Rashmi Prasad

Associate Researcher
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  1. 2019
  2. Loss of MafA and MafB expression promotes islet inflammation.

    Tania Singh, Colberg, J. K., Luis Sarmiento, Chaves, P., Hansen, L., Bsharat, S., Luis R. Cataldo, Monika Dudenhöffer-Pfeifer, Malin Fex, David Bryder, Dan Holmberg, Ewa Sitnicka, Corrado Cilio, Rashmi B. Prasad & Isabella Artner, 2019 Jun 24, In : Scientific Reports. 9, 1, 9074.

    Research output: Contribution to journalArticle

  3. FOETAL for NCD-FOetal Exposure and Epidemiological Transitions: the role of Anaemia in early Life for Non-Communicable Diseases in later life: a prospective preconception study in rural Tanzania

    Line Hjort, Lykke Møller, S., Minja, D., Msemo, O., Nielsen, B. B., Lund Christensen, D., Theander, T., Nielsen, K., Larsen, L. G., Grunnet, L. G., Leif Groop, Rashmi Prasad, Lusingu, J., Schmiegelow, C. & Bygbjerg, I. C., 2019 May 22, In : BMJ Open. 9, 5, e024861.

    Research output: Contribution to journalArticle

  4. Phenotypic and genotypic differences between Indian and Scandinavian women with gestational diabetes mellitus

    Geeti P Arora, Mikael Åkerlund, Brøns, C., Moen, G-H., Wasenius, N. S., Sommer, C., Jenum, A. K., Almgren, P., Thaman, R. G., Marju Orho-Melander, Eriksson, J., Qvigstad, E., Birkeland, K., Kerstin Berntorp, Allan A Vaag, Leif Groop & Rashmi B Prasad, 2019 Mar 27, In : Journal of Internal Medicine.

    Research output: Contribution to journalArticle

  5. The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects

    Middeldorp, C. M., Leif Groop, Rashmi Prasad, McCarthy, M. I., Emma Ahlqvist, EArly Genetics Lifecourse Epidemiology (EAGLE) consortium & Early Growth Genetics (EGG) consortium, 2019 Mar, In : European Journal of Epidemiology. 34, 3, p. 279-300

    Research output: Contribution to journalArticle

  6. Genome editing of human pancreatic beta cell models: problems, possibilities and outlook

    Balboa, D., Rashmi B Prasad, Leif Groop & Otonkoski, T., 2019, In : Diabetologia. 62, 8, p. 1329-1336

    Research output: Contribution to journalReview article

  7. Precision medicine in Type 2 Diabetes

    Rashmi B Prasad & Leif Groop, 2019, In : Journal of Internal Medicine. 285, 1, p. 40-48

    Research output: Contribution to journalReview article

  8. RORB and RORC associate with human islet dysfunction and inhibit insulin secretion in INS-1 cells

    Taneera, J., Mohammed, A. K., Dhaiban, S., Hamad, M., Rashmi B. Prasad, Sulaiman, N. & Albert Salehi, 2019, In : Islets. 11, 1, p. 10-20 11 p.

    Research output: Contribution to journalArticle

  9. 2018
  10. Turning vice into virtue: Using Batch-Effects to Detect Errors in Large Genomic Datasets

    Mafessoni, F., Rashmi B Prasad, Leif Groop, Ola Hansson & Prüfer, K., 2018 Sep 10, In : Genome Biology and Evolution. 10, 10, p. 2697–2708

    Research output: Contribution to journalArticle

  11. Association between genetic risk variants and glucose intolerance during pregnancy in north Indian women

    Geeti Arora, Almgren, P., Brøns, C., Thaman, R. G., Allan Vaag, Leif Groop & Rashmi Prasad, 2018 Aug 8, In : BMC Medical Genomics. 11, 10 p., 64.

    Research output: Contribution to journalArticle

  12. Controllability in an islet specific regulatory network identifies the transcriptional factor NFATC4, which regulates Type 2 Diabetes associated genes

    Sharma, A., Halu, A., Decano, J. L., Padi, M., Liu, Y., Rashmi B. Prasad, Fadista, J., Santolini, M., Menche, J., Weiss, S. T., Vidal, M., Silverman, E. K., Aikawa, M., Barabási, A., Leif Groop & Loscalzo, J., 2018 Jul 3, In : npj Systems Biology and Applications. 4, 1, 25.

