Signe Borgquist

Visiting Professor, MD, PhD, Associate Professor
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  1. 2021
  2. Low-Dose Tamoxifen for Mammographic Density Reduction: A Randomized Controlled Trial

    Mikael Eriksson, Martin Eklund, Signe Borgquist, Roxanna Hellgren, Sara Margolin, Linda Thoren, Ann Rosendahl, Kristina Lång, José Tapia, Magnus Bäcklund, Andrea Discacciati, Alessio Crippa, Marike Gabrielson, Mattias Hammarström, Yvonne Wengström, Kamila Czene & Per Hall, 2021 Mar 18, In: Journal of Clinical Oncology. JCO2002598.

    Research output: Contribution to journalArticle

  3. Dietary intake of trans fatty acids and breast cancer risk in 9 European countries

    Michèle Matta, Inge Huybrechts, Carine Biessy, Corinne Casagrande, Sahar Yammine, Agnès Fournier, Karina Standahl Olsen, Marco Lukic, Inger Torhild Gram, Eva Ardanaz, Maria José Sánchez, Laure Dossus, Renée T. Fortner, Bernard Srour, Franziska Jannasch, Matthias B. Schulze, Pilar Amiano, Antonio Agudo, Sandra Colorado-Yohar, J. Ramón Quirós & 18 others, Rosario Tumino, Salvatore Panico, Giovanna Masala, Valeria Pala, Carlotta Sacerdote, Anne Tjønneland, Anja Olsen, Christina C. Dahm, Ann H. Rosendahl, Signe Borgquist, Maria Wennberg, Alicia K. Heath, Dagfinn Aune, Julie Schmidt, Elisabete Weiderpass, Veronique Chajes, Marc J. Gunter & Neil Murphy, 2021, In: BMC Medicine. 19, 1, 81.

    Research output: Contribution to journalArticle

  4. 2020
  5. Statin use and breast cancer recurrence in postmenopausal women treated with adjuvant aromatase inhibitors: a Danish population-based cohort study

    Sixten Harborg, Uffe Heide-Jørgensen, Thomas P. Ahern, Marianne Ewertz, Deirdre Cronin-Fenton & Signe Borgquist, 2020 Aug, In: Breast Cancer Research and Treatment. 183, 1, p. 153-160 8 p.

    Research output: Contribution to journalArticle

  6. Abstract P5-02-01: Analytical validation and prognostic potential of an automated digital scoring protocol for Ki67: An International Ki67 Working Group study

    Balazs Acs, Samuel CY Leung, Kelley M. Kidwell, Indu Arun, Renaldas Augulis, Sunil S Badve, Yalai Bai, Anita L. Bane, John Bartlett, Jane Bayani, Gilbert Bigras, Annika Blank, Signe Borgquist, Henk Buikema, Martin C. Chang, Robin L. Dietz, Andrew Dodson, Anna Ehinger, Susan Fineberg, Cornelia Focke & 34 others, Dongxia Gao, Allen M Gown, Carolina Gutierrez, Johan Hartman, Judith C Hugh, Zuzana Kos, Anne Vibeke Laenkholm, Arvydas Laurinavicius, Richard M. Levenson, Rustin Mahboubi-Ardakani, Mauro G Mastropasqua, Takuya Moriya, Sharon Nofech-Mozes, C Kent Osborne, Liron Pantanowitz, Frédérique M Penault-Llorca, Tammy Piper, Mary Anne Quintayo, Tilman T. Rau, Stefan Reinhard, Stephanie Robertson, Takashi Sakatani, Roberto Salgado, Melanie Spears, Jane Starczynski, Tomoharu Sugie, Bert van der Vegt, Giuseppe Viale, Shakeel Virk, Lila A Zabaglo, Daniel F Hayes, Mitch Dowsett, Torsten O Nielsen & David L. Rimm, 2020 Feb, In: Cancer research. Supplement. 80, 4 Suppl, P5-02-01.

    Research output: Contribution to journalPublished meeting abstract

  7. Investigating the risk of breast cancer among women exposed to chemicals: a nested case–control study using improved exposure estimates

    Cecilia Videnros, Jenny Selander, Pernilla Wiebert, Maria Albin, Nils Plato, Signe Borgquist, Jonas Manjer & Per Gustavsson, 2020 Feb, In: International Archives of Occupational and Environmental Health. 93, 2, p. 261-269 9 p.

