Breastfeeding does not influence the development of inhibitors in haemophilia.

Research output: Contribution to journalArticle

Abstract

Our aim was to test the hypothesis that breastfeeding may reduce development of inhibitors in male infants with haemophilia by inducing an oral immune tolerance to factor VIII. To achieve that goal, we performed a structured epidemiological survey comprising all males born with severe haemophilia A (in all 100 patients, 19 with inhibitors) or haemophilia B (in all 16 patients, six with inhibitors) in Sweden in 1980-99. Our results show no protective effect of breastfeeding.

Details

Authors
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Hematology

Keywords

  • Immune Tolerance, Hemophilia A: immunology, Hemophilia B: immunology, Human, Preschool, Factor VIII: metabolism, Infant, Newborn, Male, Sweden, Autoantibodies: blood, Blood Coagulation Factor Inhibitors: metabolism, Breast Feeding, Child
Original languageEnglish
Pages (from-to)657-659
JournalHaemophilia
Volume8
Issue number5
Publication statusPublished - 2002
Publication categoryResearch
Peer-reviewedYes

Bibliographic note

The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Paediatric Hematologic Research Group (013243020), Emergency medicine/Medicine/Surgery (013240200)

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