Apicidin Sensitizes Pancreatic Cancer Cells to Gemcitabine by Epigenetically Regulating MUC4 Expression.

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Abstract

Mucin 4 (MUC4) has been linked to resistance to gemcitabine in pancreatic cancer cells. The aim of the present study was to assess whether epigenetic control of MUC4 expression can sensitize pancreatic cancer cells to gemcitabine treatment.

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Subject classification (UKÄ) – MANDATORY

  • Cancer and Oncology
Original languageEnglish
Pages (from-to)5269-5276
JournalAnticancer research
Volume34
Issue number10
Publication statusPublished - 2014
Publication categoryResearch
Peer-reviewedYes