An auxin-driven polarized transport model for phyllotaxis

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An auxin-driven polarized transport model for phyllotaxis. / Jönsson, Henrik; Heisler, M; Shapiro, BE; Meyerowitz, EM; Mjolsness, E.

In: Proceedings of the National Academy of Sciences, Vol. 103, No. 5, 2006, p. 1633-1638.

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Jönsson, Henrik ; Heisler, M ; Shapiro, BE ; Meyerowitz, EM ; Mjolsness, E. / An auxin-driven polarized transport model for phyllotaxis. In: Proceedings of the National Academy of Sciences. 2006 ; Vol. 103, No. 5. pp. 1633-1638.

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TY - JOUR

T1 - An auxin-driven polarized transport model for phyllotaxis

AU - Jönsson, Henrik

AU - Heisler, M

AU - Shapiro, BE

AU - Meyerowitz, EM

AU - Mjolsness, E

PY - 2006

Y1 - 2006

N2 - Recent studies show that plant organ positioning may be mediated by localized concentrations of the plant hormone auxin. Auxin patterning in the shoot apical meristem is in turn brought about by the subcellular polar distribution of the putative auxin efflux mediator, PIN1. However, the question of what signals determine PIN1 polarization and how this gives rise to regular patterns of auxin concentration remains unknown. Here we address these questions by using mathematical modeling combined with confocal imaging. We propose a model that is based on the assumption that auxin influences the polarization of its own efflux within the meristem epidermis. We show that such a model is sufficient to create regular spatial patterns of auxin concentration on systems with static and dynamic cellular connectivities, the latter governed by a mechanical model. We also optimize parameter values for the PIN1 dynamics by using a detailed auxin transport model, for which parameter values are taken from experimental estimates, together with a template consisting of cell and wall compartments as well as PIN1 concentrations quantitatively extracted from confocal data. The model shows how polarized transport can drive the formation of regular patterns.

AB - Recent studies show that plant organ positioning may be mediated by localized concentrations of the plant hormone auxin. Auxin patterning in the shoot apical meristem is in turn brought about by the subcellular polar distribution of the putative auxin efflux mediator, PIN1. However, the question of what signals determine PIN1 polarization and how this gives rise to regular patterns of auxin concentration remains unknown. Here we address these questions by using mathematical modeling combined with confocal imaging. We propose a model that is based on the assumption that auxin influences the polarization of its own efflux within the meristem epidermis. We show that such a model is sufficient to create regular spatial patterns of auxin concentration on systems with static and dynamic cellular connectivities, the latter governed by a mechanical model. We also optimize parameter values for the PIN1 dynamics by using a detailed auxin transport model, for which parameter values are taken from experimental estimates, together with a template consisting of cell and wall compartments as well as PIN1 concentrations quantitatively extracted from confocal data. The model shows how polarized transport can drive the formation of regular patterns.

KW - meristern

KW - formation

KW - pattern

KW - dynamical model

KW - Arabidopsis thaliana

KW - computable plant

U2 - 10.1073/pnas.0509839103

DO - 10.1073/pnas.0509839103

M3 - Article

VL - 103

SP - 1633

EP - 1638

JO - Proceedings of the National Academy of Sciences

T2 - Proceedings of the National Academy of Sciences

JF - Proceedings of the National Academy of Sciences

SN - 1091-6490

IS - 5

ER -