Baseline heterogeneity in glucose metabolism marks the risk for type 1 diabetes and complicates secondary prevention.

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Abstract

Non-diabetic children with multiple islet autoantibodies were recruited to a secondary prevention trial. The objective was to determine the predictive value of baseline (1) HbA1c and metabolic variables derived from intravenous (IvGTT) and oral glucose tolerance tests (OGTT), (2) insulin resistance and (3) number, type and levels of islet autoantibodies, for progression to type 1 diabetes.

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  • Endocrinology and Diabetes
Original languageEnglish
Pages (from-to)473-481
JournalActa Diabetologica
Volume52
Issue number3
Publication statusPublished - 2015
Publication categoryResearch
Peer-reviewedYes

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