Attenuation of Experimental Atherosclerosis by Interleukin-19.
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Attenuation of Experimental Atherosclerosis by Interleukin-19. / Ellison, Stephen; Gabunia, Khatuna; Kelemen, Sheri E; England, Ross N; Scalia, Rosario; Richards, James M; Orr, Wayne; Traylor, James G; Rogers, Thomas; Cornwell, William; Berglund, Lisa; Goncalves, Isabel; Gomez, Maria; Autieri, Michael V.
In: Arteriosclerosis, Thrombosis and Vascular Biology, Vol. 33, No. 10, 2013, p. 2316-2324.Research output: Contribution to journal › Article
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T1 - Attenuation of Experimental Atherosclerosis by Interleukin-19.
AU - Ellison, Stephen
AU - Gabunia, Khatuna
AU - Kelemen, Sheri E
AU - England, Ross N
AU - Scalia, Rosario
AU - Richards, James M
AU - Orr, Wayne
AU - Traylor, James G
AU - Rogers, Thomas
AU - Cornwell, William
AU - Berglund, Lisa
AU - Goncalves, Isabel
AU - Gomez, Maria
AU - Autieri, Michael V
PY - 2013
Y1 - 2013
N2 - Interleukin-19 (IL-19) is a putative Th2, anti-inflammatory interleukin. Its expression and potential role in atherogenesis are unknown. IL-19 is not detected in normal artery and is expressed to a greater degree in plaque from symptomatic versus asymptomatic patients, suggesting a compensatory counter-regulatory function. We tested whether IL-19 could reduce atherosclerosis in susceptible mice and identified plausible mechanisms.
AB - Interleukin-19 (IL-19) is a putative Th2, anti-inflammatory interleukin. Its expression and potential role in atherogenesis are unknown. IL-19 is not detected in normal artery and is expressed to a greater degree in plaque from symptomatic versus asymptomatic patients, suggesting a compensatory counter-regulatory function. We tested whether IL-19 could reduce atherosclerosis in susceptible mice and identified plausible mechanisms.
U2 - 10.1161/ATVBAHA.113.301521
DO - 10.1161/ATVBAHA.113.301521
M3 - Article
C2 - 23950143
VL - 33
SP - 2316
EP - 2324
JO - Arteriosclerosis, Thrombosis and Vascular Biology
JF - Arteriosclerosis, Thrombosis and Vascular Biology
SN - 1524-4636
IS - 10
ER -