Peter Zygmunt

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  1. 2018
  2. The antipyretic effect of paracetamol occurs independent of transient receptor potential ankyrin 1–mediated hypothermia and is associated with prostaglandin inhibition in the brain

    Mirrasekhian, E., Johan L.A. Nilsson, Shionoya, K., Anders Blomgren, Peter M. Zygmunt, Engblom, D., Högestätt, E. D. & Blomqvist, A., 2018, In : FASEB Journal. 32, 10, p. 5751-5759 9 p.

    Research output: Contribution to journalArticle

  3. 2017
  4. TRPA1-FGFR2 binding event is a regulatory oncogenic driver modulated by miRNA-142-3p

    Berrout, J., Kyriakopoulou, E., Moparthi, L., Hogea, A. S., Berrout, L., Ivan, C-E., Lorger, M., Boyle, J. F., Peers, C., Muench, S., Gomez, J. E., Hu, X., Hurst, C., Hall, T., Umamaheswaran, S., Wesley, L., Gagea, M., Shires, M., Manfield, I., Knowles, M. A. & 10 othersDavies, S., Suhling, K., Gonzalez, Y. T., Carragher, N., Macleod, K. G., Abbott, N. J., Calin, G. A., Gamper, N., Peter M. Zygmunt & Timsah, Z., 2017 Dec 1, In : Nature Communications. 8, 1, 983.

    Research output: Contribution to journalArticle

  5. 2016
  6. The N-terminal Ankyrin Repeat domain is not required for electrophile and heat activation of the purified mosquito TRPA1 receptor

    Survery, S., Moparthi, L., Per Kjellbom, Högestätt, E. D., Peter M. Zygmunt & Urban Johanson, 2016 Dec 23, In : Journal of Biological Chemistry. 291, 52, p. 26899-26912 14 p.

    Research output: Contribution to journalArticle

  7. Photosensitization in porphyrias and photodynamic therapy involves TRPA1 and TRPV1

    Babes, A., Sauer, S. K., Moparthi, L., Kichko, T. I., Neacsu, C., Namer, B., Filipovic, M., Peter M. Zygmunt, Reeh, P. W. & Fischer, M. J. M., 2016 May 11, In : Journal of Neuroscience. 36, 19, p. 5264-5278 15 p.

    Research output: Contribution to journalArticle

  8. Human TRPA1 is a heat sensor displaying intrinsic U-shaped thermosensitivity

    Moparthi, L., Kichko, T. I., Eberhardt, M., Högestätt, E. D., Per Kjellbom, Urban Johanson, Reeh, P. W., Leffler, A., Filipovic, M. R. & Peter M Zygmunt, 2016, In : Scientific Reports. 6, 28763.

    Research output: Contribution to journalArticle

  9. 2014
  10. H2S and NO cooperatively regulate vascular tone by activating a neuroendocrine HNO-TRPA1-CGRP signalling pathway.

    Eberhardt, M., Dux, M., Namer, B., Miljkovic, J., Cordasic, N., Will, C., Kichko, T. I., de la Roche, J., Fischer, M., Suárez, S. A., Bikiel, D., Dorsch, K., Leffler, A., Babes, A., Lampert, A., Lennerz, J. K., Jacobi, J., Martí, M. A., Doctorovich, F., Högestätt, E. & 5 othersPeter Zygmunt, Ivanovic-Burmazovic, I., Messlinger, K., Reeh, P. & Filipovic, M. R., 2014, In : Nature Communications. 5, Jul 15, 4381.

    Research output: Contribution to journalArticle

  11. Human TRPA1 is intrinsically cold- and chemosensitive with and without its N-terminal ankyrin repeat domain.

    Moparthi, L., Survery, S., Kreir, M., Simonsen, C., Per Kjellbom, Högestätt, E., Urban Johanson & Peter Zygmunt, 2014, In : Proceedings of the National Academy of Sciences. 111, 47, p. 16901-16906

    Research output: Contribution to journalArticle

  12. TRPA1

    Peter Zygmunt & Högestätt, E., 2014, Mammalian Transient Receptor Potential (TRP) Cation Channels: Handbook of Experimental Pharmacology. Nilius, B. & Flockerzi, V. (eds.). Vol. I. p. 583-630

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

  13. TRPV4-mediated calcium influx and ciliary activity in human native airway epithelial cells.

    Lisa Alenmyr, Lena Uller, Greiff, L., Högestätt, E. & Peter Zygmunt, 2014, In : Basic & Clinical Pharmacology & Toxicology. 114, 2, p. 210-216

    Research output: Contribution to journalArticle

  14. 2013
  15. Fatty Acid Amide Hydrolase-Dependent Generation of Antinociceptive Drug Metabolites Acting on TRPV1 in the Brain

    Barriere, D. A., Mallet, C., Anders Blomgren, Simonsen, C., Daulhac, L., Libert, F., Chapuy, E., Etienne, M., Högestätt, E., Peter Zygmunt & Eschalier, A., 2013, In : PLoS ONE. 8, 8, e70690.

