Body composition in patients with Alzheimer's disease and healthy controls

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Abstract

In Alzheimer's disease (AD), decreased physical activity and nutritional problems are parts of the natural course with probable implications on body composition. Body fat and lean body mass were measured with a bioelectrical impedance method in 25 women who had AD according to the criteria of NINCDS- ADRDA and in 63 health age-matched controls. The patients with AD had 9.5 kg lower body weight (p<0.01), due to almost 4.0 kg lower body fat and 6.0 kg lower lean body mass (p<0.001). This might imply a higher risk for morbidity and mortality. Body weight and lean body mass decreased with age in AD patients but not in the healthy control women. In the control group, the unmarried women had more than 13 kg lower body weight and 9 kg lower body fat than the mean values of all other marital status groups (p<0.01). The maintenance of lean body mass in the very healthy old indicate the possibilities for physical activity.

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Subject classification (UKÄ) – MANDATORY

  • Geriatrics
  • Health Sciences
Original languageEnglish
Pages (from-to)17-31
Number of pages15
JournalJournal of Clinical and Experimental Gerontology
Volume14
Issue number1
Publication statusPublished - 1992 Jan 1
Publication categoryResearch
Peer-reviewedYes