Akut leversvikt ­- viktigt med snabb multidisciplinär handläggning

Research output: Contribution to journalArticle

Abstract

A recent study in Sweden on patients with acute liver failure (ALF) 1994-2003 demonstrated that the most common causes were paracetamol toxicity (42%) and idiosyncratic drug reactions (15%). In 11% of cases of ALF no definite etiology could be established. Among patients with paracetamol toxicity, the spontaneous survival without liver transplantation was 82% compared to 49% in patients with reactions to other drugs and 29% among the patients with indeterminate cause. Patients with ALF need a rapid and effective diagnostic work-up to detect the etiology as this often determines the outcome. In ALF it is of major importance to make an early contact with a transplant centre as the search for a suitable donor organ may take time in patients who are candidates for a liver transplantation. Patients with acute liver failure need a multidisciplinary care with co-operation between hepatologists, intensive care unit specialists and transplant surgeons.

Details

Authors
  • Einar Bjornsson
  • Gu Wei
  • Annika Bergquist
  • Ulrika Broome
  • Sven Wallerstedt
  • Sven Almer
  • Per Sangfelt
  • Ake Danielsson
  • Hanna Sandberg-Gertzen
  • Lars Loof
  • Hanne Prytz
  • Stefan Lindgren
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Rheumatology and Autoimmunity
  • Other Clinical Medicine

Keywords

  • Akut leversvikt
Translated title of the contributionAcute liver failure--rapid multidisciplinary management
Original languageSwedish
Pages (from-to)210-213
JournalLäkartidningen
Volume104
Issue number4
Publication statusPublished - 2007
Publication categoryResearch
Peer-reviewedYes