    Research output: Contribution to journalArticle

  16. Monoacylglycerols Activate TRPV1 - A Link between Phospholipase C and TRPV1.

    Peter Zygmunt, Ermund, A., Pouya Movahed Rad, Andersson, D. A., Simonsen, C., Jönsson, B. A., Anders Blomgren, Birnir, B., Bevan, S., Eschalier, A., Mallet, C., Gomis, A. & Högestätt, E., 2013, In : PLoS ONE. 8, 12, e81618.

    Research output: Contribution to journalArticle

  17. 2012
  18. Effect of Mucosal TRPV1 Inhibition in Allergic Rhinitis.

    Lisa Alenmyr, Greiff, L., Morgan Andersson, Sterner, O., Peter Zygmunt & Högestätt, E., 2012, In : Basic & Clinical Pharmacology & Toxicology. 110, p. 264-268

    Research output: Contribution to journalArticle

  19. TRPA1 Contributes to the Acute Inflammatory Response and Mediates Carrageenan-Induced Paw Edema in the Mouse

    Moilanen, L. J., Laavola, M., Kukkonen, M., Korhonen, R., Leppanen, T., Högestätt, E., Peter Zygmunt, Nieminen, R. M. & Moilanen, E., 2012, In : Scientific Reports. 2, 380.

    Research output: Contribution to journalArticle

  20. 2011
  21. Channels: A TR(i)P in the air.

    Peter Zygmunt, 2011, In : Nature Chemical Biology. 7, 10, p. 661-663

    Research output: Contribution to journalArticle

  22. TRPA1 mediates spinal antinociception induced by acetaminophen and the cannabinoid Delta(9)-tetrahydrocannabiorcol

    Andersson, D. A., Gentry, C., Lisa Alenmyr, Killander, D., Lewis, S. E., Andersson, A. S., Bucher, B., Galzi, J-L., Olov Sterner, Bevan, S., Högestätt, E. & Peter Zygmunt, 2011, In : Nature Communications. 2, 551.

    Research output: Contribution to journalArticle

  23. TRPV1 and TRPA1 stimulation induces MUC5B secretion in the human nasal airway in vivo.

    Lisa Alenmyr, Herrmann, A., Högestätt, E., Greiff, L. & Peter Zygmunt, 2011, In : Clinical Physiology and Functional Imaging. 31, 6, p. 435-444

    Research output: Contribution to journalArticle

  24. 2010
  25. In vitro TRPV1 activity of piperine derived amides

    Andres Correa, E., Högestätt, E., Olov Sterner, Echeverri, F. & Peter Zygmunt, 2010, In : Bioorganic & Medicinal Chemistry. 18, 9, p. 3299-3306

    Research output: Contribution to journalArticle

  26. TRPV1 in Brain Is Involved in Acetaminophen-Induced Antinociception

    Mallet, C., Barriere, D. A., Ermund, A., Jönsson, B. A., Eschalier, A., Peter Zygmunt & Högestätt, E., 2010, In : PLoS ONE. 5, 9

    Research output: Contribution to journalArticle

  27. 2009
  28. Transient receptor potential vanilloid 1, vanilloid 2 and melastatin 8 immunoreactive nerve fibers in human skin from individuals with and without Norrbottnian congenital insensitivity to pain.

    Axelsson, H. E., Minde, J. K., Sonesson, A., Toolanen, G., Högestätt, E. & Peter Zygmunt, 2009, In : Neuroscience. 162, p. 1322-1332

    Research output: Contribution to journalArticle

  29. TRPV1-mediated itch in seasonal allergic rhinitis.

    Lisa Alenmyr, Högestätt, E., Peter Zygmunt & Greiff, L., 2009, In : Allergy. 64, p. 807-810

    Research output: Contribution to journalArticle

  30. 2008
  31. Distribution and Function of the Hydrogen Sulfide-Sensitive TRPA1 Ion Channel in Rat Urinary Bladder

    Streng, T., Sturesson, H., Petter Hedlund, Andersson, D. A., Jordt, S-E., Bevan, S., Karl-Erik Andersson, Högestätt, E. & Peter Zygmunt, 2008, In : European Urology. 53, 2, p. 391-399

    Research output: Contribution to journalArticle

  32. 2005
  33. Conversion of acetaminophen to the bioactive N-acyl phenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous system.

