ABO blood group does not impact incidence or outcomes of surgery for acute type A aortic dissection

Research output: Contribution to journalArticle

Abstract

Objectives. To evaluate the distribution and impact of ABO blood groups on postoperative outcomes in patients undergoing surgery for acute type A aortic dissection (ATAAD). Design. A total of 1144 surgical ATAAD patients from eight Nordic centres constituting the Nordic consortium for acute type A aortic dissection (NORCAAD) were analysed. Blood group O patients were compared to non-O subjects. The relative frequency of blood groups was assessed with t-distribution, modified for weighted proportions. Multivariable logistic regression was performed to identify independent predictors of 30-day mortality. Cox regression analyses were performed for assessing independent predictors of late mortality. Results. There was no significant difference in the proportions of blood group O between the study populations in the NORCAAD registry and the background population (40.6 (95% CI 37.7–43.4)% vs 39.0 (95% CI 39.0–39.0)%). ABO blood group was not associated with any significant change in risk of 30-day or late mortality, with the exception of blood group A being an independent predictor of late mortality. Prevalence of postoperative complications was similar between the ABO blood groups. Conclusions. In this large cohort of Nordic ATAAD patients, there were no associations between ABO blood group and surgical incidence or outcomes, including postoperative complications and survival.

Details

Authors
Organisations
External organisations
  • Skåne University Hospital
  • Aarhus University Hospital Skejby
  • Karolinska University Hospital
  • University of Gothenburg
  • Tampere University Hospital
  • Turku University Hospital
  • Yale University
  • Örebro University Hospital
  • National University Hospital of Iceland
  • University of Turku
  • Örebro University
  • University of Iceland
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Cardiac and Cardiovascular Systems
  • Hematology

Keywords

  • aneurysm, Aorta, blood group, dissection, NORCAAD
Original languageEnglish
JournalScandinavian Cardiovascular Journal
Publication statusE-pub ahead of print - 2019 Oct 23
Publication categoryResearch
Peer-reviewedYes