Abnormal oral vascular network pattern geometry: A new clinical sign of Down syndrome

Research output: Contribution to journalArticle

Abstract

Down syndrome is a leading genetic cause of mental retardation. Here, we show high fractal dimensions and Lempel-Ziv complexity and lower minimum path fractal dimension (P <= .0006) for the oral vascular networks of patients (n = 14) and their unaffected parents. This newly recognized sign may provide a useful phenotypical marker for identifying couples potentially at risk for offspring with Down syndrome.

Details

Authors
  • G Latini
  • G Bianciardi
  • S Parrini
  • Ricardo Laurini
  • C De Felice
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Obstetrics, Gynecology and Reproductive Medicine
Original languageEnglish
Pages (from-to)132-137
JournalJournal of Pediatrics
Volume148
Issue number1
Publication statusPublished - 2006
Publication categoryResearch
Peer-reviewedYes