Association between bleeding tendency and health-related quality of life in carriers of moderate and severe haemophilia.

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Abstract

Carriers of severe and moderate haemophilia A and B are expected to have approximately 50% of the normal level of factors VIII and IX. However, due to X chromosome inactivation in early embryonic life, factor levels can vary considerably. This can lead to increased bleeding tendency, which may in turn impact on health-related quality of life (HRQOL).

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Subject classification (UKÄ) – MANDATORY

  • Hematology
Original languageEnglish
Pages (from-to)742-746
JournalHaemophilia
Volume21
Issue number6
Publication statusPublished - 2015
Publication categoryResearch
Peer-reviewedYes