A Polar Cannabinoid from Cannabis sativa var. Carma

Research output: Contribution to journalArticle

Abstract

The aerial parts of Cannabis saliva var. Carma afforded a novel polar cannabinoid whose structure was established as rac-6',7'-dihydro,6',7'-dihydroxycannabigerol (carmagerol, 1) on the basis of spectroscopic data and semisynthesis from cannabigerol (2a). The dihydroxylation of the omega-double bond was detrimental to the anti-bacterial activity.

Details

Authors
  • Giovanni Appendino
  • Anna Giana
  • Simon Gibbons
  • Massimo Maffei
  • Giorgio Gnavi
  • Gianpaolo Grassi
  • Olov Sterner
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Organic Chemistry

Keywords

  • cannabigerol, carmagerol, Cannabis sativa, Cannabinaceae, activity, antibacterial
Original languageEnglish
Pages (from-to)1977-1980
JournalNatural Product Communications
Volume3
Issue number12
Publication statusPublished - 2008
Publication categoryResearch
Peer-reviewedYes

Bibliographic note

The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Organic chemistry (S/LTH) (011001240)