    Research output: Contribution to journalArticle

  13. Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes

    Gusarova, V., O'Dushlaine, C., Teslovich, T. M., Benotti, P. N., Mirshahi, T., Gottesman, O., Van Hout, C. V., Murray, M. F., Mahajan, A., Nielsen, J. B., Fritsche, L., Wulff, A. B., Gudbjartsson, D. F., Sjögren, M., Emdin, C. A., Scott, R. A., Lee, W-J., Small, A., Kwee, L. C., Dwivedi, O. P. & 61 othersRashmi B Prasad, Bruse, S., Lopez, A. E., Penn, J., Marcketta, A., Leader, J. B., Still, C. D., Kirchner, H. L., Mirshahi, U. L., Wardeh, A. H., Hartle, C. M., Habegger, L., Fetterolf, S. N., Tusie-Luna, T., Morris, A. P., Holm, H., Steinthorsdottir, V., Sulem, P., Thorsteinsdottir, U., Rotter, J. I., Chuang, L-M., Damrauer, S., Birtwell, D., Brummett, C. M., Khera, A. V., Natarajan, P., Marju Orho-Melander, Flannick, J., Lotta, L. A., Willer, C. J., Holmen, O. L., Ritchie, M. D., Ledbetter, D. H., Murphy, A. J., Borecki, I. B., Reid, J. G., Overton, J. D., Ola Hansson, Leif Groop, Shah, S., Kraus, W. E., Rader, D. J., Ida Chen, Y-D., Hveem, K., Wareham, N. J., Kathiresan, S., Olle Melander, Stefansson, K., Nordestgaard, B. G., Tybjaerg-Hansen, A., Abecasis, G. R., Altshuler, D., Florez, J. C., Boehnke, M., McCarthy, M., Yancopoulos, G. D., Carey, D. J., Shuldiner, A. R., Baras, A., Dewey, F. E. & Gromada, J., 2018 Jun 13, In : Nature Communications. 9, p. 1-11 2252.

    Research output: Contribution to journalArticle

  14. Novel diabetes subgroups – Authors' reply

    Emma Ahlqvist, Rashmi B. Prasad, Tuomi, T., Anders Rosengren & Leif Groop, 2018 Jun 1, In : The Lancet Diabetes and Endocrinology. 6, 6, p. 440-441 2 p.

    Research output: Contribution to journalLetter

  15. Haplotype Sharing Provides Insights into Fine-Scale Population History and Disease in Finland

    Martin, A. R., Karczewski, K. J., Kerminen, S., Kurki, M. I., Sarin, A-P., Artomov, M., Eriksson, J. G., Esko, T., Genovese, G., Havulinna, A. S., Kaprio, J., Konradi, A., Korányi, L., Kostareva, A., Männikkö, M., Metspalu, A., Perola, M., Prasad, R. B., Raitakari, O., Rotar, O. & 7 othersSalomaa, V., Leif Groop, Palotie, A., Neale, B. M., Ripatti, S., Pirinen, M. & Daly, M. J., 2018 May, In : American Journal of Human Genetics. 102, 5, p. 760-775 16 p.

    Research output: Contribution to journalArticle

  16. Novel subgroups of adult-onset diabetes and their association with outcomes: A data-driven cluster analysis of six variables

    Ahlqvist, E., Storm, P., Käräjämäki, A., Martinell, M., Dorkhan, M., Carlsson, A., Vikman, P., Prasad, R. B., Aly, D. M., Almgren, P., Wessman, Y., Shaat, N., Spégel, P., Mulder, H., Lindholm, E., Melander, O., Hansson, O., Malmqvist, U., Lernmark, Å., Lahti, K. & 4 othersForsén, T., Tuomi, T., Anders H. Rosengren & Leif Groop, 2018 May, In : The Lancet Diabetes and Endocrinology. 6, 5, p. 361-369

    Research output: Contribution to journalArticle

  17. Genetics of Diabetes and Diabetic Complications

    Rashmi Prasad, Emma Ahlqvist & Leif Groop, 2018 Mar 16, Diabetes. Epidemiology, Genetics, Pathogenesis, Diagnosis, Prevention, and Treatment. Bonora, E. & DeFronzo, R. (eds.). Springer, 60 p. (Endocrinology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

  18. Genetic determinants of glucose levels in pregnancy: Genetic risk scores analysis and GWAS in the Norwegian STORK cohort

    Moen, G. H., LeBlanc, M., Sommer, C., Rashmi B. Prasad, Lekva, T., Normann, K. R., Qvigstad, E., Leif Groop, Birkeland, K. I., Evans, D. M. & Frøslie, K. F., 2018, In : European journal of endocrinology. 179, 6, p. 363-372 10 p.

