Biosensing using arrays of vertical semiconductor nanowires: mechanosensing and biomarker detection

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Abstract

Due to their high aspect ratio and increased surface-to-foot-print area, arrays of vertical semiconductor nanowires are used in numerous biological applications, such as cell transfection and biosensing. Here we focus on two specific valuable biosensing approaches that, so far, have received relatively limited attention in terms of their potential capabilities: cellular mechanosensing and lightguiding-induced enhanced fluorescence detection. Although proposed a decade ago, these two applications for using vertical nanowire arrays have only very recently achieved significant breakthroughs, both in terms of understanding their fundamental phenomena, and in the ease of their implementation. We review the status of the field in these areas and describe significant findings and potential future directions.

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  • Nano Technology
Original languageEnglish
Article number214003
JournalNanotechnology
Volume30
Issue number21
Publication statusPublished - 2019 Mar 13
Publication categoryResearch
Peer-reviewedYes