    Högestätt, E., Jönsson, B. A., Ermund, A., Andersson, D., Björk, H., Alexander, J. P., Cravatt, B. F., Basbaum, A. I. & Peter Zygmunt, 2005, In : Journal of Biological Chemistry. 280, 36, p. 31405-31412

    Research output: Contribution to journalArticle

  34. Endogenous unsaturated C18 N-acylethanolamines are vanilloid receptor (TRPV1) agonists.

    Pouya Movahed Rad, Jönsson, B. A., Birnir, B., Wingstrand, J., Dyhring Jørgensen, T., Ermund, A., Olov Sterner, Peter Zygmunt & Högestätt, E., 2005, In : Journal of Biological Chemistry. 280, 46, p. 38496-38504

    Research output: Contribution to journalArticle

  35. Pungent products from garlic activate the sensory ion channel TRPA1

    Bautista, D. M., Pouya Movahed Rad, Hinman, A., Sturesson, H., Olov Sterner, Högestätt, E., Julius, D., Jordt, S. E. & Peter Zygmunt, 2005, In : Proceedings of the National Academy of Sciences. 102, 34, p. 12248-12252

    Research output: Contribution to journalArticle

  36. Vascular effects of anandamide and N-acylvanillylamines in the human forearm and skin microcirculation.

    Pouya Movahed Rad, Evilevitch, V., Andersson, T., Jönsson, B. A., Per Wollmer, Peter Zygmunt & Högestätt, E., 2005, In : British Journal of Pharmacology. 146, 2, p. 171-179

    Research output: Contribution to journalArticle

  37. 2004
  38. Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1

    Jordt, S-E., Bautista, D. M., Chuang, H., McKemy, D. D., Peter Zygmunt, Högestätt, E., Meng, I. D. & Julius, D., 2004, In : Nature. 427, 6971, p. 260-265

    Research output: Contribution to journalArticle

  39. 2002
  40. Δ9-Tetrahydrocannabinol and Cannabinol Activate Capsaicin-Sensitive Sensory Nerves via a CB1 and CB2 Cannabinoid Receptor-Independent Mechanism

    Peter M. Zygmunt, Andersson, D. A. & Högestätt, E. D., 2002 Jun 1, In : Journal of Neuroscience. 22, 11, p. 4720-4727 8 p.

    Research output: Contribution to journalArticle

  41. Cardiovascular pharmacology of anandamide.

    Högestätt, E. & Peter Zygmunt, 2002, In : Prostaglandins, Leukotrienes and Essential Fatty Acids. 66, 2-3, p. 343-351

    Research output: Contribution to journalReview article

  42. Mechanisms underlying tissue selectivity of anandamide and other vanilloid receptor agonists.

    Andersson, D., Adner, M., Högestätt, E. & Peter Zygmunt, 2002, In : Molecular Pharmacology. 62, 3, p. 705-713

    Research output: Contribution to journalArticle

  43. 2000
  44. The anandamide transport inhibitor AM404 activates vanilloid receptors

    Peter M. Zygmunt, Chuang, H. H., Movahed, P., Julius, D. & Högestätt, E. D., 2000 May 12, In : European Journal of Pharmacology. 396, 1, p. 39-42 4 p.

    Research output: Contribution to journalArticle

  45. Anandamide - The other side of the coin

    Peter M. Zygmunt, Julius, D., Högestätt, E. D. & Di Marzo, V., 2000 Feb 1, In : Trends in Pharmacological Sciences. 21, 2, p. 43-44

    Research output: Contribution to journalDebate/Note/Editorial

  46. Differential actions of anandamide, potassium ions and endothelium- derived hyperpolarizing factor in guinea-pig basilar artery

    Peter M. Zygmunt, Sørgård, M., Jesper Petersson, Johansson, R. & Högestätt, E. D., 2000 Jan 1, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 361, 5, p. 535-542 8 p.

    Research output: Contribution to journalArticle

  47. Involvement of sensory nerves in vasodilator responses to acetylcholine and potassium ions in rat hepatic artery

    Högestätt, E. D., Johansson, R., Andersson, D. A. & Peter M. Zygmunt, 2000 Jan 1, In : British Journal of Pharmacology. 130, 1, p. 27-32 6 p.