    Research output: Contribution to journalArticle

  19. Role of osteopontin and its regulation in pancreatic islet

    Cai, M., Pradeep Bompada, Albert Salehi, Acosta, J. R., Rashmi B. Prasad, Atac, D., Laakso, M., Leif Groop & Yang De Marinis, 2018, In : Biochemical and Biophysical Research Communications. 495, 1, p. 1426-1431

    Research output: Contribution to journalArticle

  20. Silencing of the FTO gene inhibits insulin secretion: An in vitro study using GRINCH cells

    Taneera, J., Rashmi B Prasad, Dhaiban, S., Mohammed, A. K., Haataja, L., Arvan, P., Hamad, M., Leif Groop & Claes B Wollheim, 2018, In : Molecular and Cellular Endocrinology. 472, p. 10-17

    Research output: Contribution to journalArticle

  21. 2017
  22. Genetic determinants of circulating GIP and GLP-1 concentrations

    Almgren, P., Andreas Lindqvist, Krus, U., Hakaste, L. H., Ottosson Laakso, E., Olof Asplund, Emily Sonestedt, Rashmi Prasad, Esa Laurila, Marju Orho-Melander, Olle Melander, Tuomi, T., Juul Holst, J., Peter Nilsson, Nils Wierup, Leif Groop & Emma Ahlqvist, 2017 Nov 2, In : JCI Insight. 2, 21, e93306.

    Research output: Contribution to journalArticle

  23. Insulin secretion and action in North Indian women during pregnancy

    G. P. Arora, Almgren, P., Thaman, R. G., Pal, A., Leif Groop, A Vaag, R B Prasad & Brøns, C., 2017 Oct, In : Diabetic medicine : a journal of the British Diabetic Association. 34, 10, p. 1477-1482

    Research output: Contribution to journalArticle

  24. Epigenetic modifications and gestational diabetes: A Systematic review of published literature

    Moen, G. H., Sommer, C., Rashmi B. Prasad, Sletner, L., Leif Groop, Qvigstad, E. & Birkeland, K. I., 2017 May 1, In : European Journal of Endocrinology. 176, 5, p. R247-R267

    Research output: Contribution to journalReview article

  25. Genetic Architecture of Type 2 Diabetes

    Rashmi B. Prasad & Leif Groop, 2017, Textbook of Diabetes. Holt, R. I. G., Cockram, C., Flyvbjerg, A. & Goldstein, B. J. (eds.). 5 ed. Wiley-Blackwell

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

  26. Glucose-induced Changes in Gene Expression in Human Pancreatic Islets - Causes or Consequences of Chronic Hyperglycemia

    Ottosson-Laakso, E., Krus, U., Storm, P., Rashmi B Prasad, Nikolay Oskolkov, Emma Ahlqvist, Fadista, J., Ola Hansson, Leif Groop & Petter Vikman, 2017, In : Diabetes. 66, 12, p. 3013-3028

    Research output: Contribution to journalArticle

  27. 2016
  28. Single-Cell Sequencing of Human Pancreatic Islets—New Kids on the Block

    Rashmi B. Prasad & Leif Groop, 2016 Oct 11, In : Cell Metabolism. 24, 4, p. 523-524 2 p.

    Research output: Contribution to journalArticle

  29. Excess maternal transmission of variants in the THADA gene to offspring with type 2 diabetes

    Prasad, R. B., Lessmark, A., Almgren, P., Kovacs, G., Hansson, O., Oskolkov, N., Vitai, M., Ladenvall, C., Kovacs, P., Fadista, J., Lachmann, M., Zhou, Y., Sonestedt, E., Poon, W., Wollheim, C. B., Orho-Melander, M., Stumvoll, M., Tuomi, T., Pääbo, S., Koranyi, L. & 1 othersLeif Groop, 2016 Aug, In : Diabetologia. 59, 8, p. 1702-1713 12 p.

    Research output: Contribution to journalArticle

  30. 2015
  31. Genetics of type 2 diabetes: It matters from which parent we inherit the risk

    Valeriya Lyssenko, Leif Groop & Rashmi B. Prasad, 2015, In : Review of Diabetic Studies. 12, 3-4, p. 233-242 10 p.

