Sofia Gruvberger

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  1. 2016
  2. Integrated molecular pathway analysis informs a synergistic combination therapy targeting PTEN/PI3K and EGFR pathways for basal-like breast cancer

    She, Q. B., Sofia Gruvberger, Maurer, M., Yilun Chen, Jumppanen, M., Su, T., Dendy, M., Lau, Y. K. I., Memeo, L., Horlings, H. M., van de Vijver, M. J., Isola, J., Hibshoosh, H., Rosen, N., Parsons, R. & Lao H. Saal, 2016 Aug 2, In : BMC Cancer. 16, 1, 587.

    Research output: Contribution to journalArticle

  3. 2015
  4. Whole genome sequencing of primary breast cancers and matched distant metastases

    Tang, M-H. E., Malin Dahlgren, Christian Brueffer, Winter, C., Yilun Chen, OLSSON, ELEONOR., Martin Sjöström, Pär-Ola Bendahl, Emma Niméus, Lao Saal, Åke Borg & Sofia Gruvberger, 2015 Aug 1, In : Cancer Research. 75, 15, Abstract 4805.

    Research output: Contribution to journalPublished meeting abstract

  5. 2014
  6. 2012
  7. Co-targeting of the PI3K pathway improves the response of BRCA1 deficient breast cancer cells to PARP1 inhibition.

    Siker Kimbung, Biskup, E., Johansson, I., Kristina Aaltonen, Ottosson-Wadlund, A., Sofia Gruvberger, Cunliffe, H., Fadeel, B., Niklas Loman, Berglund, P. & Ingrid Hedenfalk, 2012, In : Cancer Letters. 319, 2, p. 232-241

    Research output: Contribution to journalArticle

  8. Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes.

    Karolina Holm, Grabau, D., Lövgren, K., Aradottir, S., Sofia Gruvberger, Jillian Howlin, Lao Saal, Ethier, S. P., Pär-Ola Bendahl, Stål, O., Per Malmström, Mårten Fernö, Lisa Rydén, Cecilia Hegardt, Åke Borg & Markus Ringnér, 2012, In : Molecular Oncology. 6, 5, p. 494-506

    Research output: Contribution to journalArticle

  9. The retinoblastoma gene undergoes rearrangements in BRCA1-deficient basal-like breast cancer.

    Jönsson, G. B., Staaf, J., Vallon-Christersson, J., Ringnér, M., Gruvberger, S., Saal, L., Holm, K., Hegardt, C., Arason, A., Fagerholm, R., Olsson, C., Grabau, D., Johnsson, E., Lövgren, K., Magnusson, L., Heikkilä, P., Agnarsson, B. A., Johannsson, O. T., Malmström, P., Fernö, M. & 5 othersHåkan Olsson, Niklas Loman, Nevanlinna, H., Barkardottir, R. B. & Åke Borg, 2012, In : Cancer Research. 72, 16, p. 4028-4036

    Research output: Contribution to journalArticle

  10. 2011
  11. 2009
  12. 3-Phosphoinositide-dependent kinase 1 potentiates upstream lesions on the phosphatidylinositol 3-kinase pathway in breast carcinoma

    Maurer, M., Su, T., Saal, L. H., Koujak, S., Hopkins, B. D., Barkley, C. R., Wu, J., Nandula, S., Dutta, B., Xie, Y., Chin, Y. R., Kim, D-I., Ferris, J. S., Gruvberger-Saal, S. K., Laakso, M., Wang, X., Memeo, L., Rojtman, A., Matos, T., Yu, J. S. & 9 othersCordon-Cardo, C., Isola, J., Terry, M. B., Toker, A., Mills, G. B., Zhao, J. J., Murty, V. V. V. S., Hibshoosh, H. & Parsons, R., 2009 Aug 1, In : Cancer Research. 69, 15, p. 6299-306 8 p.

