Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data.

Research output: Contribution to journalArticle

Abstract

To use the rs1229984 variant in the alcohol dehydrogenase 1B gene (ADH1B) as an instrument to investigate the causal role of alcohol in cardiovascular disease.

Details

Authors
  • Michael V Holmes
  • Caroline E Dale
  • Luisa Zuccolo
  • Richard J Silverwood
  • Yiran Guo
  • Zheng Ye
  • David Prieto-Merino
  • Abbas Dehghan
  • Stella Trompet
  • Andrew Wong
  • Alana Cavadino
  • Dagmar Drogan
  • Sandosh Padmanabhan
  • Shanshan Li
  • Ajay Yesupriya
  • Maarten Leusink
  • Johan Sundstrom
  • Jaroslav A Hubacek
  • Hynek Pikhart
  • Daniel I Swerdlow
  • Andrie G Panayiotou
  • Svetlana A Borinskaya
  • Chris Finan
  • Sonia Shah
  • Karoline B Kuchenbaecker
  • Tina Shah
  • Jorgen Engmann
  • Lasse Folkersen
  • Per Eriksson
  • Fulvio Ricceri
  • Carlotta Sacerdote
  • Dale M Gamble
  • Sruti Rayaprolu
  • Owen A Ross
  • Stela McLachlan
  • Olga Vikhireva
  • Ivonne Sluijs
  • Robert A Scott
  • Vera Adamkova
  • Leon Flicker
  • Frank M van Bockxmeer
  • Christine Power
  • Pedro Marques-Vidal
  • Tom Meade
  • Michael G Marmot
  • Jose M Ferro
  • Sofia Paulos-Pinheiro
  • Steve E Humphries
  • Philippa J Talmud
  • Irene Mateo Leach
  • Niek Verweij
  • Allan Linneberg
  • Tea Skaaby
  • Pieter A Doevendans
  • Maarten J Cramer
  • Pim van der Harst
  • Olaf H Klungel
  • Nicole F Dowling
  • Anna F Dominiczak
  • Meena Kumari
  • Andrew N Nicolaides
  • Cornelia Weikert
  • Heiner Boeing
  • Shah Ebrahim
  • Tom R Gaunt
  • Jackie F Price
  • Lars Lannfelt
  • Anne Peasey
  • Ruzena Kubinova
  • Andrzej Pajak
  • Sofia Malyutina
  • Mikhail I Voevoda
  • Abdonas Tamosiunas
  • Anke H Maitland-van der Zee
  • Paul E Norman
  • Graeme J Hankey
  • Manuela M Bergmann
  • Albert Hofman
  • Oscar H Franco
  • Jackie Cooper
  • Jutta Palmen
  • Wilko Spiering
  • Pim A de Jong
  • Diana Kuh
  • Rebecca Hardy
  • Andre G Uitterlinden
  • M Arfan Ikram
  • Ian Ford
  • Elina Hyppönen
  • Osvaldo P Almeida
  • Nicholas J Wareham
  • Kay-Tee Khaw
  • Anders Hamsten
  • Lise Lotte N Husemoen
  • Anne Tjønneland
  • Janne S Tolstrup
  • Eric Rimm
  • Joline W J Beulens
  • W M Monique Verschuren
  • N Charlotte Onland-Moret
  • Marten H Hofker
  • S Goya Wannamethee
  • Peter H Whincup
  • Richard Morris
  • Astrid M Vicente
  • Hugh Watkins
  • Martin Farrall
  • J Wouter Jukema
  • James Meschia
  • L Adrienne Cupples
  • Stephen J Sharp
  • Myriam Fornage
  • Charles Kooperberg
  • Andrea Z LaCroix
  • James Y Dai
  • Matthew B Lanktree
  • David S Siscovick
  • Eric Jorgenson
  • Bonnie Spring
  • Josef Coresh
  • Yun R Li
  • Sarah G Buxbaum
  • Pamela J Schreiner
  • R Curtis Ellison
  • Michael Y Tsai
  • Sanjay R Patel
  • Susan Redline
  • Andrew D Johnson
  • Ron C Hoogeveen
  • Hakon Hakonarson
  • Jerome I Rotter
  • Eric Boerwinkle
  • Paul I W de Bakker
  • Mika Kivimaki
  • Folkert W Asselbergs
  • Naveed Sattar
  • Debbie A Lawlor
  • John Whittaker
  • George Davey Smith
  • Kenneth Mukamal
  • Bruce M Psaty
  • James G Wilson
  • Leslie A Lange
  • Ajna Hamidovic
  • Aroon D Hingorani
  • Børge G Nordestgaard
  • Martin Bobak
  • David A Leon
  • Claudia Langenberg
  • Tom M Palmer
  • Alex P Reiner
  • Brendan J Keating
  • Frank Dudbridge
  • Juan P Casas
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Cardiac and Cardiovascular Systems
Original languageEnglish
Pages (from-to)g4164
JournalB M J: British Medical Journal
Volume349
Issue numberJul 10
Publication statusPublished - 2014
Publication categoryResearch
Peer-reviewedYes

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