    Research output: Contribution to journalArticle

  8. Hypoxia attenuates trastuzumab uptake and trastuzumab-emtansine (T-DM1) cytotoxicity through redistribution of phosphorylated caveolin-1

    Vineesh Indira Chandran, Ann Sofie Mansson, Magdalena Barbachowska, Myriam Cerezo-Magana, Bjorn Nodin, Bharat Joshi, Neelima KoppaD.A., Ola M. Saad, Oleg Gluz, Karolin Isaksson, Signe Borgquist, Karin Jirstrom, Ivan Robert Nabi, Helena Jernstrom & Mattias Belting, 2020, In: Molecular Cancer Research. 18, 4, p. 644-656 13 p.

    Research output: Contribution to journalArticle

  9. Markers of steroid receptor, kinase signalling pathways and Ki-67 expression in relation to tamoxifen sensitivity and resistance

    Christine Campbell, John Mathew, Ian O. Ellis, Ian Bradbury, Signe Borgquist, Karin Elebro, Andrew R. Green, Pauline Finlay, Julia M. W. Gee & John F. R. Robertson, 2020, In: Translational Breast Cancer Research. 1, 29.

    Research output: Contribution to journalArticle

  10. Tumour-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression

    Ori Maller, Allison P. Drain, Alexander S. Barrett, Signe Borgquist, Brian Ruffell, Igor Zakharevich, Thanh T. Pham, Tina Gruosso, Hellen Kuasne, Johnathon N. Lakins, Irene Acerbi, J. Matthew Barnes, Travis Nemkov, Aastha Chauhan, Jessica Gruenberg, Aqsa Nasir, Olof Bjarnadottir, Zena Werb, Peter Kabos, Yunn Yi Chen & 6 others, E. Shelley Hwang, Morag Park, Lisa M. Coussens, Andrew C. Nelson, Kirk C. Hansen & Valerie M. Weaver, 2020, In: Nature Materials.

    Research output: Contribution to journalArticle

  11. 2019
  12. Analytical validation of a standardized scoring protocol for Ki67 immunohistochemistry on breast cancer excision whole sections: an international multicenter collaboration

    Samuel CY Leung, Torsten Nielsen, Lila A Zabaglo, Indu Arun, Sunil S Badve, Anita L Bane, John Bartlett, Signe Borgquist, Martin C Chang, A Dodson, Anna Ehinger, Susan Fineberg, Cornelia Focke, Dongxia Gao, Allen M Gown, Carolina Gutierrez, Judith C Hugh, Zuzana Kos, Anne Vibeke Laenkholm, Mauro G Mastropasqua & 14 others, Takuya Moriya, Sharon Nofech-Mozes, C Kent Osborne, Frédérique M Penault-Llorca, Tammy Piper, Takashi Sakatani, Roberto Salgado, Jane Starczynski, Tomoharu Sugie, Bert van der Vegt, Giuseppe Viale, Daniel Hayes, Lisa M McShane & Mitch Dowsett, 2019 Aug, In: Histopathology. 75, 2, p. 225-235 11 p.

    Research output: Contribution to journalArticle

  13. Statin use and breast cancer survival - A Swedish nationwide study

    Signe Borgquist, Per Broberg, Jasaman Tojjar & Håkan Olsson, 2019 Jan 11, In: BMC Cancer. 19, 1, 54.

    Research output: Contribution to journalArticle

  14. Circulating lipids, mammographic density, and risk of breast cancer in the Nurses’ Health Study and Nurses’ Health Study II

    Sarah A. Lucht, A. Heather Eliassen, Kimberly A. Bertrand, Thomas P. Ahern, Signe Borgquist, Bernard Rosner, Susan E. Hankinson & Rulla M. Tamimi, 2019, In: Cancer Causes and Control. 30, 9, p. 943–953

    Research output: Contribution to journalArticle

  15. The impact of body size changes on recurrence risk depends on age and estrogen receptor status in primary breast cancer

    Helga Tryggvadottir, Maria Ygland Rödström, Andrea Markkula, Xuyian Kenéz, Karolin Isaksson, Signe Borgquist & Helena Jernström, 2019, In: Cancer causes & control : CCC. 30, 11, p. 1157-1170 14 p.

    Research output: Contribution to journalArticle

  16. 2018
  17. Interactions between ABCB1genotype and preoperative statin use impact clinical outcomes among breast cancer patients

    Helga Tryggvadottir, Louise Huzell, Emma Gustbée, Maria Simonsson, Andrea Markkula, Karin Jirström, Carsten Rose, Christian Ingvar, Signe Borgquist & Helena Jernström, 2018 Oct 12, In: Frontiers in Oncology. 8, OCT

    Research output: Contribution to journalArticle

  18. Statins: a role in breast cancer therapy?

    S. Borgquist, O. Bjarnadottir, S. Kimbung & T. P. Ahern, 2018 Oct 1, In: Journal of Internal Medicine. 284, 4, p. 346-357 12 p.

