Antioxidant galloylated flavonoids from Geranium tuberosum L. subsp tuberosum

Research output: Contribution to journalArticle

Abstract

Phytochemical investigations on the most active EtOAc extract led to the isolation of 9 flavonoids [quercetin (1), quercetin 3-O-beta-glucopyranoside (2), quercetin 3-O-beta-galactopyranoside (3), quercetin 3-O-(2 ''-O-galloyl)-beta-glucopyranoside (4), quercetin 3-O-(2 ''-O-galloyl)-beta-galactopyranoside (5), quercetin 3-O-(6 ''-O-galloyl)-beta-glucopyranoside (6), quercetin 3-O-(6 ''-O-galloyl)-beta-galactopyranoside (7), quercetin-3-O-alpha-arabinofuranoside (8), and quercetin-3-O-alpha-rhamnopyranosyl-(1 -> 6)-beta-glucopyranoside (9)] and a simple phenolic compound (methyl gallate) (10). The structures of the compounds were elucidated by 1- and 2-dimensional NMR techniques (H-1, C-13, COSY, HMBC, and HMQC) and ESI-TOF-MS spectrometry. H2O2-induced lipid peroxidation inhibitor effects in human red blood cells of different extracts of G. tuberosum L. subsp. tuberosum aerial parts were also investigated. All the compounds tested showed antioxidant activity.

Details

Authors
  • Didem Sohretoglu
  • Mahmut Koray Sakar
  • Suna Atasayar Sabuncuoglu
  • Hilal Oezguenes
  • Olov Sterner
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Organic Chemistry

Keywords

  • antioxidant, gallate, methyl, flavonoids, G. tuberosum L. subsp tuberosum, flavonol gallate
Original languageEnglish
Pages (from-to)685-692
JournalTurkish Journal of Chemistry
Volume33
Issue number5
Publication statusPublished - 2009
Publication categoryResearch
Peer-reviewedYes

Bibliographic note

The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Organic chemistry (S/LTH) (011001240)