    Research output: Contribution to journalReview article

  32. Genetics of type 2 diabetes-pitfalls and possibilities.

    Rashmi Prasad & Leif Groop, 2015, In : Genes. 6, 1, p. 87-123

    Research output: Contribution to journalReview article

  33. 2014
  34. A Central Role for GRB10 in Regulation of Islet Function in Man.

    Prokopenko, I., Poon, W., Mägi, R., Prasad, R., Salehi, S. A., Almgren, P., Osmark, P., Bouatia-Naji, N., Wierup, N., Fall, T., Stančáková, A., Barker, A., Lagou, V., Osmond, C., Xie, W., Lahti, J., Jackson, A. U., Cheng, Y-C., Liu, J., O'Connell, J. R. & 44 othersBlomstedt, P. A., Fadista, J., Alkayyali, S., Dayeh, T., Emma Ahlqvist, Taneera, J., Lecoeur, C., Kumar, A., Ola Hansson, Karin B Hansson, F Voight, B., Kang, H. M., Levy-Marchal, C., Vatin, V., Palotie, A., Syvänen, A-C., Mari, A., Weedon, M. N., Loos, R. J. F., Ong, K. K., Peter Nilsson, Isomaa, B., Tuomi, T., Wareham, N. J., Stumvoll, M., Widen, E., Lakka, T. A., Langenberg, C., Tönjes, A., Rauramaa, R., Kuusisto, J., Frayling, T. M., Froguel, P., Walker, M., Eriksson, J. G., Charlotte Ling, Kovacs, P., Ingelsson, E., McCarthy, M. I., Shuldiner, A. R., Silver, K. D., Laakso, M., Leif Groop & Valeriya Lyssenko, 2014, In : PLoS Genetics. 10, 4, e1004235.

    Research output: Contribution to journalArticle

  35. Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism.

    Fadista, J., Vikman, P., Ottosson Laakso, E., Mollet, I., Esguerra, J., Taneera, J., Storm, P., Osmark, P., Ladenvall, C., Prasad, R., Hansson, K. B., Finotello, F., Uvebrant, K., Ofori, J., Di Camillo, B., Krus, U., Cilio, C., Hansson, O., Eliasson, L., Rosengren, A. & 3 othersErik Renström, Claes Wollheim & Leif Groop, 2014, In : Proceedings of the National Academy of Sciences. 111, 38, p. 13924-13929

    Research output: Contribution to journalArticle

  36. 2011
  37. MTHFR and MTRR genotype and haplotype analysis and colorectal cancer susceptibility in a case?control study from the Czech Republic

    Pardini, B., Kumar, R., Naccarati, A., Rashmi B. Prasad, Forsti, A., Polakova, V., Vodickova, L., Novotny, J., Kari Hemminki & Vodicka, P., 2011 Mar 1, In : Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 721, 1, p. 74-80

    Research output: Contribution to journalArticle

  38. 5-Fluorouracil-based chemotherapy for colorectal cancer and MTHFR/MTRR genotypes.

    Pardini, B., Kumar, R., Naccarati, A., Novotny, J., Rashmi B. Prasad, Asta Försti, Kari Hemminki, Vodicka, P. & Bermejo, J. L., 2011, In : British Journal of Clinical Pharmacology. 72, p. 162-163

    Research output: Contribution to journalLetter

  39. 2010
  40. Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk

    Sherborne, A. L., Hosking, F. J., Prasad, R. B., Kumar, R., Koehler, R., Vijayakrishnan, J., Papaemmanuil, E., Bartram, C. R., Stanulla, M., Schrappe, M., Gast, A., Dobbins, S. E., Ma, Y., Sheridan, E., Taylor, M., Kinsey, S. E., Lightfoot, T., Roman, E., Irving, J. A. E., Allan, J. M. & 18 othersMoorman, A. V., Harrison, C. J., Tomlinson, I. P., Richards, S., Zimmermann, M., Szalai, C., Semsei, A. F., Erdelyi, D. J., Krajinovic, M., Sinnett, D., Healy, J., Gonzalez-Neira, A., Kawamata, N., Ogawa, S., Koeffler, H. P., Kari Hemminki, Greaves, M. & Houlston, R. S., 2010 Jun, In : Nature Genetics. 42, 6, p. 492-4 3 p.

