Boronic Acid Modified Polymer Nanoparticles for Enhanced Bacterial Deactivation

Research output: Contribution to journalArticle

Abstract

A new method has been developed to enhance the antibacterial efficiency of traditional antibiotics. Chloramphenicol‐imprinted polymer particles were decorated with boronic acid to improve their binding to both Gram‐negative and ‐positive bacteria. The polymer particles have a high antibiotic loading and provide a slow release of the antibiotic payload to deactivate the target bacteria. The boronic acid modified polymer particles not only contribute to enhanced antibacterial efficiency, but also have the potential to act as scavengers to remove unused antibiotic from the environment.

Details

Authors
Organisations
External organisations
  • Lund University
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Biochemistry and Molecular Biology

Keywords

  • antibiotics, drug delivery, molecular imprinting, polymers, template synthesis
Original languageEnglish
Pages (from-to)2991-2995
Number of pages5
JournalChemBioChem
Volume20
Issue number24
Publication statusPublished - 2019
Publication categoryResearch
Peer-reviewedYes