individuals

    Fadista, J., Nikolay Oskolkov, Ola Hansson & Leif Groop, 2017, In : Bioinformatics. 33, 4, p. 471-474

    Research output: Contribution to journalArticle

  5. 2016
  6. Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes

    Dooley, J., Tian, L., Schonefeldt, S., Delghingaro-Augusto, V., Garcia-Perez, J. E., Pasciuto, E., Di Marino, D., Carr, E. J., Oskolkov, N., Lyssenko, V., Franckaert, D., Lagou, V., Overbergh, L., Vandenbussche, J., Allemeersch, J., Chabot-Roy, G., Dahlstrom, J. E., Laybutt, D. R., Petrovsky, N., Socha, L. & 9 othersGevaert, K., Jetten, A. M., Lambrechts, D., Linterman, M. A., Goodnow, C. C., Nolan, C. J., Lesage, S., Schlenner, S. M. & Liston, A., 2016, In : Nature Genetics. 48, p. 519-527

    Research output: Contribution to journalArticle

  7. HMGB1 binds to the rs7903146 locus in TCF7L2 in human pancreatic islets.

    Zhou, Y., Nikolay Oskolkov, Liliya Shcherbina, Ratti, J., Kock, K-H., Su, J., Martin, B., Zackrisson Oskolkova, M., Olga Göransson, Bacon, J., Li, W., Bucciarelli, S., Corrado Cilio, Brazma, A., Thatcher, B., Rung, J., Nils Wierup, Erik Renström, Leif Groop & Ola Hansson, 2016, In : Molecular and Cellular Endocrinology. 430, p. 138-145 8 p.

    Research output: Contribution to journalArticle

  8. 2015
  9. A novel atlas of gene expression in human skeletal muscle reveals molecular changes associated with aging.

    Su, J., Carl Ekman, Nikolay Oskolkov, Lahti, L., Ström, K., Brazma, A., Leif Groop, Rung, J. & Ola Hansson, 2015, In : Skeletal Muscle. 5, 35.

    Research output: Contribution to journalArticle

  10. Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.

    Gaulton, K. J., Ferreira, T., Lee, Y., Raimondo, A., Mägi, R., Reschen, M. E., Mahajan, A., Locke, A., William Rayner, N., Robertson, N., Scott, R. A., Prokopenko, I., Scott, L. J., Green, T., Sparso, T., Thuillier, D., Yengo, L., Grallert, H., Wahl, S., Frånberg, M. & 198 othersStrawbridge, R. J., Kestler, H., Chheda, H., Eisele, L., Gustafsson, S., Steinthorsdottir, V., Thorleifsson, G., Qi, L., Karssen, L. C., van Leeuwen, E. M., Willems, S. M., Li, M., Chen, H., Fuchsberger, C., Kwan, P., Ma, C., Linderman, M., Lu, Y., Thomsen, S. K., Rundle, J. K., Beer, N. L., van de Bunt, M., Chalisey, A., Kang, H. M., Voight, B. F., Abecasis, G. R., Almgren, P., Baldassarre, D., Balkau, B., Benediktsson, R., Blüher, M., Boeing, H., Bonnycastle, L. L., Bottinger, E. P., Burtt, N. P., Carey, J., Charpentier, G., Chines, P. S., Cornelis, M. C., Couper, D. J., Crenshaw, A. T., van Dam, R. M., Doney, A. S. F., Mozhgan Dorkhan, Edkins, S., Eriksson, J. G., Esko, T., Eury, E., Fadista, J., Flannick, J., Fontanillas, P., Fox, C., Paul Franks, Gertow, K., Gieger, C., Gigante, B., Gottesman, O., Grant, G. B., Grarup, N., Groves, C. J., Hassinen, M., Have, C. T., Herder, C., Holmen, O. L., Hreidarsson, A. B., Humphries, S. E., Hunter, D. J., Jackson, A. U., Jonsson, A., Jørgensen, M. E., Jørgensen, T., Kao, W-H. L., Kerrison, N. D., Kinnunen, L., Klopp, N., Kong, A., Kovacs, P., Kraft, P., Jasmina Kravic, Langford, C., Leander, K., Liang, L., Lichtner, P., Lindgren, C. M., Eero Lindholm, Linneberg, A., Liu, C-T., Lobbens, S., Luan, J., Valeriya Lyssenko, Männistö, S., McLeod, O., Meyer, J., Mihailov, E., Mirza, G., Mühleisen, T. W., Müller-Nurasyid, M., Navarro, C., Nöthen, M. M., Nikolay Oskolkov, Owen, K. R., Palli, D., Pechlivanis, S., Peltonen, L., Perry, J. R. B., Platou, C. G. P., Roden, M., Ruderfer, D., Rybin, D., van der Schouw, Y. T., Sennblad, B., Sigurðsson, G., Stančáková, A., Steinbach, G., Storm, P., Strauch, K., Stringham, H. M., Sun, Q., Thorand, B., Tikkanen, E., Tonjes, A., Trakalo, J., Tremoli, E., Tuomi, T., Wennauer, R., Wiltshire, S., Wood, A. R., Zeggini, E., Dunham, I., Birney, E., Pasquali, L., Ferrer, J., Loos, R. J. F., Dupuis, J., Florez, J. C., Boerwinkle, E., Pankow, J. S., van Duijn, C., Sijbrands, E., Meigs, J. B., Hu, F. B., Thorsteinsdottir, U., Stefansson, K., Lakka, T. A., Rauramaa, R., Stumvoll, M., Pedersen, N. L., Lind, L., Keinanen-Kiukaanniemi, S. M., Korpi-Hyövälti, E., Saaristo, T. E., Saltevo, J., Kuusisto, J., Laakso, M., Metspalu, A., Erbel, R., Jöcke, K-H., Moebus, S., Ripatti, S., Salomaa, V., Ingelsson, E., Boehm, B. O., Bergman, R. N., Collins, F. S., Mohlke, K. L., Koistinen, H., Tuomilehto, J., Hveem, K., Njølstad, I., Deloukas, P., Donnelly, P. J., Frayling, T. M., Hattersley, A. T., de Faire, U., Hamsten, A., Illig, T., Peters, A., Cauchi, S., Sladek, R., Froguel, P., Hansen, T., Pedersen, O., Morris, A. D., Palmer, C. N. A., Kathiresan, S., Olle Melander, Peter Nilsson, Leif Groop, Barroso, I., Langenberg, C., Wareham, N. J., O'Callaghan, C. A., Gloyn, A. L., Altshuler, D., Boehnke, M., Teslovich, T. M., McCarthy, M. I. & Morris, A. P., 2015, In : Nature Genetics. 47, 12, p. 1415

