1) Register based prostate cancer research: The Prostate Cancer data Base Sweden (PCBaSe) is probably the most comprehensive and accurate prostate cancer database in the world. It is created through record linkages between the National Prostate Cancer Register (NPCR) of Sweden and several other nationwide, population based, healthcare and demographic registers. NPCR captures 98% of the prostate cancer cases in the Swedish Cancer Registry, to which registration is mandated by law. PCBaSe now includes 180,000 prostate cancer cases and 800,000 control subjects. I have been a member of the PCBaSe steering committee since its creation in 2009. The Principal Investigator of PCBaSe is Professor Pär Stattin, Uppsala University. In March 2016 there were 81 published papers based on research using PCBaSe with a mean impact factor of 7.8; they had been cited 1,400 times in other publications.
2) Clinical prostate cancer research: I am involved in several projects mainly on diagnostics and treatment of non-metastatic prostate cancer. The largest project is a randomised multicentre study of active surveillance for low risk prostate cancer (SAMS), for which I am the Principal Investigator. SAMS had in March 2016 included 600 patients and will stop recruiting at the end of 2016. The first results for secondary endpoints will be analysed in 2017, but there will be another 5 years of follow-up before it is time to analyse the primary endpoint.