A Rigid Disc for Protection of Exposed Blood Vessels During Negative Pressure Wound Therapy

Research output: Contribution to journalArticle


Background. There are increasing reports of serious complications and deaths associated with negative pressure wound therapy (NPWT). Bleeding may occur when NPWT is applied to a wound with exposed blood vessels. Inserting a rigid disc in the wound may protect these structures. The authors examined the effects of rigid discs on wound bed tissue pressure and blood flow through a large blood vessel in the wound bed during NPWT. Methods. Wounds were created over the femoral artery in the groin of 8 pigs. Rigid discs were inserted. Wound bed pressures and arterial blood flow were measured during NPWT. Results. Pressure transduction to the wound bed was similar for control wounds and wounds with discs. Blood flow through the femoral artery decreased in control wounds. When a disc was inserted, the blood flow was restored. Conclusions. NPWT causes hypoperfusion in the wound bed tissue, presumably as a result of mechanical deformation. The insertion of a rigid barrier alleviates this effect and restores blood flow.


Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Surgery


  • experimental surgery, wound healing, negative pressure wound therapy, microvascular blood flow
Original languageEnglish
Pages (from-to)74-80
JournalSurgical Innovation
Issue number1
Publication statusPublished - 2013
Publication categoryResearch

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Research output: ThesisDoctoral Thesis (compilation)

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