A long-term follow-up of clinical response and regional cerebral blood flow changes in depressed patients treated with ECT.

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Abstract

Depression is the leading cause of disability worldwide and electroconvulsive therapy (ECT) is the most potent therapy. We investigated the clinical response and regional cerebral blood flow changes in depressed in patients treated with (ECT) in a repeated longitudinal study. Method: Forty-nine patients (21 men and 28 women) with a mean age 61 years underwent ECT. Forty-one patients grading improvement after the initial ECT-series (responder group) were compared with eight, grading no improvement (non-responder group). The patients underwent neuropsychiatric ratings, measure of clinical response (defined as≥50% reduction of pre-treatment depression score) and measure of regional cerebral blood flow (rCBF).

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  • Psychiatry
Original languageEnglish
Pages (from-to)235-243
JournalJournal of Affective Disorders
Volume167
Issue numberJun 12
Publication statusPublished - 2014
Publication categoryResearch
Peer-reviewedYes

Bibliographic note

The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Department of Psychogeriatrics (013304000), Division of Clinical Chemistry and Pharmacology (013250300)