A personalized approach to the management of VWD

Research output: Contribution to journalArticle

Abstract

The goal of treating Von Willebrand Disease (VWD) is to replace deficient or dysfunctional Von Willebrand Factor (VWF) protein. However, the choice of treatment has to be considered carefully in view of patient factors and the unique properties of replacement products. Tailoring a treatment plan to an individual patient's bleeding challenge is an intricate process. This review describes personalization of treatment selection for desmopressin (DDAVP), VWF replacement concentrates, including the newly available recombinant VWF (rVWF) and prophylaxis as a treatment approach in VWD.

Details

Authors
Organisations
External organisations
  • Skåne University Hospital
  • University of Western Ontario
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Hematology

Keywords

  • Management of von Willebrand Disease, Personalization of von Willebrand Disease, Personalized approach to von Willebrand Disease, Treatment of von Willebrand Disease
Original languageEnglish
JournalTransfusion and Apheresis Science
Publication statusE-pub ahead of print - 2019 Aug 7
Publication categoryResearch
Peer-reviewedYes