Biologically active metabolites from the basidiomycete Limacella illinita (Fr.) Murr.

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Abstract

In the course of our search for new bioactive compounds from basidiomycetes, four new compounds were isolated from fermentations of Limacella illinita. Illinitone A (1) exhibited weak phytotoxic and moderate nematicidal activities against Caenorhabditis elegans, illinitone B (2) was moderately cytotoxic, while limacellone (3) exhibited weak cytotoxic and phytotoxic activities. The muurolane sesquiterpene 4a was found to be inactive in the assays performed here. Limacellone (3), which appeared to be related with the illinitones 1 and 2, has a new C-15 carbon skeleton. It is possible that compounds 1, 2 and 3 are terpenoids/secoterpenoids, but their biosyntheses were not investigated.

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Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Organic Chemistry

Keywords

  • limacellone, Limacella illinita, illinitones, 11-desoxyeleganthol
Original languageEnglish
Pages (from-to)808-812
JournalZeitschrift fuer Naturforschung. Section C: A Journal of Biosciences
Volume62
Issue number11-12
Publication statusPublished - 2007
Publication categoryResearch
Peer-reviewedYes

Bibliographic note

The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Organic chemistry (S/LTH) (011001240)