A novel framework for classification of selection processes in epidemiological research

Research output: Contribution to journalArticle

Abstract

Background: Selection and selection bias are terms that lack consistent definitions and have varying meaning and usage across disciplines. There is also confusion in current definitions between underlying mechanisms that lead to selection and their consequences. Consequences of selection on study validity must be judged on a case-by-case basis depending on research question, study design and analytical decisions. The overall aim of the study was to develop a simple but general framework for classifying various types of selection processes of relevance for epidemiological research. Methods: Several original articles from the epidemiological literature and from related areas of observational research were reviewed in search of examples of selection processes, used terminology and description of the underlying mechanisms. Results: We classified the identified selection processes in three dimensions: i) selection level (selection at the population level vs. study-specific selection), ii) type of mechanism (selection in exposure vs. selection in population composition), iii) timing of the selection (at exposure entry, during exposure/follow-up or post-outcome). Conclusions: Increased understanding of when, how, and why selection occur is an important step towards improved validity of epidemiological research.

Details

Authors
Organisations
External organisations
  • Skåne University Hospital
  • University of Gothenburg
  • Region Halland
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Public Health, Global Health, Social Medicine and Epidemiology

Keywords

  • Bias, Epidemiologic factors, Population characteristics, Public health, Selection bias
Original languageEnglish
Article number155
JournalBMC Medical Research Methodology
Volume20
Issue number1
Publication statusPublished - 2020
Publication categoryResearch
Peer-reviewedYes

Related projects

Jonas Björk, Anton Nilsson, Ulf Strömberg & Carl Bonander

Swedish Council for Working Life and Social Research (Forte)

2017/07/012020/12/31

Project: Other

View all (1)