13C imaging-a new diagnostic platform.

Research output: Contribution to journalArticle

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13C imaging-a new diagnostic platform. / Månsson, Sven; Johansson, Edvin; Magnusson, Peter; Chai, Chun-Ming; Hansson, Georg; Petersson, J Stefan; Ståhlberg, Freddy; Golman, Klaes.

In: European Radiology, Vol. 16, No. 1, 2006, p. 57-67.

Research output: Contribution to journalArticle

Harvard

Månsson, S, Johansson, E, Magnusson, P, Chai, C-M, Hansson, G, Petersson, JS, Ståhlberg, F & Golman, K 2006, '13C imaging-a new diagnostic platform.', European Radiology, vol. 16, no. 1, pp. 57-67. https://doi.org/10.1007/s00330-005-2806-x

APA

Månsson, S., Johansson, E., Magnusson, P., Chai, C-M., Hansson, G., Petersson, J. S., ... Golman, K. (2006). 13C imaging-a new diagnostic platform. European Radiology, 16(1), 57-67. https://doi.org/10.1007/s00330-005-2806-x

CBE

Månsson S, Johansson E, Magnusson P, Chai C-M, Hansson G, Petersson JS, Ståhlberg F, Golman K. 2006. 13C imaging-a new diagnostic platform. European Radiology. 16(1):57-67. https://doi.org/10.1007/s00330-005-2806-x

MLA

Vancouver

Månsson S, Johansson E, Magnusson P, Chai C-M, Hansson G, Petersson JS et al. 13C imaging-a new diagnostic platform. European Radiology. 2006;16(1):57-67. https://doi.org/10.1007/s00330-005-2806-x

Author

Månsson, Sven ; Johansson, Edvin ; Magnusson, Peter ; Chai, Chun-Ming ; Hansson, Georg ; Petersson, J Stefan ; Ståhlberg, Freddy ; Golman, Klaes. / 13C imaging-a new diagnostic platform. In: European Radiology. 2006 ; Vol. 16, No. 1. pp. 57-67.

RIS

TY - JOUR

T1 - 13C imaging-a new diagnostic platform.

AU - Månsson, Sven

AU - Johansson, Edvin

AU - Magnusson, Peter

AU - Chai, Chun-Ming

AU - Hansson, Georg

AU - Petersson, J Stefan

AU - Ståhlberg, Freddy

AU - Golman, Klaes

PY - 2006

Y1 - 2006

N2 - he evolution of magnetic resonance imaging (MRI) has been astounding since the early 1980s, and a broad range of applications has emerged. To date, clinical imaging of nuclei other than protons has been precluded for reasons of sensitivity. However, with the recent development of hyperpolarization techniques, the signal from a given number of nuclei can be increased as much as 100,000 times, sufficient to enable imaging of nonproton nuclei. Technically, imaging of hyperpolarized nuclei offers several unique properties, such as complete lack of background signal and possibility for local and permanent destruction of the signal by means of radio frequency (RF) pulses. These properties allow for improved as well as new techniques within several application areas. Diagnostically, the injected compounds can visualize information about flow, perfusion, excretory function, and metabolic status. In this review article, we explain the concept of hyperpolarization and the techniques to hyperpolarize 13C. An overview of results obtained within angiography, perfusion, and catheter tracking is given, together with a discussion of the particular advantages and limitations. Finally, possible future directions of hyperpolarized 13C MRI are pointed out.

AB - he evolution of magnetic resonance imaging (MRI) has been astounding since the early 1980s, and a broad range of applications has emerged. To date, clinical imaging of nuclei other than protons has been precluded for reasons of sensitivity. However, with the recent development of hyperpolarization techniques, the signal from a given number of nuclei can be increased as much as 100,000 times, sufficient to enable imaging of nonproton nuclei. Technically, imaging of hyperpolarized nuclei offers several unique properties, such as complete lack of background signal and possibility for local and permanent destruction of the signal by means of radio frequency (RF) pulses. These properties allow for improved as well as new techniques within several application areas. Diagnostically, the injected compounds can visualize information about flow, perfusion, excretory function, and metabolic status. In this review article, we explain the concept of hyperpolarization and the techniques to hyperpolarize 13C. An overview of results obtained within angiography, perfusion, and catheter tracking is given, together with a discussion of the particular advantages and limitations. Finally, possible future directions of hyperpolarized 13C MRI are pointed out.

KW - Magnetic resonance imaging (MRI)

KW - Hyperpolarized 13C

KW - Metabolic imaging

KW - New imaging applications

U2 - 10.1007/s00330-005-2806-x

DO - 10.1007/s00330-005-2806-x

M3 - Article

VL - 16

SP - 57

EP - 67

JO - European Radiology

JF - European Radiology

SN - 0938-7994

IS - 1

ER -