A comparative study between the two patch-test systems Finn chambers and Finn chambers AQUA

Research output: Contribution to journalArticle

Abstract

Background: Finn Chambers AQUA (FCA) is a development of the Finn Chambers (FC) test system in which the test chambers are mounted on a moisture-resistant adhesive patch. FCA has pre-fixed filter papers. Because the use of FCA does not require any extra taping or use of separate filter papers, a change from FC to FCA chambers may be beneficial for both patients and patch-test technicians. Objectives: To investigate whether there are any differences regarding detection of contact allergy when simultaneous patch testing is performed with FC and FCA. Materials and Methods: Results from 434 dermatitis patients simultaneously tested with 10 allergens in both FC and FCA were evaluated. Results: There were no significant differences regarding detection of positive reactions between the two test systems. There were significantly more doubtful reactions to methylisothiazolinone, fragrance mix I and hydroperoxides of linalool when testing with FCA. We only observed significantly more doubtful reactions in FC regarding nickel(II)sulfate. Irritant reactions to formaldehyde were also significantly more common when using FCA. Conclusion: The FC and FCA had good agreement in detection of positive reactions. However, the results including doubtful and irritant reactions justify further research regarding optimization of the dose.

Details

Authors
Organisations
External organisations
  • Skåne University Hospital
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Dermatology and Venereal Diseases

Keywords

  • Finn chambers, Finn chambers AQUA, patch testing, patch-test system
Original languageEnglish
Pages (from-to)290-298
JournalContact Dermatitis
Volume84
Issue number5
Early online date2020 Dec 24
Publication statusPublished - 2021
Publication categoryResearch
Peer-reviewedYes