A MRI and polarized gases compatible respirator and gas administrator for the study of the small animal lung: volume measurement and control

Research output: Contribution to journalArticle

Abstract

We have developed over the past years an experimental magnetic resonance imaging (MRI) and polarized gases compatible mechanical respirator for the study of the small experimental animal. The respirator has been successfully used for experiments both in the MRI setting for polarized (3)He, (19)F, and proton imaging as well as for functional measurements of the lungs. The new main pneumatic valve with the two integrated sensors for simultaneous lung pressure and volume measurements and the proportional valve to set the tidal volume of the respiration are described. It is shown how the device measures and controls the tidal volume of the lungs.

Details

Authors
  • Angelos Kyriazis
  • Rigoberto Perez de Alejo
  • Ignacio Rodriguez
  • Lars E Olsson
  • Jesus Ruiz-Cabello
Organisations
External organisations
  • Complutense University of Madrid
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Radiology, Nuclear Medicine and Medical Imaging

Keywords

  • Animals, Biomedical Research, Gases, Lung Compliance, Lung Volume Measurements, Magnetic Resonance Imaging, Mice, Ventilators, Mechanical
Original languageEnglish
Pages (from-to)1745-9
Number of pages5
JournalIEEE Transactions on Biomedical Engineering
Volume57
Issue number7
Publication statusPublished - 2010 Jul
Publication categoryResearch
Peer-reviewedYes