    Research output: Contribution to journalArticle

  48. Vanilloid receptors on capsaicin-sensitive sensory nerves mediate relaxation to methanandamide in the rat isolated mesenteric arterial bed and small mesenteric arteries

    Ralevic, V., Kendall, D. A., Randall, M. D., P. M. Zygmunt, Movahed, P. & Högestätt, E. D., 2000 Jan 1, In : British Journal of Pharmacology. 130, 7, p. 1483-1488 6 p.

    Research output: Contribution to journalArticle

  49. 1999
  50. Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide

    Peter M. Zygmunt, Jesper Petersson, Andersson, D. A., Chuang, H. H., Sørgård, M., Di Marzo, V., Julius, D. & Högestätt, E. D., 1999 Jul 29, In : Nature. 400, 6743, p. 452-457 6 p.

    Research output: Contribution to journalLetter

  51. 1998
  52. Interactions between endothelium-derived relaxing factors in the rat hepatic artery: Focus on regulation of EDHF

    Peter M. Zygmunt, Plane, F., Paulsson, M., Garland, C. J. & Högestätt, E. D., 1998 Jan 1, In : British Journal of Pharmacology. 124, 5, p. 992-1000 9 p.

    Research output: Contribution to journalArticle

  53. 1997
  54. Studies on the effects of anandamide in rat hepatic artery

    Peter M. Zygmunt, Högestätt, E. D., Waldeck, K., Edwards, G., Kirkup, A. J. & Weston, A. H., 1997 Dec 1, In : British Journal of Pharmacology. 122, 8, p. 1679-1686 8 p.

    Research output: Contribution to journalArticle

  55. Characterization of the potassium channels involved in EDHF-mediated relaxation in cerebral arteries

    Jesper Petersson, Peter M. Zygmunt & Högestätt, E. D., 1997 Apr 17, In : British Journal of Pharmacology. 120, 7, p. 1344-1350 7 p.

    Research output: Contribution to journalArticle

  56. Involvement of voltage-dependent potassium channels in the EDHF-mediated relaxation of rat hepatic artery

    Peter M. Zygmunt, Edwards, G., Weston, A. H., Larsson, B. & Högestätt, E. D., 1997 Jan 1, In : British Journal of Pharmacology. 121, 1, p. 141-149 9 p.

    Research output: Contribution to journalArticle

  57. Minor components with smooth muscle relaxing properties from scented myrrh (Commiphora guidotti)

    Andersson, M., Ola Bergendorff, Shan, R., Peter Zygmunt & Olov Sterner, 1997, In : Planta Medica. 63, 3, p. 251-254

    Research output: Contribution to journalArticle

  58. 1996
  59. Effects of cytochrome P450 inhibitors on EDHF-mediated relaxation in the rat hepatic artery

    Peter M. Zygmunt, Edwards, G., Weston, A. H., Davis, S. C. & Högestätt, E. D., 1996 Jan 1, In : British Journal of Pharmacology. 118, 5, p. 1147-1152 6 p.

    Research output: Contribution to journalArticle

  60. Effects of cytochrome P450 inhibitors on potassium currents and mechanical activity in rat portal vein

    Edwards, G., Peter M. Zygmunt, Högestätt, E. D. & Weston, A. H., 1996 Jan 1, In : British Journal of Pharmacology. 119, 4, p. 691-701 11 p.

    Research output: Contribution to journalArticle

  61. Role of potassium channels in endothelium-dependent relaxation resistant to nitroarginine in the rat hepatic artery

    Peter M. Zygmunt & Högestätt, E. D., 1996 Jan 1, In : British Journal of Pharmacology. 117, 7, p. 1600-1606 7 p.

    Research output: Contribution to journalArticle

  62. 1995
  63. Substance P-induced relaxation and hyperpolarization in human cerebral arteries

    Jesper Petersson, Peter M Zygmunt, Brandt, L. & Högestätt, E. D., 1995 Jul, In : British Journal of Pharmacology. 115, 6, p. 889-94

    Research output: Contribution to journalArticle

  64. NANC neurotransmission in lamina propria of the rabbit urethra: regulation by different subsets of calcium channels

    Zygmunt, P. K. E., Peter M. Zygmunt, Högestätt, E. D. & Karl‐Erik Andersson, 1995 Jan 1, In : British Journal of Pharmacology. 115, 6, p. 1020-1026 7 p.

    Research output: Contribution to journalArticle

  65. Regional differences in endothelium‐dependent relaxation in the rat: contribution of nitric oxide and nitric oxide‐independent mechanisms

    P. M. ZYGMUNT, RYMAN, T. & HÖGESTÄTT, E. D., 1995 Jan 1, In : Acta Physiologica Scandinavica. 155, 3, p. 257-266 10 p.

    Research output: Contribution to journalArticle

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