An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state.

Research output: Contribution to journalArticle

Bibtex

@article{cf2aa42c3c1641e2bbf0dc6b1681e891,
title = "An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state.",
abstract = "Key points Hematopoietic stem cell aging associate with stable transcriptional alterations that persist through transplantation.Somatic cell reprogramming of aged hematopoietic stem and progenitor cells reverses functional defects associated with hematopoietic aging.",
author = "Martin Wahlestedt and Gudmundur Norddahl and Gerd Sten and Amol Ugale and {Micha Frisk}, Mary-Ann and Ragnar Mattsson and Tomas Deierborg and Mikael Sigvardsson and David Bryder",
note = "The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Stem Cell Center (013041110), Reproductive Immunology (013212062), Stem Cell Aging (013212073), BMC Biomedical Centre (0130322000), Neuroinflammation (013210006)",
year = "2013",
doi = "10.1182/blood-2012-11-469080",
language = "English",
volume = "121",
pages = "4257--4264",
journal = "Blood",
issn = "1528-0020",
publisher = "American Society of Hematology",
number = "21",

}