Additional transplantation of ex vivo generated megakaryocytic cells after high-dose chemotherapy

Research output: Contribution to journalLetter


The additional transplantation of ex vivo generated hematopoietic (post)-progenitor cells represents a possible approach to ameliorate high-dose chemotherapy induced cytopenia. We investigated the feasibility of the large-scale expansion and transplantation of autologous megakaryocytic cells in four patients with advanced solid tumors. Up to 1,460x10(6) ex vivo generated cells were administered without adverse effects but no clear cut effect on platelet recovery was observed.


  • Stefan Scheding
  • Markus Bergmannn
  • Gisa Rathke
  • Wichard Vogel
  • Wolfram Brugger
  • Lothar Kanz
External organisations
  • External Organization - Unknown
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Hematology
Original languageEnglish
Pages (from-to)630-631
Issue number5
Publication statusPublished - 2004
Publication categoryResearch
Externally publishedYes

Bibliographic note

The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Hematology/Transplantation (013022014)