A Peristaltic Pump Driven Zr-89 Separation Module

Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

Abstract

To facilitate the separation of Zr-89 produced in yttrium foils, an automated separation module was designed and assembled. The module separates more than 85% of produced Zr-89 - activity in 3 g foils in less than 90 min. About 10 % remains in the dissolving vial. The quality of the separated Zr-89 activity was investigated for labeling of the HER2-binding monoclonal antibody fragment, trastuzumab-Fab.

Details

Authors
  • Jonathan Siikanen
  • Mikael Peterson
  • T. A. Tran
  • Per Roos
  • Tomas G Ohlsson
  • Anders Sandell
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Radiology, Nuclear Medicine and Medical Imaging

Keywords

  • Zr-89, PET, Separation Module, Automation
Original languageEnglish
Title of host publication14th International Workshop on Targetry and Target Chemistry
PublisherAmerican Institute of Physics
Pages206-210
Volume1509
Publication statusPublished - 2012
Publication categoryResearch
Peer-reviewedYes
Event14th International Workshop on Targetry and Target Chemistry (WTTC) - Playa del Carmen, Mexico
Duration: 2012 Aug 262012 Aug 29

Publication series

Name
Volume1509
ISSN (Print)1551-7616
ISSN (Electronic)0094-243X

Conference

Conference14th International Workshop on Targetry and Target Chemistry (WTTC)
CountryMexico
CityPlaya del Carmen
Period2012/08/262012/08/29