Allogeneic Hematopoietic Stem Cell Transplantation in the Treatment of Human C1q Deficiency: The Karolinska Experience.

Research output: Contribution to journalArticle

Abstract

Human C1q deficiency is associated with systemic lupus erythematosus (SLE) and increased susceptibility to severe bacterial infections. These patients require extensive medical therapy and some develop treatment-resistant disease. Because C1q is produced by monocytes, it has been speculated that allogeneic hematopoietic stem cell transplantation (allo-HSCT) may cure this disorder.

Details

Authors
  • Richard F Olsson
  • Stefan Hagelberg
  • Bodil Schiller
  • Olle Ringdén
  • Lennart Truedsson
  • Anders Åhlin
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Rheumatology and Autoimmunity
Original languageEnglish
JournalTransplantation
Early online date2015 Oct 29
Publication statusPublished - 2015
Publication categoryResearch
Peer-reviewedYes