A multi-centre study on quality of life and absenteeism in patients with CRS referred for endoscopic surgery

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Aims: This study summarises the health-related quality of life (HRQOL) scores and absenteeism caused by sinus problems in patients awaiting surgery with the diagnoses recurrent acute rhinosinusitis (RARS), chronic rhinosinusitis with nasal polyps (CRS+NP) or
CRS without nasal polyps (CRS-NP), in a prospective multi-centre study.
Methodology: Two hundred and seven patients with RARS, CRS+NP or CRS-NP were enrolled. EP3OS definitions of CRS and NP were used. The patients completed the 22 Sinonasal Outcome Test (SNOT-22), the short-form 36-item questionnaire (SF-36), the Hospital Anxiety and Depression Scale (HAD) and a total Visual Analogue Scale (VAS)
regarding rhinosinusitis symptoms.
Results: SNOT-22 and VAS scores indicated severe disease. Comparison of the HRQOL scores in the three rhinosinusitis subgroups showed statistical differences in nine of the SNOT-22 items and in the SF-36 subscale of bodily pain. Mean scores of SF-36 were significantly
lower than that of the normal Swedish population. According to the HAD scores, 28% of the patients had probable or possible anxiety or depression disorder. Fifty-seven percent of the patients reported absenteeism from work due to sinus problems.
Conclusions: RARS, CRS+NP and CRS-NP significantly decrease HRQOL. Some statistically significant differences in HRQOL were found between the three rhinosinusitis subgroups. Absenteeism due to chronic sinus conditions is considerable.


Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Otorhinolaryngology


  • Key words: chronic rhinosinusitis, nasal polyps, recurrent acute rhinosinusitis, health-related quality of life, absenteeism
Original languageEnglish
Pages (from-to)420-428
Issue number4
Publication statusPublished - 2011
Publication categoryResearch

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