Antiproliferative effects of peracetylated naphthoxylosides.

Research output: Contribution to journalArticle

Abstract

The antiproliferative activity, and the capability of priming of glycosaminoglycan chains, of two series of peracetylated mono- and bis-xylosylated dihydroxynaphthalenes have been investigated for normal HFL-1 cells, as well as transformed T24 cells, and compared to the unprotected analogs. Our data show increased antiproliferative activity upon peracetylation, but a loss of selectivity towards T24 cells.

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Subject classification (UKÄ) – MANDATORY

  • Medicinal Chemistry
Original languageEnglish
Pages (from-to)1763-1766
JournalBioorganic & Medicinal Chemistry Letters
Volume19
Publication statusPublished - 2009
Publication categoryResearch
Peer-reviewedYes

Related research output

Aili, U., 2013, Glycobiology, Dept of Experimental Medical Science. 94 p.

Research output: ThesisDoctoral Thesis (compilation)

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