    Research output: Contribution to journalArticle

  11. Myocardin Family Members Drive Formation of Caveolae.

    Katarzyna Krawczyk, Ingrid Yao Mattisson, Ekman, M., Nikolay Oskolkov, Grantinge, R., Kotowska, D., Björn Olde, Ola Hansson, Sebastian Albinsson, Miano, J. M., Catarina Rippe & Karl Swärd, 2015, In : PLoS ONE. 10, 8, e0133931.

    Research output: Contribution to journalArticle

  12. 2014
  13. Leveraging cross-species transcription factor binding site patterns: from diabetes risk Loci to disease mechanisms.

    Claussnitzer, M., Dankel, S. N., Klocke, B., Grallert, H., Glunk, V., Berulava, T., Lee, H., Oskolkov, N., Fadista, J., Ehlers, K., Wahl, S., Hoffmann, C., Qian, K., Rönn, T., Riess, H., Müller-Nurasyid, M., Bretschneider, N., Schroeder, T., Skurk, T., Horsthemke, B. & 17 othersSpieler, D., Klingenspor, M., Seifert, M., Kern, M. J., Mejhert, N., Dahlman, I., Ola Hansson, Hauck, S. M., Blüher, M., Arner, P., Leif Groop, Illig, T., Suhre, K., Hsu, Y-H., Mellgren, G., Hauner, H. & Laumen, H., 2014, In : Cell. 156, 1-2, p. 343-358

    Research output: Contribution to journalArticle

  14. RNA sequencing: current and prospective uses in metabolic research.

    Petter Vikman, Fadista, J. & Nikolay Oskolkov, 2014, In : Journal of Molecular Endocrinology. 53, 2, p. R93-R101

    Research output: Contribution to journalReview article

  15. TCF7L2 is a master regulator of insulin production and processing.

    Zhou, Y., Park, S-Y., Su, J., Bailey, K., Ottosson Laakso, E., Liliya Shcherbina, Nikolay Oskolkov, Enming Zhang, Thevenin, T., Fadista, J., Bennet, H., Petter Vikman, Nils Wierup, Malin Fex, Rung, J., Claes Wollheim, Nobrega, M., Erik Renström, Leif Groop & Ola Hansson, 2014, In : Human Molecular Genetics. 23, 24, p. 6419-6431

    Research output: Contribution to journalArticle