An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state.

Research output: Contribution to journalArticle

Abstract

Key points Hematopoietic stem cell aging associate with stable transcriptional alterations that persist through transplantation.Somatic cell reprogramming of aged hematopoietic stem and progenitor cells reverses functional defects associated with hematopoietic aging.

Details

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Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Hematology
Original languageEnglish
Pages (from-to)4257-4264
JournalBlood
Volume121
Issue number21
Publication statusPublished - 2013
Publication categoryResearch
Peer-reviewedYes

Bibliographic note

The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Stem Cell Center (013041110), Reproductive Immunology (013212062), Stem Cell Aging (013212073), BMC Biomedical Centre (0130322000), Neuroinflammation (013210006)

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Related research output

Martin Wahlestedt, 2014, Stem Cell Aging. 164 p.

Research output: ThesisDoctoral Thesis (compilation)

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