Biocompatible lecithin organogels: Structure and phase equilibria

Research output: Contribution to journalArticle

Abstract

The microstructure of organogels formed upon the addition of tiny amounts of water to a solution of lecithin in fatty acid esters (viz. isopropylpalmitate and ethyloleate) was investigated by means of molecular self-diffusion measurements. In both systems lecithin and water form disconnected cylindrical reverse micelles. The ternary phase map for the lecithin/water/isopropylpalmitate has been investigated in detail. The organogel exists in a narrow region close to the lecithin-oil binary axis; for higher water content equilibrium between lamellae and reverse micelles is found. Lamellar phase occupies the lecithin-rich region, close to the lecithin corner (with the exception of a small island of hexagonal phase) and coexists with neat water close to the water-lecithin axis. The remaining part of the phase map shows the three-phase coexistence of water, oil, and lamellar phase.

Details

Authors
  • R Angelico
  • A Ceglie
  • G Colafemmina
  • F Lopez
  • S Murgia
  • Ulf Olsson
  • G Palazzo
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Physical Chemistry
Original languageEnglish
Pages (from-to)140-148
JournalLangmuir
Volume21
Issue number1
Publication statusPublished - 2005
Publication categoryResearch
Peer-reviewedYes