Associations between homocysteine, bone turnover, BMD, mortality, and fracture risk in elderly women

Research output: Contribution to journalArticle

Abstract

Homocysteine has been suggested to be a risk factor for fracture, but the causal relationship is not clear. In 996 women from the OPRA study, high homocysteine level was associated with high bone marker levels and low BMD at baseline. During a mean 7-year follow-up, high homocysteine level was associated with mortality, but no clear association to fracture risk existed.

Details

Authors
  • Paul Gerdhem
  • Kaisa Ivaska
  • Anders Isaksson
  • Kim Pettersson
  • H. Kalervo Vaananen
  • Karl Obrant
  • Kristina Åkesson
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Orthopedics

Keywords

  • fracture, mortality, ultrasound, bone, BMD, vitamin B-12 folate, homocysteine, aging, population studies, bone metabolic markers
Original languageEnglish
Pages (from-to)127-134
JournalJournal of Bone and Mineral Research
Volume22
Issue number1
Publication statusPublished - 2007
Publication categoryResearch
Peer-reviewedYes