A new approach to detection of antigen-antibody complexes by microcalorimetric measurements of heat production in blood cells
Research output: Contribution to journal › Article
Using batch microcalorimeters of the thermopile conduction type, heat production was measured in human blood in the presence of defined antigens and their specific antibodies. A large increase in heat production, reflecting increased metabolic activity in the blood cells, was found when antigens and specific antisera at certain antigen-antibody proportions were mixed with the blood. The reproducibility and specificity of the method were found to be very good. The present results indicate that calorimetry may be a useful technique for detection of antigen-antibody complexes.
|Research areas and keywords||
Subject classification (UKÄ) – MANDATORY
|Journal||Journal of Immunological Methods|
|Publication status||Published - 1980|