Association between visual impairment and functional and morphological cerebral abnormalities in full-term children

Research output: Contribution to journalArticle


Purpose: To characterise the nature and degree of ocular disorders and cerebral morphological and functional abnormalities in a population-based group of visually impaired full-term pre-school children. Methods: Forty-five children who were born at full-term between 1989 and 1995 in Varmland, Sweden, were reported as being visually impaired. An ophthalmological examination was performed and clinical data regarding mental development and neurological disease were obtained for all children. Cerebral imaging was performed in 35 children, Results: Twenty-six per cent of the children were found to have ocular disorders only. Forty-two per cent had cerebral morphological abnormalities, verified by cerebral imaging, and 65% had signs of cerebral functional abnormalities. In total, 74% were found to have cerebral morphological and/or cerebral functional abnormalities. Conclusion: The majority of children with visual impairment, including children with ocular disorders, were found to have cerebral morphological and/or cerebral functional abnormalities. We suggest that any child with visual impairment should therefore undergo cerebral imaging and be examined by a paediatrician in order to establish the correct diagnosis.


Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Ophthalmology


  • cerebral lesions, full-term children, ocular disorders, visual impairment
Original languageEnglish
Pages (from-to)140-146
JournalActa Ophthalmologica Scandinavica
Issue number2
Publication statusPublished - 2001
Publication categoryResearch