Multiparametric mapping of the brain at 7T using gradient echoes

Project: Research

Research areas and keywords

Keywords

  • MRI, brain, multiparameter mapping

Description

The versatility and high effiecacy of the 3D spoiled gradient-echo sequence is employed for multi-parametric mapping of the brain at 7T. By variable flip angles (VFA) are used to map the transverse relaxation rate R1=1/T1 and proton density, but also magnetisation transfer (MT) if selective MT-pulses are applied off-resonance prior to excitation. Acquiring multiple gradient echoes yields the effective transverse relaxation rate R2*=1/T2*, besides an increase in SNR in VFA experiments. The signal phase is exploited for mapping the local B0 field, which in turn is modeled by quantitative distribution of susceptibility (qSM).
Short titleMPM at 7T
StatusActive
Effective start/end date2016/11/012020/11/01

Collaborative partners

  • Lund University (lead)
  • Danish Research Center for Magnetic Resonance, Hvidovre Hospital
  • Max Planck Institute for Human Cognitive and Brain Sciences

Participants

Related research output

Hampus Olsson, Andersen, M., Jimmy Lätt, Ronnie Wirestam & Gunther Helms, 2019 Apr 29, Magnetization transfer (MT) of human brain at 7T in the context of a 3D multi-parameter mapping protocol. Berkeley: International Society for Magnetic Resonance in Medicine, Vol. 27. 4 p. 309. (Proceedings of the ISMRM; vol. 27).

Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

Balteau, E., Tabelow, K., Ashburner, J., Callaghan, M., Draganski, B., Gunther Helms, Kherif, F., Leutritz, T., Lutti, A., Philips, C., Reimer, E., Ruthotto, L., Seif, M., Weiskopf, N., Ziegler, G. & Mohammadi, S., 2018 Jul 31, Berlin: Weierstraß Institute for Applied Analysis and Stochastics, 35 p.

Research output: Working paper

Gunther Helms, 2015 May 30, Proceedings of the International Society for Magnetic Resonance in Medicine Annual Meeting 2015. Berkeley: International Society for Magnetic Resonance in Medicine, Vol. 23. p. 3360 1 p. 3360. (Proceedings of the ISMRM; vol. 23).

Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

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Related activities

Helms, G. (Role not specified)
2019 Sep 292019 Oct 2

Activity: Talk or presentationPresentation

Helms, G. (Role not specified)
2019 Sep 4

Activity: Consultancy, expert advice and membershipsMember of board/committee/council etc

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