    Research output: Contribution to journalReview article

  19. Long-term exposure to insulin and volumetric mammographic density: Observational and genetic associations in the Karma study

    Signe Borgquist, Ann H. Rosendahl, Kamila Czene, Nirmala Bhoo-Pathy, Mozhgan Dorkhan, Per Hall & Judith S. Brand, 2018 Aug 9, In: Breast Cancer Research. 20, 1, 93.

    Research output: Contribution to journalArticle

  20. Association of statin usewith overall and cancer survival

    Thomas P. Ahern, Signe Borgquist & Deirdre P. Cronin-Fenton, 2018 Jul 1, In: JAMA oncology. 4, 7, p. 1015-1016

    Research output: Contribution to journalLetter

  21. Towards prevention of breast cancer: What are the clinical challenges?

    Signe Borgquist, Per Hall, Isaac Lipkus & Judy E. Garber, 2018 May 1, In: Cancer Prevention Research. 11, 5, p. 255-264 10 p.

    Research output: Contribution to journalReview article

  22. Abstract P2-03-01: Analytical validation of a standardized scoring protocol for Ki67 assessed on breast excision whole sections: An international multicenter collaboration

    Torsten O Nielsen, Samuel CY Leung, LA Zabaglo, I Arun, SS Badve, AL Bane, JMS Bartlet, Signe Borgquist, MC Chang, A Dodson, Anna Ehinger, S Fineberg, CM Focke, D Gao, Allen M Gown, Carolina Gutierrez, JC Hugh, Z Kos, Anne-Vibeke Lænkholm, Mauro G Mastropasqua & 14 others, Takuya Moriya, S Nofech-Mozes, CK Osborne, Frédérique M Penault-Llorca, Tammy Piper, Takashi Sakatani, Roberto Salgado, Jane Starczynski, T Sugie, B van der Vegt, Giuseppe Viale, Daniel F Hayes, Lisa M McShane & Mitch Dowsett, 2018 Feb, In: Cancer research. Supplement. 78, 4

    Research output: Contribution to journalPublished meeting abstract

  23. A comprehensive analysis of polymorphic variants in steroid hormone and insulin-like growth factor-1 metabolism and risk of in situ breast cancer: Results from the Breast and Prostate Cancer Cohort Consortium

    Myrto Barrdahl, Federico Canzian, Mia M. Gaudet, Susan M. Gapstur, Antonia Trichopoulou, Kostas Tsilidis, Carla H. van Gils, Signe Borgquist, Elisabete Weiderpass, Kay Tee Khaw, Graham G. Giles, Roger L. Milne, Loic Le Marchand, Christopher Haiman, Sara Lindström, Peter Kraft, David J. Hunter, Regina Ziegler, Stephen J. Chanock, Xiaohong R. Yang & 4 others, Julie E. Buring, I. Min Lee, Rudolf Kaaks & Daniele Campa, 2018, In: International Journal of Cancer. 142, 6, p. 1182-1188

    Research output: Contribution to journalArticle

  24. 2017
  25. Cohort Profile: The Karolinska Mammography Project for Risk Prediction of Breast Cancer (KARMA)

    Marike Gabrielson, Mikael Eriksson, Mattias Hammarström, Signe Borgquist, Karin Leifland, Kamila Czene & Per Hall, 2017 Dec 1, In: International Journal of Epidemiology. 46, 6, p. 1740–1741g

    Research output: Contribution to journalArticle

  26. Impact of 27-hydroxylase (CYP27A1) and 27-hydroxycholesterol in breast cancer

    Siker Kimbung, Ching-Yi Chang, Pär-Ola Bendahl, Laura Dubois, J Will Thompson, Donald P McDonnell & Signe Borgquist, 2017 Jul, In: Endocrine-Related Cancer. 24, 7, p. 339-349 11 p.

    Research output: Contribution to journalArticle

  27. Cholesterol, cholesterol-lowering medication use, and breast cancer outcome in the BIG 1-98 study

    Signe Borgquist, Anita Giobbie-Hurder, Thomas P Ahern, Judy E Garber, Marco Colleoni, István Láng, Marc Debled, Bent Ejlertsen, Roger Von Moos, Ian E. Smith, Alan S. Coates, Aron Goldhirsch, Manuela Rabaglio, Karen N. Price, Richard D. Gelber, Meredith M. Regan & Beat Thürlimann, 2017 Apr 10, In: Journal of Clinical Oncology. 35, 11, p. 1179-1188 10 p.

    Research output: Contribution to journalArticle

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