    Research output: Contribution to journalArticle

  41. Verification of the susceptibility loci on 7p12.2, 10q21.2, and 14q11.2 in precursor B-cell acute lymphoblastic leukemia of childhood

    Rashmi B Prasad, Hosking, F. J., Vijayakrishnan, J., Papaemmanuil, E., Koehler, R., Greaves, M., Sheridan, E., Gast, A., Kinsey, S. E., Lightfoot, T., Roman, E., Taylor, M., Pritchard-Jones, K., Stanulla, M., Schrappe, M., Bartram, C. R., Houlston, R. S., Kumar, R. & Kari Hemminki, 2010 Mar 4, In : Blood. 115, 9, p. 1765-7 3 p.

    Research output: Contribution to journalArticle

  42. 2005
  43. A manually curated functional annotation of the human X chromosome

    Harsha, H. C., Suresh, S., Amanchy, R., Deshpande, N., Shanker, K., Yatish, A. J., Muthusamy, B., Vrushabendra, B. M., Rashmi, B. P., Chandrika, K. N., Padma, N., Sharma, S., Badano, J. L., Ramya, M. A., Shivashankar, H. N., Peri, S., Choudhury, D. R., Kavitha, M. P., Saravana, R., Niranjan, V. & 11 othersGandhi, T. K. B., Ghosh, N., Chandran, S., Menezes, M., Joy, M., Mohan, S. S., Katsanis, N., Deshpande, K. S., Raghothama, C., Prasad, C. K. & Pandey, A., 2005 Apr, In : Nature Genetics. 37, 4, p. 331-2 2 p.

    Research output: Contribution to journalDebate/Note/Editorial

  44. 2004
  45. BioBuilder as a database development and functional annotation platform for proteins

    Navarro, J. D., Talreja, N., Peri, S., Vrushabendra, B. M., BP Rashmi, Padma, N., Surendranath, V., Jonnalagadda, C. K., Kousthub, P. S., Deshpande, N., Shanker, K. & Pandey, A., 2004 Apr 20, In : BMC Bioinformatics. 5, 43.

    Research output: Contribution to journalArticle

  46. Human protein reference database as a discovery resource for proteomics

    Peri, S., Navarro, J. D., Kristiansen, T. Z., Amanchy, R., Surendranath, V., Muthusamy, B., Gandhi, T. K. B., Chandrika, K. N., Deshpande, N., Suresh, S., Rashmi, B. P., Shanker, K., Padma, N., Niranjan, V., Harsha, H. C., Talreja, N., Vrushabendra, B. M., Ramya, M. A., Yatish, A. J., Joy, M. & 13 othersShivashankar, H. N., Kavitha, M. P., Menezes, M., Choudhury, D. R., Ghosh, N., Saravana, R., Chandran, S., Mohan, S. S., Jonnalagadda, C. K., Prasad, C. K., Kumar-Sinha, C., Deshpande, K. S. & Pandey, A., 2004 Jan 1, In : Nucleic Acids Research. 32, Database issue, p. D497-501

    Research output: Contribution to journalArticle

  47. 2003
  48. Development of human protein reference database as an initial platform for approaching systems biology in humans

    Peri, S., Navarro, J. D., Amanchy, R., Kristiansen, T. Z., Jonnalagadda, C. K., Surendranath, V., Niranjan, V., Muthusamy, B., Gandhi, T. K. B., Gronborg, M., Ibarrola, N., Deshpande, N., Shanker, K., Shivashankar, H. N., Rashmi, B. P., Ramya, M. A., Zhao, Z., Chandrika, K. N., Padma, N., Harsha, H. C. & 32 othersYatish, A. J., Kavitha, M. P., Menezes, M., Choudhury, D. R., Suresh, S., Ghosh, N., Saravana, R., Chandran, S., Krishna, S., Joy, M., Anand, S. K., Madavan, V., Joseph, A., Wong, G. W., Schiemann, W. P., Constantinescu, S. N., Huang, L., Khosravi-Far, R., Steen, H., Tewari, M., Ghaffari, S., Blobe, G. C., Dang, C. V., Garcia, J. G. N., Pevsner, J., Jensen, O. N., Roepstorff, P., Deshpande, K. S., Chinnaiyan, A. M., Hamosh, A., Chakravarti, A. & Pandey, A., 2003 Oct, In : Genome Research. 13, 10, p. 2363-71 9 p.

    Research output: Contribution to journalArticle