    Research output: Contribution to journalArticle

  13. 2008
  14. Exploring the two-gene ratio in breast cancer-independent roles for HOXB13 and IL17BR in prediction of clinical outcome

    Jerevall, P-L., Brommesson, S., Carina Forsare, Sofia Gruvberger, Per Malmström, Nordenskjöld, B., Wingren, S., Söderkvist, P., Mårten Fernö & Stål, O., 2008, In : Breast Cancer Research and Treatment. 107, 2, p. 225-234

    Research output: Contribution to journalArticle

  15. Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair

    Lao Saal, Sofia Gruvberger, Persson, C., Lövgren, K., Johan Staaf, Göran B Jönsson, Pires, MM., Karolina Holm, Johan Vallon-Christersson, Håkan Olsson, Krogh, M., Isola, J. & Åke Borg, 2008, In : Nature Genetics. 40, 1, p. 102-107

    Research output: Contribution to journalArticle

  16. 2007
  17. Basal-like phenotype is not associated with patient survival in estrogen-receptor-negative breast cancers

    Jumppanen, M., Sofia Gruvberger, Kauraniemi, P., Tanner, M., Pär-Ola Bendahl, Lundin, M., Krogh, M., Kataja, P., Åke Borg, Mårten Fernö & Isola, J., 2007, In : Breast Cancer Research. 9, 1

    Research output: Contribution to journalArticle

  18. Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity

    Lao Saal, Johansson, P., Karolina Holm, Sofia Gruvberger, She, Q-B., Maurer, M., Koujak, S., Ferrando, A. A., Per Malmström, Memeo, L., Isola, J., Pär-Ola Bendahl, Rosen, N., Hibshoosh, H., Markus Ringnér, Åke Borg & Parsons, R., 2007, In : Proceedings of the National Academy of Sciences. 104, 18, p. 7564-7569

    Research output: Contribution to journalArticle

  19. 2006
  20. Is the small heat shock protein alphaB-crystallin an oncogene?

    Sofia Gruvberger & Parsons, R., 2006, In : Journal of Clinical Investigation. 116, 1, p. 30-32

    Research output: Contribution to journalArticle

  21. Microarrays in breast cancer research and clinical practice - the future lies ahead

    Sofia Gruvberger, Cunliffe, H. E., Carr, K. M. & Ingrid Hedenfalk, 2006, In : Endocrine-Related Cancer. 13, 4, p. 1017-1031

    Research output: Contribution to journalReview article

  22. 2005
  23. Estrogen receptor alpha and beta in breast cancer - gene expression profiles and clinical implications

    Sofia Gruvberger, 2005, Department of Oncology, Clinical Sciences, Lund University. 96 p.

    Research output: ThesisDoctoral Thesis (compilation)

  24. 2004
  25. 2003
  26. 2002
  27. Bioarray software environment: a platform for comprehensive management and analysis of microarray data

    Lao Saal, Carl Troein, Johan Vallon-Christersson, Sofia Gruvberger, Åke Borg & Peterson, C., 2002, In : Genome Biology. 3, 8, p. software0003.1-software0003.6 (2002)

    Research output: Contribution to journalArticle

  28. 2001
  29. Gene-expression profiles in hereditary breast cancer

    Hedenfalk, I., Duggan, D., Chen, Y., Radmacher, M., Bittner, M., Simon, R., Meltzer, P., Gusterson, B., Esteller, M., Kallioniemi, O. P., Wilfond, B., Borg, Å., Trent, J., Raffeld, M., Yakhini, Z., Ben-Dor, A., Dougherty, E., Kononen, J., Bubendorf, L., Fehrle, W. & 6 othersPittaluga, S., S Gruvberger, N Loman, Johannsson, O., Håkan Olsson & Sauter, G., 2001 Feb 22, In : New England Journal of Medicine. 344, 8, p. 539-48 10 p.

    Research output: Contribution to journalArticle

  30. Estrogen receptor status in breast cancer is associated with remarkably distinct gene expression patterns

    Sofia Gruvberger, Markus Ringnér, Chen, Y., Panavally, S., Lao Saal, Mårten Fernö, Peterson, C., Meltzer, P. S. & Åke Borg, 2001, In : Cancer Research. 61, 16, p. 5979-5984

    Research output: Contribution to journalArticle